A protein that appears to play a key role in the formation of lymphoma and other tumors by inhibiting a tumor - suppressing gene has been identified by a team of veterinary and
human medicine researchers at the University of California, Davis.
Current research includes collaboration with veterinary and
human medicine researchers at the University of Saskatchewan's College of Medicine, at the Saskatoon Cancer Centre and at other oncology centers in North America.
Not exact matches
In a study to be presented Thursday, Jan. 26, in the oral plenary session at 1:15 p.m. PST, at the Society for Maternal - Fetal
Medicine's annual meeting, The Pregnancy Meeting ™,
researchers with Baylor College of
Medicine, Houston, Texas and University of California, San Diego, La Jolla, California, will present their findings on a study titled, Maternal Diet Structures the Breast Milk Microbiome in Association with
Human Milk Oligosaccharides and Gut - Associated Bacteria.
A study by
researchers at the University of Chicago
Medicine shows that when mice that are genetically susceptible to developing inflammatory bowel disease (IBD) were given antibiotics during late pregnancy and the early nursing period, their offspring were more likely to develop an inflammatory condition of the colon that resembles
human IBD.
Using a mouse model that expresses an altered form of the normal
human prion protein,
researchers at University of California, San Diego School of
Medicine have determined why the
human proteins aren't corrupted when exposed to the elk prions.
Yale School of
Medicine researchers have identified the molecular pathways involved in the aging of
human eggs.
Stahelin and co-investigator Smita Soni, a postdoctoral
researcher at the Indiana University School of
Medicine, found that VP40 is able to assemble in vitro (i.e., in a test tube), without any
human cells present and mediate formation of virus - like particles when the
human lipid phosphatidylserine is found in solution with VP40, but not other control lipids.
Human ES cells had just been isolated for the first time, and
researchers were excited about their potential use in regenerative
medicine.
A team of
researchers at the Stanford University School of
Medicine has used a gene - editing tool known as CRISPR to repair the gene that causes sickle cell disease in
human stem cells, which they say is a key step toward developing a gene therapy for the disorder.
The
researchers headed up by Claudia Vigano and Abigail Bouwman of the
human aDNA laboratory at the Institute of Evolutionary
Medicine — the only laboratory of its kind in Switzerland — studied a thalassemia allele called cod39?
A panel of small molecules that inhibit Zika virus infection, including one that stands out as a potent inhibitor of Zika viral entry into relevant
human cell types, was discovered by
researchers from the Perelman School of
Medicine at the University of Pennsylvania.
Jenifer Fenton, assistant professor and
researcher in the Department of Food Science and
Human Nutrition, and Kari Hortos, associate dean in MSU's College of Osteopathic
Medicine at the Macomb University Center, led the 18 - month, cross-sectional study, which followed 126 healthy, white American males ranging from 48 to 65 years of age.
As the cost of sequencing the
human genome has plummeted in recent years, many medical
researchers have touted the potential of personalized
medicine — exotic therapies and synthetic drugs that are tailored to our individual genetic makeup.
Medical
researchers were not laughing: bears, too, are essential to
human medicine.
According to Sierra,
researchers have managed to identify several molecular pathways that, if modified through
medicine, could one day mimic the life - expanding effects of calorie restriction in
humans, without requiring anyone to eat less.
As reported in a paper published online in the New England Journal of
Medicine,
researchers from Penn
Medicine, Regeneron Pharmaceuticals, and a group of international collaborators studied ANGPTL3 in both
humans and mice.
In this case,
researchers from the Icahn School of
Medicine at Mount Sinai in New York City took tops from two flu strains that circulate only in birds, and connected each one to a
human hemagglutinin stalk.
Medical treatment that targets
human proteins rather than ever - mutating viruses may one day help HIV - positive people whose bodies have built a resistance to «cocktails» currently used to keep them healthy, according to a Keck School of
Medicine of USC
researcher.
Ideally, this helps
researchers design drug compounds that perform similar functions but retain attributes needed for successful
medicines, like nontoxicity and the ability to travel through the
human body.
To investigate,
researchers from the Channing Division of Network
Medicine at Brigham and Women's Hospital, led by Amir Bashan, PhD, and Yang - Yu Liu, PhD, analyzed data from large metagenomic datasets (e.g. the
Human Microbiome Project and Student Microbiome Project) to look at the dynamics of the gut, mouth and skin microbiomes of healthy subjects.
Researchers at the University of California, San Diego School of
Medicine have identified the evolutionary origins of
human herpes simplex virus (HSV)-1 and -2, reporting that the former infected hominids before their evolutionary split from chimpanzees 6 million years ago while the latter jumped from ancient chimpanzees to ancestors of modern
humans — Homo erectus — approximately 1.6 million years ago.
«The imaging technique could shed light on the immune dysfunction that underpins a broad range of neuroinflammatory diseases, such as Alzheimer's disease, depression, post-traumatic stress disorder and addiction,» said Christine Sandiego, PhD, lead author of the study and a
researcher from the department of psychiatry at the Yale School of
Medicine in New Haven, Conn. «This is the first
human study that accurately measures this immune response in the brain.
In a study published in PLOS ONE today, a team of
researchers led by the London School of Hygiene & Tropical
Medicine show for the first time that female mosquitoes infected with malaria parasites are significantly more attracted to
human odour than uninfected mosquitoes.
The research was led by TAU postgraduate student Dr. Elena Milanesi under the guidance of Dr. David Gurwitz of the Department of
Human Molecular Genetics and Biochemistry of TAU's Sackler Faculty of
Medicine and Sagol School of Neuroscience and Dr. Noam Shomron of the Department of Cell and Developmental Biology at TAU's Sackler Faculty of
Medicine, in collaboration with Sackler graduate student Adva Hadar and Prof. Haim Werner of TAU's Sackler Faculty of
Medicine, along with
researchers in Italy and Germany.
The study, led by
researchers at Boston University School of
Medicine (BUSM), reports sporadic mutations in the APC / C protein complex, specifically in the essential protein component Cdh1, which may predispose
humans to developing melanoma from the loss of the APC / C protein complex.
For years, Paul Shaw, PhD, a
researcher at Washington University School of
Medicine in St. Louis, has used what he learns in fruit flies to look for markers of sleep loss in
humans.
«
Researchers ID cancer gene - drug combinations ripe for precision
medicine: Yeast,
human cells and bioinformatics help develop one - two punch approach to personalized cancer therapy.»
In a screen of more than 100,000 potential drugs, only one, harmine, drove
human insulin - producing beta cells to multiply, according to a study led by
researchers at the Icahn School of
Medicine at Mount Sinai, funded by JDRF and the National Institutes of Health, and published online in Nature
Medicine.
It's usually used as livestock feed, but wheat bran's value in
human nutrition and
medicine may soon reach its full potential with a new sustainable processing method developed by Swedish
researchers.
In a novel animal study design that mimicked
human clinical trials,
researchers at University of California, San Diego School of
Medicine report that long - term treatment using a small molecule drug that reduces activity of the brain's stress circuitry significantly reduces Alzheimer's disease (AD) neuropathology and prevents onset of cognitive impairment in a mouse model of the neurodegenerative condition.
The
researchers, who reported their findings in a recent issue of BMC Complementary and Alternative
Medicine, suggest that the findings could pave the way for clinical testing of the compounds on
human colon cancer, which is the second most common cancer in women and the third in men.
Researchers found 53 existing drugs that may keep the Ebola virus from entering human cells, a key step in the process of infection, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and the National Institutes of Health (NIH), and published today in the Nature Press journal Emerging Microbes and
Researchers found 53 existing drugs that may keep the Ebola virus from entering
human cells, a key step in the process of infection, according to a study led by
researchers at the Icahn School of Medicine at Mount Sinai and the National Institutes of Health (NIH), and published today in the Nature Press journal Emerging Microbes and
researchers at the Icahn School of
Medicine at Mount Sinai and the National Institutes of Health (NIH), and published today in the Nature Press journal Emerging Microbes and Infections.
Researchers at University of California, San Diego School of
Medicine have induced this all - too - common
human experience — or a close version of it — permanently in rats and from what is observed perhaps derive clues about why strokes and Alzheimer's disease can destroy a person's sense of direction.
While genetics play a role in the development of Lupus, a systemic autoimmune disease that can attack any organ system in the
human body, so do environmental triggers, such as particulates in air pollution and ultraviolet light, explains Gaurav Gulati, MD, a physician -
researcher at the University of Cincinnati (UC) College of
Medicine.
In a study that has implications for
humans with inflammatory diseases,
researchers from Case Western Reserve University School of
Medicine and colleagues have found that, given over a six - week period, the artificial sweetener sucralose, known by the brand name Splenda, worsens gut inflammation in mice with Crohn's - like disease, but had no substantive effect on those without the condition.
Researchers from Boston University School of
Medicine (BUSM) and collaborators exposed miniature
human small intestines that they were able to grow in a dish (organoids) to the bacteria ETEC in the presence and absence of the protein histatin - 5.
But in July
researchers published a paper in the New England Journal of
Medicine that describes a well - designed, randomized, controlled study of
human nutrition — with surprising results.
Dr. Spangenburg and colleagues, including
researchers from the University of Maryland School of
Medicine, Brigham Young University, Karolinska Institutet in Sweden, and East Carolina University, found that the BRCA1 protein exists in both mouse and in
human skeletal muscle.
An international team of
researchers from NASA Ames Research Center, Environmental and Radiation Health Sciences Directorate at Health Canada, Oxford University, Canadian Nuclear Laboratories, Belgian Nuclear Research Centre, Insilico
Medicine, the Biogerontology Research Center, Boston University, Johns Hopkins University, University of Lethbridge, Ghent University, Center for Healthy Aging and many others have published a roadmap toward enhancing
human radioresistance for space exploration and colonization in the peer - reviewed journal Oncotarget.
The study, appearing in JAMA Internal
Medicine, was conducted by
researchers at NIH's Eunice Kennedy Shriver National Institute of Child Health and
Human Development (NICHD) and other institutions.
Researchers from Kent State University's College of Arts and Sciences, along with colleagues from the George Washington University, Yerkes National Primate Research Center, Georgia State University, Barrow Neurological Institute and the Icahn School of
Medicine at Mount Sinai, found that the brains of aged chimpanzees, our closest living relatives, show pathology similar to the
human Alzheimer's disease brain.
A study coming out in Science Translational
Medicine and led by University of Pennsylvania School of Veterinary
Medicine researchers has shown that cats with NPC — which mirrors the
human version of the disease — show vast improvements when treated with a compound called cyclodextrin.
To find out if these
medicines had the same effect on
humans, the
researchers at Harvard University started to collaborate with the Norwegian research team, and their unique resource of having access to the unique and large Norwegian database, where all Norwegian prescriptions are registered.
«By means of basic research on model organisms, we are trying to understand
human genome instability to identify elements, which, in the future, might be able to be explored as targets of new anti-tumour
medicines,» explains the
researcher responsible for the project and director of Cabimer, Andrés Aguilera.
The National Academies of Sciences, Engineering, and
Medicine (NAS) in Washington, D.C., yesterday held the first public meeting of a new committee of academic and industry
researchers, tasked with forecasting what biotechnologies will emerge in the next 5 to 10 years, and what new types of risk they might pose to the environment or
human health.
To detect NAFLD earlier and more easily,
researchers in the NAFLD Research Center at University of California San Diego School of
Medicine,
Human Longevity, Inc. and the J. Craig Venter Institute report that the unique microbial makeup of a patient's stool sample — or gut microbiome — can be used to predict advanced NAFLD with 88 to 94 percent accuracy.
The finding, by
researchers at the University of Illinois at Chicago College of
Medicine, was reported July 16 at the Alzheimer's Association International Conference in Copenhagen by Mary Jo LaDu, who in 2012 developed a transgenic mouse that is now regarded as the best animal model of the
human disease.
And
researchers at Stanford University School of
Medicine report in Genome Research that they linked the evolution of a gene in the old platypus to a mutated version in
humans responsible for moving the testes outside of the body and into an external pouch, or scrotum.
«
Researcher developing portable method to detect tainted
medicines, supplements: United Nations
Human Rights Council safe -
medicines resolution motivates research.»
Researchers at University of California San Diego School of
Medicine have discovered evidence in mice and
humans that stomach (gastric) acid suppression alters specific gut bacteria in a way that promotes liver injury and progression of three types of chronic liver disease.