Sentences with phrase «human phosphatidylserine»
«This means, in conjunction with our previous research papers, that Ebola virus VP40 can assemble and interact with human phosphatidylserine to generate the lipid coat of the virus,» Stahelin said.
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It interacts with a human plasma - membrane lipid, phosphatidylserine, to facilitate replication of the virus.
Stahelin and co-investigator Smita Soni, a postdoctoral researcher at the Indiana University School of Medicine, found that VP40 is able to assemble in vitro (i.e., in a test tube), without any human cells present and mediate formation of virus - like particles when the human lipid phosphatidylserine is found in solution with VP40, but not other control lipids.
Using standard enzyme - linked immunosorbent assays (ELISA) and peripheral blood mononuclear cell (PBMC) assays, researchers discovered that unlike previously described human antibodies to lipids, WR321 did not react with any of 17 other lipids it was tested against, including cholesterol, glycolipids, and other phospholipids such as cardiolipin and phosphatidylserine, but it bound specifically only to two phosphoinositides.
Effects of phosphatidylserine on the neuroendocrine response to physical stress in humans.
Based on human and animal research, it appears a variety of nutritional and botanical substances — such as adaptogenic herbs, specific vitamins including ascorbic acid, vitamins B1 and B6, the coenzyme forms of vitamin B5 (pantethine) and B12 (methylcobalamin), the amino acid tyrosine, and other nutrients such as lipoic acid, phosphatidylserine, and plant sterol / sterolin combinations — may allow individuals to sustain an adaptive response and minimize some of the systemic effects of stress.
Based on human and animal research, it appears a variety of nutritional and botanical substances - such as adaptogenic herbs, specific vitamins including ascorbic acid, vitamins B1 and B6, the coenzyme forms of vitamin B5 (pantethine) and B12 (methylcobalamin), the amino acid tyrosine, and other nutrients such as lipoic acid, phosphatidylserine, and plant sterol / sterolin combinations - may allow individuals to sustain an adaptive response and minimize some of the systemic effects of stress.