Sentences with phrase «human microglial»
S - but not R - enantiomers of flurbiprofen and ibuprofen reduce human microglial and THP - 1 cell neurotoxicity.
http://mcgeerandassociates.ca/ Not exact matches
Recently, thanks to major advances in human genetics, it has become increasingly clear that not only APOE and cholesterol metabolism, but also the proper functioning of microglial cells, strongly modulates the risk of developing AD in old age.
«Of course, it is not known when aging - associated changes in microglial activities begin in the human brain, but these results in mice suggest that it may be earlier than we had previously appreciated,» Watters says.
Researchers have now been able to show that Aducanumab, a human monoclonal antibody, selectively binds brain amyloid plaques, thus enabling microglial cells to remove the plaques.
Klegeris, A. and McGeer, P.L. Chymotrypsin - like proteases contribute to human monocytic THP - 1 cell, as well as microglial neurotoxicity.