Sentences with phrase «human phenotype data»

Not exact matches

Since 2007, the GWAS policy has governed biomedical researchers» submission and access to human data through the NIH database for Genotypes and Phenotypes (dbGaP).

The IMI could also control and organize access to metadata (the associated host disease phenotype data, for a human gut microbiota sample, for instance) without which meaningful interpretation of the data is not possible.

Harmonising ontological descriptions of phenotype in mouse and human and improving links between mouse model data and human data, using diabetes and obesity as examples, will increase the relevance of data that is generated in mouse studies for clinical studies.

The Human Phenotype Ontology project: linking molecular biology and disease through phenotPhenotype Ontology project: linking molecular biology and disease through phenotypephenotype data.

For example, 2013 saw studies showing that transplanting human fecal microbiota into mice could induce obesity and its associated metabolic phenotypes, and human data from a controlled study suggesting the procedure could treat recurrent C. difficileinfection.

Test each mutant mouse line (4,000 mouse lines in the first 5 years, and ultimately up to 20,000) through a broad based primary phenotyping pipeline in all the major adult organ systems and most areas of major human diseases.Through this activity and employing data annotation tools, systematically aim to discover and ascribe biological function to each gene, driving new ideas and underpinning future research into biological systems.

He is currently head of the Ensembl project and has held leadership roles in data management activities for the 1000 Genomes Project, the International Human Epigenome Consortium (IHEC) and the International Mouse Phenotyping Consortium (IMPC).

Having investigated the different representations of phenotypes, she applies this knowledge to data integration and human genetic disorders with the aim of improving the understanding about the molecular mechanisms underlying human diseases.

This work package is aimed at harmonising ontological descriptions of phenotypes in mouse and human, consequently improving the links between mouse and human data.

Research that provides human data and does the following is assigned the highest priority: â $ cents Evaluate the protective effect of fiber against colon cancer in subsets of the population by applying genotyping and phenotyping to those par - ticipating in fiber and colon cancer trials.