Not exact matches
Working with
human breast tissue, the new study's authors attempted to induce EMT in
normal cells; they figured they would just get fibroblasts, a type of connective
tissue that is important in wound healing.
They compared
normal, non-cancer-forming
human breast tissue cells with cancerous
breast cells using both of these treatments, contrasting them with cells with unmanipulated mtDNA.
Using cutting - edge techniques enabled by next - generation sequencing, the authors generated complete methylome maps at single nucleotide resolution in a low - passage
breast cancer cell line and
normal breast tissue (primary
human mammary epithelial cells).
Rudensky's team compared Tregs in
normal human breast tissues with those found in untreated
breast tumors, and found that Tregs in tumors were capable of more potent and aggressive immunosuppressive action.
Tamoxifen and flaxseed alter angiogenesis regulators in
normal human breast tissue in vivo.