Sentences with phrase «human prostate»
The phrase "human prostate" refers to a small gland found only in males that is part of the reproductive system. It produces the fluid that nourishes and transports sperm. Full definition
The lab used a series of human prostate cancer cells, representing different stages of prostate cancer and showed that all the stages responded to this compound.
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The researchers have yet to show the same pathway is active in human prostate cancers.
The new findings show that human prostate tissue is also susceptible.
In both laboratory dishes and mice with human prostate cancers, the nanoparticles proved extremely effective.
FRESH insight into prostate cancer has come in a study showing that the mitochondrial DNA of human prostate cancer cells is riddled with mutations.
In preclinical experiments using human prostate cancer cell lines, Fu's team showed that increased PLK1 expression activated an oncogene known as c - RAF, which has previously been shown to play a role in regulating cell growth and division.
Dr. Steven R. Goodman, Editor - in - Chief of Experimental Biology and Medicine, said «This study by Huanbiao Mo and colleagues at the Texas Woman's University and UT Southwestern Medical Center demonstrates that geranylgeraniol causes dose dependent apoptotic death of human prostate carcinoma cells.
Importantly this article suggests that geranylgeraniol deserves further study as a potential therapy for human prostate cancer.»
To determine if there was a link in humans, Prins developed a new animal model using human prostate stem cells implanted into mouse «hosts.»
Coffin described how lab workers there had transplanted human prostate tumor cells into an immune - deficient lab mouse, a common procedure for procuring a colony of cells, or a human cell line, for further study.
«Effect of whey protein isolate on intracellular glutathione and oxidant - induced cell death in human prostate epithelial cells.»
Expression of RANKL / RANK / OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation.
Protein analysis of human prostates also detected CD117 + protein.
[5] Another study found that one of the antioxidants in spinach slowed prostate cancer in animal as well as human prostate cancer cells.
Researchers concluded that capsaicin has a serious anti-proliferative action upon human prostate type of cancer cells within culture.
Introducing human prostate cancer cell lines into mice, Wu and his colleagues saw a particular enzyme called MAOA activate a cascade of signals that made it easier for tumor cells to invade and grow in bone.
The loss of CHD1, one of the most frequently mutated genes in prostate tumors, sensitizes human prostate cancer cells to different drugs, including PARP inhibitors.
It also shrank human prostate cells by 21 per cent.
In mice, the treatment made aggressive human prostate cancer tumours virtually disappear within days.
Prins investigated the effect of BPA on human cells by implanting human prostate stem cells taken from deceased young - adult men into mice.
Tadashi Matsuda of Hokkaido University and his colleagues in Japan investigated human prostate cancer cells to determine if there is an unknown up - regulation mechanism in the EGFR pathway.
As recent data suggest, PSMA is an important cancer antigen expressed on many human prostate, bladder, renal as well as ovarian cancers, so additional study of the possible benefits of this therapy are important.»
Immunohistochemical analysis of paraffin - embedded human prostate carcinoma using unpurified ab32518 at 1/50 dilution.
Immunohistochemical staining of paraffinembedded human prostate cancer using P2RX7 antibody (11144 -1-AP) at a dilution of 1:50 (10x objective).
Preclinical efficacy of growth hormone - releasing hormone antagonists for androgen - dependent and castration - resistant human prostate cancer.
On the basis of studies on the XMRV - producing human prostate cancer cell lines CWR22Rν1 and CWR - R1 and their progenitor tumour xenograft CRW22, they concluded that XMRV infections were caused by contamination during in vivo passaging in nude mice.
Our laboratory has been studying normal human prostate epithelial and prostate cancer stem and progenitor cells (27 — 29, 31 — 33).
The test involves aggregating human prostate cancer cells into microtissues in 96 - well plates and monitoring their growth over 90 days.
Here, using PC3 human prostate carcinoma cells as a model, we provide direct experimental evidence that tumor cell holoclones contain stem - like cells that can initiate serially transplantable tumors.
5alpha - androstane - 3alpha, 17 beta - diol supports human prostate cancer cell survival and proliferation through androgen receptor - independent signaling pathways: implication of androgen - independent prosta.
«BPA increases risk of cancer in human prostate tissue, study shows.»
«Our research provides the first direct evidence that exposure to BPA during development, at the levels we see in our day - to - day lives, increases the risk for prostate cancer in human prostate tissue,» Prins said.
A novel indium -111-labeled gonadotropin - releasing hormone peptide for human prostate cancer imaging.
Next, the researchers tested the effects of RK - 33 and radiation in mice that had been injected with human prostate cancer cells that highly express DDX3.
Species - specific homing mechanisms of human prostate cancer metastasis in tissue engineered bone.
A team of researchers in Germany and Denmark led by Steven Johnsen, Professor at the University Medical Center Göttingen, Germany, used human prostate cancer cell lines and depleted them of the DNA - binding protein CHD1.
Development of a bioengineered model to quantitatively measure the tumorigenic properties of cancer - associated fibroblasts in human prostate cancer.
«We think that the degradation of PTEN after loss or impairment of Importin - 11 is a very effective driver of human prostate cancer,» says Trotman.
«Plant oil suppresses viability of human prostate cancer cells.»
The researchers showed that cabazitaxel worked better than docetaxel in human prostate cancer cells lines that were resistant hormone treatment, both in terms of slowing cancer - cell growth and in its ability to kill cancer cells.
According to McCague, «the rarity of human prostate cancer cell cultures makes studying tamandron's potential difficult in the test tube.»
Signs of cancer developed in the human prostate tissue in a third of the mice fed BPA, as compared to only 12 percent in mice that had not been fed BPA.