Sentences with phrase «human prostate cancer»

The lab used a series of human prostate cancer cells, representing different stages of prostate cancer and showed that all the stages responded to this compound.

The researchers have yet to show the same pathway is active in human prostate cancers.

In both laboratory dishes and mice with human prostate cancers, the nanoparticles proved extremely effective.

«Capsaicin inhibits the growth of human prostate cancer cells in petri dishes and mice,» said lead researcher Dr. H. Phillip Koeffler, director of hematology and oncology at Cedars - Sinai Medical Center and a professor of medicine at the University of California, Los Angeles.

A novel indium -111-labeled gonadotropin - releasing hormone peptide for human prostate cancer imaging.

In preclinical experiments using human prostate cancer cell lines, Fu's team showed that increased PLK1 expression activated an oncogene known as c - RAF, which has previously been shown to play a role in regulating cell growth and division.

XMRV was initially isolated from the tissues of prostate cancer patients [1] and subsequently found to be present in 6 — 27 % of human prostate cancer cases [2].

The translational relevance of this study is supported by the analysis of human prostate cancer samples that showed upregulation of these three components of the pathway, which correlated with enhanced mTORC1 activation.

Expression of RANKL / RANK / OPG in primary and metastatic human prostate cancer as markers of disease stage and functional regulation.

Species - specific homing mechanisms of human prostate cancer metastasis in tissue engineered bone.

Introducing human prostate cancer cell lines into mice, Wu and his colleagues saw a particular enzyme called MAOA activate a cascade of signals that made it easier for tumor cells to invade and grow in bone.

The loss of CHD1, one of the most frequently mutated genes in prostate tumors, sensitizes human prostate cancer cells to different drugs, including PARP inhibitors.

In mice, the treatment made aggressive human prostate cancer tumours virtually disappear within days.

Tadashi Matsuda of Hokkaido University and his colleagues in Japan investigated human prostate cancer cells to determine if there is an unknown up - regulation mechanism in the EGFR pathway.

Immunohistochemical staining of paraffinembedded human prostate cancer using P2RX7 antibody (11144 -1-AP) at a dilution of 1:50 (10x objective).

Given annually to post-doctoral fellows who demonstrate original investigation and professional excellence in preparing scientific papers, Dr. Lee won second place in basic science for this publication: «Dysregulation of Cholesterol Homeostasis in Human Prostate Cancer through Loss of ABCA1» Lee BH, Taylor MG, Robinet P, Smith JD, Schweitzer J, Sehayek E, Falzarano SM, Magi - Galluzzi C, Klein EA, and Ting AH Cancer Res 2013 Feb 1; 73 (3): 1211 - 8 PMID: 23233737

The team analyzed 43 human prostate cancer tumors and found a higher proportion of low - PSA cells in more advanced tumors.

Preclinical efficacy of growth hormone - releasing hormone antagonists for androgen - dependent and castration - resistant human prostate cancer.

On the basis of studies on the XMRV - producing human prostate cancer cell lines CWR22Rν1 and CWR - R1 and their progenitor tumour xenograft CRW22, they concluded that XMRV infections were caused by contamination during in vivo passaging in nude mice.

The test involves aggregating human prostate cancer cells into microtissues in 96 - well plates and monitoring their growth over 90 days.

5alpha - androstane - 3alpha, 17 beta - diol supports human prostate cancer cell survival and proliferation through androgen receptor - independent signaling pathways: implication of androgen - independent prosta.

Importantly this article suggests that geranylgeraniol deserves further study as a potential therapy for human prostate cancer.»

Next, the researchers tested the effects of RK - 33 and radiation in mice that had been injected with human prostate cancer cells that highly express DDX3.

The researchers showed that cabazitaxel worked better than docetaxel in human prostate cancer cells lines that were resistant hormone treatment, both in terms of slowing cancer - cell growth and in its ability to kill cancer cells.

A team of researchers in Germany and Denmark led by Steven Johnsen, Professor at the University Medical Center Göttingen, Germany, used human prostate cancer cell lines and depleted them of the DNA - binding protein CHD1.

FRESH insight into prostate cancer has come in a study showing that the mitochondrial DNA of human prostate cancer cells is riddled with mutations.

[5] Another study found that one of the antioxidants in spinach slowed prostate cancer in animal as well as human prostate cancer cells.

«We think that the degradation of PTEN after loss or impairment of Importin - 11 is a very effective driver of human prostate cancer,» says Trotman.

«Plant oil suppresses viability of human prostate cancer cells.»

According to McCague, «the rarity of human prostate cancer cell cultures makes studying tamandron's potential difficult in the test tube.»

Early exposure to BPA (bisphenol A)-- an additive commonly found in plastic water bottles and soup can liners — causes an increased cancer risk in an animal model of human prostate cancer, according to University of Illinois at Chicago researcher Gail Prins.

The study profiled the lncRNAs in three distinct groups: (1) human prostate cancer cell lines and normal prostate epithelial cells, (2) prostate adenocarcinoma tissue samples and matched normal tissue samples, (3) urine samples from patients with prostate cancer or benign prostate hypoplasia, and normal healthy individuals.

11C - sarcosine also produced high - contrast images in a human prostate cancer case.

2013 Selective Targeting of CYP24A1 as a Rational Approach for Vitamin D3 Based Therapies in Human Prostate Cancer.

Although persistent loss of IGF - 1R expression ultimately induced cell stasis and death, both of these processes are regulated by the tumor suppressor gene p53 that is commonly mutated in human prostate cancers.

Androgen - regulated expression of arginase 1, arginase 2 and interleukin - 8 in human prostate cancer.

Development of a bioengineered model to quantitatively measure the tumorigenic properties of cancer - associated fibroblasts in human prostate cancer.

A bioengineered microenvironment to quantitatively measure the tumorigenic properties of cancer - associated fibroblasts in human prostate cancer.

The human prostate cancer cell line PC3, which was obtained from Scott Crist (Purdue University), was maintained in Roswell Park Memorial Institute - 1640 (RPMI - 1640) medium, containing 10 % fetal bovine serum, FBS (HyClone), and 1 % penicillin / streptomycin plus L - glutamine.

The DAXX co-repressor is directly recruited to active regulatory elements genome - wide to regulate autophagy programs in a model of human prostate cancer

Identification of differentially expressed genes by serial analysis of gene expression in human prostate cancer.

«Theranostics» Simultaneously Kill and Image Prostate Cancer Cells Experimenting with human prostate cancer cells and mice, cancer - imaging experts developed a method for finding and killing malignant cells while sparing healthy ones.