It is lethal to frogs and highly toxic to
human placental cells, even at one - tenth the recommended dosage.
Additionally, sex differences were recently also described in the transcriptome of
human placental cells, demonstrating an influence of fetal sex on placental gene expression in a cell - type dependent manner (186).
Human placental cell line Jeg - 3 can be readily infected by a circulating strain of Zika virus (left panel) and completely protected by treatment with nanchangmycin (right panel).
Not exact matches
Some scientists study
cells, called primary
human trophoblasts, that are isolated from placentas obtained after childbirth, but such
cells do not divide, can be more difficult to obtain, and are more difficult to genetically manipulate to learn about biochemical pathways that have a role in
placental function, Dr. Coyne said.
«You'd still have to ration the therapy,» cautions Robert Hariri, chief researcher at Anthrogenesis in Cedar Knolls, New Jersey, which announced this year that it had morphed
human placental stem
cells into nerve, blood, cartilage, skin, and muscle
cells.
A 10 µl of probe hybridization mix was prepared by mixing 100 ng XMRV - SO, 100 ng CEP8 - SA, 1000 ng sonicated
human placental DNA, 250 ng
human Cot - 1 DNA, and 7 µl LSI / WCP hybridization buffer (Abbott Molecular, Inc.), and was added to each slide over the
cell specimen.