Sentences with phrase «human lupus patients»

And a third clue emerged from their studies: One strain of the knockout mice showed sensitivity to sunlight — a characteristic of human lupus patients that produce antibodies against the Ro protein.

Not exact matches

«We also confirmed that human patients with a missing or malfunctioning DNASE1L3 gene had an abundance of circulating DNA and developed antibodies to it, and that such antibodies were also present in most forms of lupus,» says Reizis.

Animal studies have suggested that overactivation of TLR7 plays a role in lupus, and a gene variant that increases expression of the receptor has been associated with increased lupus risk in human patients.

The next step, Datta says, is to find which fragments of the human histones trigger lupus, then test whether injecting high doses in patients will help them.

Of special note today: gut microbiota species expressing orthologs of human Ro60 might be involved in triggering and sustaining chronic autoimmunity in lupus; The portal vein blood microbiome in patients with liver cirrhosis; A randomized clinical study suggests dietary promotion of short chain fatty acid producing gut microbes as an effective treatment for type 2 diabetes; and the sexual dimorphism of root, flower and leaf microbiomes in the wild strawberry plant