Sentences with phrase «human lung development»

Not exact matches

Lung development in humans happens over five different stages.

The study drew data from the Pregnancy Outcomes and Community Health (POUCH) and POUCHmoms studies, which were funded by the National Institute of Child Health and Human Development and the National Heart, Lung, and Blood Institute.

Scientists at the Johns Hopkins Kimmel Cancer Center say they have preliminary evidence in laboratory - grown, human airway cells that a condensed form of cigarette smoke triggers so - called «epigenetic» changes in the cells consistent with the earliest steps toward lung cancer development.

Funding for this study was provided by the Eunice Kennedy Shriver National Institute of Child Health and Human Development; the National Heart, Lung, and Blood Institute; the American Thoracic Society / American Lung Association Partner Grant; and the Respiratory Health Association.

«Our results, and methods, could have implications for the analysis of endogenous and exogeneous compounds in the exhaled breath as biomarkers of systemic and lung diseases, as well as in development of new approaches to study human exposure to airborne contamination.»

Lambs at a gestational age equivalent to that of a 23 - or 24 - week - old human fetus had normal lung and brain development after a month in the artificial womb, the researchers discovered.

B - raf gene mutations have known roles in the development of many human cancers including melanoma, lung and thyroid cancer.

«This association is important for lung development in mouse embryos, and at least for one of these long non-coding RNAs, important for human lung function.»

This factor is the first lung molecular marker during mouse and human development and is essential for lungs to mature properly in an embryo.

«Taken together, these two studies suggest that the new scalable vaccine formulation is likely to prove as effective as the original formulation — which would make it the first protective TB vaccine in humans since BCG, which was introduced almost a century ago,» said Professor Ajit Lalvani, Director of the Tuberculosis Research Centre, National Heart and Lung Institute, Imperial College London and a member of the DAR - 901 development team.

This work was supported in part by grants from the US National Institute of Neurological Disorders and Stroke (R01NS058529), the National Human Genome Research Institute (U54HG003273), a joint NHGRI / National Heart Blood and Lung Institute grant (U54HG006542) to the Baylor Hopkins Center for Mendelian Genomics, and the BCM Intellectual and Developmental Disabilities Research Center, IDDRC Grant Number 5P30HD024064 - 23, from the Eunice Kennedy Shriver National Institute of Child Health and Human Development.

«The development of this microfluidic lung model, as well as other organs - on - chip, holds the promise of improving the physiological relevance of cellular models for more accurate prediction of the effects of toxicants and drugs on humans, and for reducing the use of animals in medical and pharmaceutical research,» said Sonia Grego, Ph.D., research scientist at RTI and the project's principal investigator.

The 19 NIH institutes, centers and offices contributing to the Knockout Mouse Project are: the NIH Office of Strategic Coordination / Common Fund; NCRR; the National Eye Institute; NHGRI; the National Institute of Allergy and Infectious Diseases; the National Heart, Lung and Blood Institute; the National Institute on Aging; the National Institute of Alcohol Abuse and Alcoholism; the National Institute of Arthritis and Musculoskeletal and Skin Diseases; the Eunice Kennedy Shriver National Institute of Child Health and Human Development; NIDCD; the National Institute of Dental and Craniofacial Research; the National Institute of Environmental Health Sciences; the National Institute of General Medical Sciences; the National Institute of Mental Health; the National Institute of Neurological Disorders and Stroke; the National Institute of Diabetes and Digestive and Kidney Diseases; the National Cancer Institute; and the Office of AIDS Research.

The 19 NIH institutes, centers and offices contributing to the contracts are: National Center for Complementary and Alternative Medicine, National Center for Research Resources, National Eye Institute, National Human Genome Research Institute, National Heart, Lung and Blood Institute, National Institute on Aging, National Institute of Alcohol Abuse and Alcoholism, National Institute of Allergy and Infectious Diseases, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute of Child Health and Human Development, National Institute on Deafness and Other Communication Disorders, National Institute of Dental and Craniofacial Research, National Institute on Drug Abuse, National Institute of Environmental Health Sciences, National Institute of General Medical Sciences, National Institute of Mental Health, National Institute of Neurological Disorders and Stroke, National Institute of Nursing Research, and the Office of AIDS Research.

Funding was provided by the Roddenberry Foundation, National Institutes of Health, National Heart, Lung, and Blood Institute, National Eye Institute, National Institute of Child Health and Human Development, National Institute of Mental Health, California Institute of Regenerative Medicine, Prostate Cancer Foundation, and the Leona M. & Harry B. Helmsley Charitable Trust.

One new way that scientists study this process of cellular development — and a way in which they hope to grow replacement tissue for medical treatments in the future — is by recreating the essential features of human brains, eyes, lungs, and guts in a petri dish.

Their findings, published last week in the Proceedings of the National Academy of Sciences, may provide clues for understanding how some forms of human lung cancer initiate and may also aid in the development of tools for successful gene therapy of lung diseases such as cystic fibrosis.

Saiyong Zhu, PhD, Shaohua Xu, PhD, Tao Xu, PhD, Yu Zhang, PhD, and Tianhua Ma, PhD also participated in this research at Gladstone, which was supported by the Roddenberry Foundation, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, the National Energy Institute, the National Heart, Lung and Blood Institute, the National Institute of Mental Health / National Institutes of Health, the California Institute for Regenerative Medicine, the United States Department of Defense and the William K. Bowes, Jr..

The Swedish part of the effort, called the Human Developmental Cell Atlas (HDCA) program, includes researchers from Karolinska Institutet, Stockholm University and KTH, focusing on brain, lung, heart and fetal development during the first 12 -LSB-...]

Funding was provided by the National Heart, Lung, and Blood Institute, National Institute of Child Health and Human Development, National Institute of Drug Abuse, National Institute of General Medical Sciences, California Institute for Regenerative Medicine, Howard Hughes Medical Institute, Canadian Institutes of Health Research, Agilent University Relations, Uehara Memorial Foundation Research, and the UCSF - Gladstone Center for AIDS Research.

Funding was provided by the National Institute of Child Health and Human Development, National Heart, Lung, and Blood Institute, National Eye Institute, California Institute of Regenerative Medicine, National Basic Research Program of China, Chinese Academy of Sciences, and Science and Technology Planning Project of Guangdong Province.

Creating human lung epithelial cells in the lab has been a challenge, and lineage - specific reporters, which indicate each cell's specific type, are key to understanding lung epithelial stem cell development.

A combination of limited human data and a wealth of animal studies show that phthalates, as only one of many chemicals in fragrances, can impair reproduction and development, alter liver and kidney function, damage the heart and lungs, and effect blood clotting.

In indigenous Australians and Papua New Guineans, mingling with the Denisovans (the «other Neanderthal,» an ancestral human living primarily in Asia) introduced genes related to «spermatogenesis, fertilization, cold acclimation, circadian rhythm, development of brain, neural tube, face, and olfactory pit, immunity,» as well as «female pregnancy, development of face, lung, heart, skin, nervous system, and male gonad, visual and smell perception, response to heat, pain, hypoxia, and UV, lipid transport, metabolism, blood coagulation, wound healing, aging.»

«The small and somehow disputable risk of lung cancer development in relation to SHS exposure exemplifies the intricacy of establishing human cancer etiology when omnipresent carcinogens are concerned.