Sentences with phrase «human myeloid»
Tumor necrosis factor - alpha inhibits hTERT gene expression in human myeloid normal and leukemic cells
https://www.cambridge.org/
His lab has made contributions in the area of tumor induced immunosuppression of dendritic cells, characterization of human myeloid derived suppressor cells, and the development of novel adjuvants for cancer vaccines.
Induction of Differentiation and Cellular Manipulation of Human Myeloid HL - 60 Leukemia Cells.
In mice implanted with human myeloid leukemia tumors, RHT greatly inhibited the tumors» growth and suppressed glucose uptake, similar to the effects seen in vitro.
Next - generation NSG models that support human myeloid cell proliferation, such as the NSG - SGM3 mouse, can now provide in vivo conditions that better mimic the natural tumor environment.
Not exact matches
That's how Charles Sawyers, a 2009 Lasker Award winner and chair of human oncology and pathogenesis at Memorial Sloan - Kettering Cancer Center in New York City, made the connection with Bristol Myers Squibb (BMS) that led to second - generation treatments for chronic myeloid leukemia (CML).
«We are now investigating chromosome fragile site formation in various human cell lines, including the chronic myeloid leukemia and Fragile X cells,» said Feng.
Recombinant human granulocyte colony - stimulating factor: effects on normal and leukemic myeloid cells.
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell.
«Remissions of Acute Myeloid Leukemia and Blastic Plasmacytoid Dendritic Cell Neoplasm Following Treatment with CD123 - Specific CAR T Cells: A First - in - Human Clinical Trial» is presented at the ASH Annual Meeting Dec. 9 to 12, 2017.
Locafaro G *, Andolfi G *, Russo F, Camisa B, Ciceri F, Bondanza A, Roncarolo MG *, Gregori S. HLA class I - dependent targeting of myeloid leukemia by IL -10-engineered human CD4 + Tr1 cells.
Tags: Acute Myeloid Leukemia, Andrew Hsieh, Basic Sciences, Clinical Research, Harmit Malik, Human Biology, Jesse Bloom, Marie Bleakley, Prostate Cancer, Transplant and Immunotherapy, Tumor specific translational research, Vaccine development - Viral cancers
Notch - mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution.
Tags: Acute Myeloid Leukemia, Anne McTiernan, cancer prevention, Computational Biology, exercise, genetic mutation, Harlan Robins, Human Biology, Lung Cancer, national science foundation, obesity, Pancreatic Cancer, physical activity, Public Health Sciences, stand up to cancer, Tumor specific translational research
Furthermore, we found that human IL - 15 mediated insulin - like growth factor - 1 production in CD215 + myeloid cells and blocking IGF - 1 reduced the tumor - promoting effect of IL - 15.
The project «Preprogrammed versus stochastic clonal evolution of relapsing Acute Myeloid Leukaemia: Impact on disease development and therapeutic responses» will dissect why the subpopulations of primary human blood cancer cells that drive leukaemic relapse resist relevant clinical treatments in vivo.
Although the National Toxicology Program said formaldehyde is «known to be a human carcinogen» in 2011, after studies linked it to cancers of the nose and myeloid leukemia, that research looked at manufacturing and funeral industry workers, who are exposed to higher levels of the substance than the general population, explains Laura Beane Freeman, PhD, an epidemiologist at the National Cancer Institute.
These flavonoids have almost no toxicity to human normal epithelial, peripheral and myeloid cells.
Mice and human volunteers who underwent cycles of the Fasting Mimicking Diet had decreased numbers of myeloid cells, the inflammatory immune cells that become more numerous as we age, and increased numbers of cytotoxic T cells, which protect the body against viruses and cancer.