The lab used a series
of human prostate cancer cells, representing different stages of prostate cancer and showed that all the stages responded to this compound.
The researchers showed that cabazitaxel worked better than docetaxel
in human prostate cancer cells lines that were resistant hormone treatment, both in terms of slowing cancer - cell growth and in its ability to kill cancer cells.
In preclinical experiments
using human prostate cancer cell lines, Fu's team showed that increased PLK1 expression activated an oncogene known as c - RAF, which has previously been shown to play a role in regulating cell growth and division.
Introducing human prostate cancer cell lines into mice, Wu and his colleagues saw a particular enzyme called MAOA activate a cascade of signals that made it easier for tumor cells to invade and grow in bone.
On the basis of studies on the XMRV -
producing human prostate cancer cell lines CWR22Rν1 and CWR - R1 and their progenitor tumour xenograft CRW22, they concluded that XMRV infections were caused by contamination during in vivo passaging in nude mice.
5alpha - androstane - 3alpha, 17 beta - diol
supports human prostate cancer cell survival and proliferation through androgen receptor - independent signaling pathways: implication of androgen - independent prosta.
Naringenin, a flavonoid concentrated in grapefruit, helps repair damaged DNA
in human prostate cancer cells (cell line LNCaP), reports a lab study published in the Journal of Nutritional Biochemistry.
«Capsaicin inhibits the growth
of human prostate cancer cells in petri dishes and mice,» said lead researcher Dr. H. Phillip Koeffler, director of hematology and oncology at Cedars - Sinai Medical Center and a professor of medicine at the University of California, Los Angeles.
A team of researchers in Germany and Denmark led by Steven Johnsen, Professor at the University Medical Center Göttingen, Germany,
used human prostate cancer cell lines and depleted them of the DNA - binding protein CHD1.
«Theranostics» Simultaneously Kill and Image Prostate Cancer Cells Experimenting
with human prostate cancer cells and mice, cancer - imaging experts developed a method for finding and killing malignant cells while sparing healthy ones.
The study profiled the lncRNAs in three distinct groups: (1)
human prostate cancer cell lines and normal prostate epithelial cells, (2) prostate adenocarcinoma tissue samples and matched normal tissue samples, (3) urine samples from patients with prostate cancer or benign prostate hypoplasia, and normal healthy individuals.
FRESH insight into prostate cancer has come in a study showing that the mitochondrial DNA of
human prostate cancer cells is riddled with mutations.
«Plant oil suppresses viability of
human prostate cancer cells.»
The human prostate cancer cell line PC3, which was obtained from Scott Crist (Purdue University), was maintained in Roswell Park Memorial Institute - 1640 (RPMI - 1640) medium, containing 10 % fetal bovine serum, FBS (HyClone), and 1 % penicillin / streptomycin plus L - glutamine.