Working with animal patients is not the same as working with
human patients because of the vastly different biomechanics of the quadruped.
One thing that ran up a red flag was this: Zofran, one of the drugs listed for «herding dog» research, is rarely given to
human patients because of its astronomical cost.
The biology of laryngeal diseases is difficult to study from
human patients because access to the organ is difficult, and biopsy is inherently detrimental.
Not exact matches
Some
patients may even prefer to speak to bots like Woebot — «your charming robot friend who is always ready to listen» —
because it's less complicated than speaking to another
human being.
This message is the most important one
because it counterbalances those very
human moments when I am not the most
patient mom, they know how I really feel so that when I apologise for being angry or disappointing them or for making very
human mistakes they believe it
because they have seen through my words and most of my actions that I mean it.
Neonatologists who care for the tiniest and most fragile
patients use donor
human milk
because it provides immunologic and growth factors as well as optimal nutrition.
And in none of these conversations did anyone even suggest that they made a medical decision
because of money (in fact my sister actively avoids over-doing tests, etc even though she knows she could be making more money), nor do they suggest the
patient is anything less than a feeling
human being.
He says his team is so confident with its results that it plans to petition the Food and Drug Administration this fall to test isradipine's effectiveness in
human Parkinson's
patients,
because the drug has already been approved for
human use.
It typically takes many years to initiate such trials
because of the stringent safety testing that must be done before testing in
humans begins, but Reynolds said it may be possible to move faster as the therapy only involves modifying a
patient's dietary intake and supplementing with a medium - chain triglyceride oil, both of which have no known side effects.
The authors said that this result suggests that the reason bacterial numbers are so high in these mice, and, by extension,
human LAD
patients, is not
because of a defect in the immune system's surveillance mechanism but
because of the inflammation caused by the immune system's abnormal response to normal levels of bacteria in the gums.
«These results are especially exciting
because they show that we can take findings in the mouse and possibly apply them at the
human patient population,» said Koenig.
To see if PGD and the pentose phosphate pathway were tied to the epigenetic changes the researchers had detected in distant metastases, they treated tumor cells from different sites in a single
patient with the drug 6 - aminonicotinamide (6AN), which is known to inhibit PGD but is not used in
humans because of its severe side effects.
Because of the similarities in ocular anatomy, canine models contribute significantly to the understanding of retinal disease mechanisms and the development of new therapies for
human patients.
For example, although early clinical trials of Listeria - based vaccines have shown that the neutralized bacterium produces only mild flulike symptoms in
human patients with cervical cancer, the various methods of genetically disarming the bacteria should be explored to find the safest approach for people gravely ill with pancreatic cancer,
because these
patients are likely to already have weak immune systems.
Diagnoses become more objective
because patients no longer have to depend solely on
human observation.
Unfortunately,
because human genomes differ from one another, the use of a reference genome generated from one person in the process of diagnosing a different person can mask the true genetic changes responsible for a
patient's condition.
Triple - negative cancers are so called
because they do not express receptors for the hormones estrogen and progesterone, nor for HER2 (
human epidermal growth factor 2), and hence
patients with these cancers are not candidates for treatment with modern hormonal therapies or the highly effective HER2 - targeted drug Herceptin (trastuzumab).
The dogs were chosen
because they have inherited a genetic disease caused by the same gene defect as some
patients with
human retinitis pigmentosa.
No, Miller explained,
because that would violate the
patient's freedom to choose, which is fundamental to
human dignity.
She ultimately chose to study leukemia
patients» immune responses to bone marrow transplants, an area conducive to translational research in part
because the work involves treating
patients with
human cells, which can be prepared at academic health centers.
Because these receptors are mainly found deep inside the
human lung,
patients developed very severe illness that frequently left them too sick to spread SARS to many others; the people most at risk were health care workers who take care of
patients.
That's
because they may have finally developed a tissue model for the
human heart that can bridge the gap between animal models and
human patients.
In the current study, the researchers report the success of the BASILICA procedure in seven gravely ill
patients who qualified for compassionate use of the technique — then untested in
humans —
because no other care options were available.
Doctors should be on the lookout for
human patients, the researchers say,
because they might go undetected.
A clinical trial in
humans of a vaccine based on Ab antibodies was halted in 2002
because 5 percent of the
patients developed encephalitis.
The lawsuit against Myriad Genetics and the University of Utah Research Foundation, which hold the patents on the genes, charged that the challenged patents are illegal and restrict both scientific research and
patients» access to medical care, and that patents on
human genes violate the First Amendment and patent law
because genes are «products of nature.»
Because myostatin normally acts to limit muscle growth, there has been considerable interest in targeting this pathway to attempt to enhance muscle growth in
human patients with muscle wasting and muscle degenerative diseases.
And, while the genetically - modified mice were made somewhat better by deactivating the HD gene in their hypothalamus, this approach isn't useable in
human HD
patients because their HD genes don't contain the sequences needed to turn them off with virus used by Petersen and colleagues.
The research is significant for
humans, said Baranzini,
because the presence or absence of Tob1 in CD4 + cells could eventually serve as a prognostic biomarker that could help clinicians predict the course and severity of MS in individual
patients.
But the approach used to reduce «depression» in the mice is not useful for
human HD
patients,
because it relies on genetic tricks that only work in the BAC - HD mice.
In
humans,
because invasive studies are not ethically permissible except in some neurological
patients, by far the largest number of EEG studies have been conducted using electrodes glued to the scalp.
«This is hard to do in a standard
human clinical study where one compares
patients with a history of smoking versus those who do not smoke
because all of the
patients have different histories, backgrounds and patterns of exposure to the stimulus.»
There are lots of different HD mice available, and
because every case of HD is caused by the same basic genetic mutation, it may be that «our» mice will turn out to be better than those of other diseases, at predicting success in
human patients.
Because humans are born with a stable population of RPE cells that stay put throughout life, the researchers expected that fixing the cells once would make a lasting impact — and indeed, the vision of
patients who got the therapy improved after a single treatment.
Because is hard to predict who will develop the disease,
human studies typically occur after
patients are quite sick.
The study protocol was approved by the KPNC institutional review board and the California State Committee for the Protection of
Human Subjects, which waived written consent for participants
because our data - only study had no direct contact with
patients.
The lab chose to use the TCL1 mouse model to study B - cell leukemia
because ~ 90 percent of
human chronic lymphocytic leukemia (CLL)
patients express the TCL1 protein, and the overexpression of TCL1 in B cells leads to the development of CLL in mice.
Because prions have a long incubation period, even 30 to 40 years after the practice of using
human cadaveric hormones was stopped,
patients who received those treatments continue to show signs of CJD.
He tested his theory in several experiments with lab animals and
humans and developed quite a following
because of the clinical success with his
patients.
(Chlorella, January 19th, 2012)
Because it is believed that a powerful phytochemical found in chlorella can even rebuild nerve damage in
human brain and nervous system chlorella is being often used in the recovery of
patients with Parkinson's and Alzheimer's disease.
Unfortunately, there are no guarantees in
human or veterinary medicine with any medical or surgical treatment
because the ultimate outcome of any medical or surgical therapy depends on the response of the
patient receiving treatment.
«I was really excited to hear about their work
because the cat disease behaved very similarly to what I saw in my
human patients with oral lichen planus,» Fazel said.
In
human health, in many cases the
patient is not bearing the brunt of the cost
because they have some sort of third - party payer insurance, whether that be private insurance or government - provided insurance like Medicaid and Medicare.
«I like working here
because I am able to be involved with both animals and
humans through our team, clients, and
patients,» she says.
Veterinarians largely agree to not use Vancomycin or linezolid (Zyvox) in
patients because it is reserved as a
human rescue drug.
Because one year in an older cat's life is equal to roughly five years in a
human's, we recommend that our older
patients come in at least twice a year for a physical exam, weight check, and thorough discussion of «how your cat is doing at home.»
Because the
patient cooperates, dental scaling of
human teeth performed by a professional trained in the procedures can be completed successfully without anesthesia.
Your hospital offers the best veterinary care available
because of your incredible staff, from the care each and every
patient receives to the kindness shown to their
humans who entrust their pets» lives to you.
VetFolio reports the routine use of antibiotics is considered to be of no benefit in animals with pancreatitis
because, in contrast to
human pancreatitis
patients, bacteria do not seem to play a role in pancreatitis in small animals.
Although, in
human medicine,
patients may receive a «placebo effect»
because they often expect that the treatment will be successful.