Sentences with phrase «human mesenchymal stem cells»

Differences between in vitro viability and differentiation and in vivo bone - forming efficacy of human mesenchymal stem cells cultured on PCL - TCP scaffolds.

7000 compounds were tested on human mesenchymal stem cells carrying Type 1 myotonic dystrophy.

[3] H. Lin et al., «Influence of decellularized matrix derived from human mesenchymal stem cells on their proliferation, migration and multi-lineage differentiation potential,» Biomaterials, 33:4480 − 9, 2012.

Then, to boost the number of cells, which is another hurdle in tissue engineering, the researchers mixed the chondrocytes with human mesenchymal stem cells from bone marrow.

Multilineage potential of adult human mesenchymal stem cells.

Identification of common pathways mediating differentiation of bone marrow - and adipose tissue - derived human mesenchymal stem cells into three mesenchymal lineages.

It also provides novel insight into human mesenchymal stem cell - heart cell interactions that can guide future experimental studies to understand the mechanisms underlying mesenchymal stem cell therapy for the heart.

Morphological and immunocytochemical characteristics indicate the yield of early progenitors and represent a quality control for human mesenchymal stem cell culturing.

Human mesenchymal stem cells modulate allogeneic immune cell responses.

Fernando Ugarte Verdugo (Roesen - Wolff, TUD)-- «Role of Notch signalling pathway in human mesenchymal stem cell differentiation» (2009)

They next seeded each scaffold with three million commercially available human mesenchymal stem cells, which can give rise to bone, cartilage, fat and other tissues.

This has motivated novel cardiotherapeutic strategies to repair and regenerate heart muscle, including human mesenchymal stem cell (hMSC) therapy.

Scientists use mathematical modeling to simulate human mesenchymal stem cell delivery to a damaged heart and found that using one sub-set of these stem cells minimises the risks associated with this therapy.

Their computer simulations demonstrate that one family of human mesenchymal stem cells minimizes disturbances in cardiac single - cell and tissue level electrical activity.

Tufts University biomedical engineers recently published the first report of a promising new way to induce human mesenchymal stem cells (or hMSCs, which are derived from bone marrow) to differentiate into neuron - like cells: treating them with exosomes.

A new study, however, provides insights on the cellular mechanisms that might be targeted to help certain stem cells - called human mesenchymal stem cells (hMSCs)- maintain properties needed to make them clinically useful.

Researchers discover that a combination of pesticides at low concentrations can detrimentally affect human mesenchymal stem cells

Cell contact, prostaglandin E (2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4 + CD25 (High) forkhead box P3 + regulatory T cells.Clin Exp Immunol 2009; 156: 149 - 160.

Since 2005 his group is working on the immunomodulatory activities of human mesenchymal stem cells isolated from different sources — bone marrow, adipose tissue, endometrium, decidua.

Nanofiber orientation and surface functionalization modulate human mesenchymal stem cell behavior in vitro.

ISL1 overexpression enhances the survival of transplanted human mesenchymal stem cells in a murine myocardial infarction model.

Dr. Masayo Yumoto, team leader of Regenerative Medicine Research & Planning Division, Rohto Pharmaceutical Co., Ltd., has been holding a leadership role in the joint research lab at the Institute of Medical Sciences, University of Tokyo, to develop next generation cell culture method using human mesenchymal stem cells.

Here, authors from Corning Life Sciences describe dissolvable microcarriers as a scalable solution for large - scale expansion and harvest of functional human mesenchymal stem cells by enabling simplified downstream processing and high - yield cell recovery.

In an effort to improve this, we employed an alginate encapsulation strategy for human mesenchymal stem cells (hMSCs) and attached them to the heart with a biocompatible PEG hydrogel patch in a rat MI model.

Xuri cell culture media are formulated for the growth and expansion of human mesenchymal stem cells after their isolation from a number of sources.

Prof. Dr. Ivan Martin's research group at the Department of Biomedicine has now been able to demonstrate that by forcing certain molecular events occurring during the embryonic development of articular cartilage it is possible to generate stable cartilage tissue from adult human mesenchymal stem cells.

Differential osteogenicity of multiple donor - derived human mesenchymal stem cells and osteoblasts in monolayer, scaffold - based 3D culture and in vivo.

Characterization and functionality of cell surface molecules on human mesenchymal stem cells.

By identifying the benefits of using this specific sub-set of human mesenchymal stem cells this research may enhance safety for heart attack patients receiving stem cell therapy.

«The resulting hydrogel composed of physically self - assembled CarHC polymers exhibited a rapid gel - sol transition on light exposure, which enabled the facile release / recovery of 3T3 fibroblasts and human mesenchymal stem cells (hMSCs) from 3D cultures while maintaining their viability.»

Clough et al. first considered responses of human mesenchymal stem cells (hMSCs) present in the BM to the GSK3β - inhibitor (2 ′ Z, 3 ′ E)-6-bromoindirubin-3 ′ - oxime (BIO) at a concentration of 800 nM, given that hMSCs represent presumptive precursors of osteoblasts.

Ihor Zahanich (Ravens, TUD)-- «Differentiation potential of human mesenchymal stem cells: expression of molecular markers, ion channels and gap junction channels» (2006)

[2] S. Zeitouni et al., «Human mesenchymal stem cell - derived matrices for enhanced osteoregeneration,» Sci Transl Med, 4:132 ra55, 2012.

Bartosz Balana (Ravens, TUD)-- «Influence of culture conditions on differentiation and bioelectrical properties of human mesenchymal stem cells» (2005)

Human mesenchymal stem cells (hMSCs) are currently the most common adult stem cell type used for cell therapy applications due to their regenerative properties and ability to differentiate into multiple cell lineages (adipocyte, chondro ¬ cyte, and osteocyte).

Human mesenchymal stem cells (hMSCs) have become a popular potential therapy for numerous autoimmune and neurological disorders.