Today, yeasts are programmed to secrete
human proteins used in vaccines, insulin and other biopharmaceuticals.
Not exact matches
For example, instead of
using the
protein scissors to cut a virus, they can be
used to cut out DNA in a
human cell and replace it with DNA of the scientist's choosing.
What about some 2,000
proteins that are
used by a
human cell as enzymes?
«We
use non-GMO or organic soybeans, delivering
proteins for
human consumption that have been processed without any chemicals, with the bean producing as much of the
protein as possible,» Nadler says.
7) Public hearings must be held to investigate the effect the continued
use of
protein products derived from milk, including casein, milk
protein concentrate (MPC), ultra-filtered milk, etc. have had on the farm price for milk and the price consumers are paying for milk and dairy products and to determine safety and nutritional impacts of these
proteins on
human health.
The UK government's waste agency has said that alternative
protein sources will be needed for
humans and livestock to reduce land and energy
use.
The UK Government's waste agency has said that alternative
protein sources will be needed for
humans and livestock to reduce land and energy
use.
Dr. Jaeger and his co-author, Dr. Jacob Wilson (University of Tampa, Department of Health Sciences and
Human Performance),
used 24 healthy, college - aged, resistance - trained participants who consumed 48g of rice or whey
protein isolate immediately following training for 8 weeks.
A West L.A. company that is considered the world's largest wholesale supplier of brown rice
protein for
human consumption is
using the findings to expand its market.
IMPORT ALERT # 99 - 29 «Detention without physical examination of all vegetable
protein products from China for animal or
human food
use due to the presence of Melamine and / or Melamine Analogs»
If you don't feel comfortable
using donor breastmilk, goat's milk formula is a good option, as in terms of
protein structure, it's actually the closest mammalian milk to
human milk.
less than or equal to lamivudine Acquired Immune Deficiency Syndrome Antiretroviral therapy, usually means 1 - 2 drugs,
used in early studies Antiretroviral zidovudine (also known as ZDV) Breastfeeding Baby Friendly Hospital Initiative Breastfeeding and HIV International Transmission Study Combined antiretroviral therapy Centers for Disease Control and Prevention Deoxyribonucleic Acid Exclusive Breastfeeding Enzyme Linked Immunosorbent Assay Food and Agrigulture Organization Fixed dose combination ART, e.g., lamividine, stavudine, and nevirapine Highly Active Antiretroviral Therapy, 3 or more drugs for more effective treatment
used in later studies
Human Immunodeficiency virus International Atomic Energy Agency Infant feeding Infant and young child feeding Lopinavir cubic millimetre Mother - to - Child Transmission of HIV Non-governmental organization Nevirapine Polymerase Chain Reaction People Living with HIV Prevention of Mother - to - Child Transmission Replacement Feeding Ritonavir Ribonucleic acid, one of the three major macromolecules (along with DNA and
proteins) that are essential for all known forms of life single dose NVP United Nations Agencies Joint United Nations Programme on HIV / AIDS United Nations Population Fund United Nations Commissioner for Refugees United Nations Children's Fund U.S. Agency for International Development World Alliance for Breastfeeding Action United Nations World Food Programme World Health Assembly WHO 2010 Guidelines on HIV and infant feeding World Health Organization Zidovudine (same drug as AZT)
Using this new method, Lemay and colleagues identified 1,606
proteins in
human milk and 518
proteins in rhesus macaque milk.
CRISPR / Cas9 - mediated gene editing in
human zygotes
using Cas9
protein.
To that end, Oxford grad student Samantha Brown reported in a poster that she discovered a
human bone fragment by
using a new technique, called ZooMS, to scan 2315 bones from the cave for uniquely
human proteins.
Then a team of Chinese researchers
used that base editor to correct a mutation in
human embryos that causes the blood disorder beta - thalassemia, reported September 23 in
Protein & Cell (SN: 11/25/17, p. 7).
Using a mouse model that expresses an altered form of the normal
human prion
protein, researchers at University of California, San Diego School of Medicine have determined why the
human proteins aren't corrupted when exposed to the elk prions.
These findings allowed researchers to create a chimera virus: a mouse virus with a
human viral gene that can be
used to test molecules that inhibit
human LANA
protein in an animal model of disease, treating not only
human herpes virus infection but also its associated cancers.
Using viral gene insertion and regulatory
proteins, researchers turned adult
human skin cells directly into adult
human blood cells, without first returning them to a fully pluripotent state.
The «acid spit» chewed up surface
proteins that the pathogen
uses to attach to and invade
human cells.
The new drug - like compounds discovered by Vogel and her co-authors offer hope that
using a computer - generated P - gp model, explained here http://bit.ly/1LVmR7a, developed to accurately mimic the physical, chemical and biological functions of the
protein in the
human body, will speed up the drug discovery process and work in real life as well.
Building the knowledge base requires
humans to teach computers key concepts from curated articles; with modest online training, anyone who reads English can scan research papers for key terms — names of genes,
proteins, diseases, and drugs — and
use online marking tools to document relationships between them (for example, drug X treats disease Y).
Using human fetal «mini-brains» grown in 3 - D cultures, scientists determined that a specific
protein produced by the Zika virus changes the properties of neural stem cells in the developing brain of an infected fetus, potentially causing microcephaly in newborns (Ki - Jun Yoon, abstract 103.06, see attached summary).
«Since this
protein is not found in any mammal, it emerges as a good candidate for the development of novel thermogenetic tools to be
used for basic research and potentially one day in
humans.»
Scottish researchers took a similar approach to clone sheep that will produce in their milk
human factor IX
protein, which is
used to treat hemophilia.
In tests in mice, a vaccine developed
using human malaria parasite
proteins — known as MSP -1-BBM — enabled the immune system to produce antibodies in the bloodstream.
Vaccines developed
using proteins rather than live viruses can help protect animals and subsequently
humans from insect - borne viruses, according to Alan Young, chief scientific officer for Medgene Labs, an animal health company that develops therapeutics and diagnostics, including vaccines.
Using a genome - wide genetic screen, Dr. Gelman and colleagues identified a previously unknown metastasis suppressor — the FOXO4
protein, which belongs to a family of genes that are produced by all
human cells.
Bacteria can be genetically modified to produce various
proteins and other substances
humans need, so 3 - D printed bacterial materials may have many other medical
uses, too.
«All living organisms, including
humans, must continuously transport and redistribute molecules around their cells,
using vital carrier
proteins,» he said.
The research team
used molecular modeling and knowledge of hemagglutanin's structure to identify mutations that would change the
protein's amino acid sequence and cause a switch to
human specificity.
Marth is
using the simulation version of the
human body to examine the makeup and behavior of critical cell components, such as
proteins, lipids (fats) and glycans (sugars).
The team printed structures in a variety of materials, including collagen and fibrin — both structural
proteins found in the
human body — and a seaweed - derived substance called alginate that is widely
used as a thickening or structural agent in food, industry, and medicine.
Approaches based on these five strategies have been
used for streamlined, enhanced validation of more than 10,000 antibodies from more than 30 providers, targeting over 7,000
human proteins as part of the Human Protein Atlas pro
human proteins as part of the
Human Protein Atlas pro
Human Protein Atlas program.
To search for new enzymes that could repair telomeres, the researchers — Susan Smith, Titia de Lange, and their colleagues at Rockefeller University in New York City —
used a biochemical screen to find substances that interact with TRF1, a
human protein known to bind to telomeres.
Microbeads coated in a
human egg
protein work as a contraceptive in mice and could also be
used to select the best sperm for IVF
Medical treatment that targets
human proteins rather than ever - mutating viruses may one day help HIV - positive people whose bodies have built a resistance to «cocktails» currently
used to keep them healthy, according to a Keck School of Medicine of USC researcher.
First, the destabilizing effects of VX - 770 on the corrected CFTR
protein might be less robust in the
human body than were the effects seen in lab tests
using human lung cells.
«New way to treat HIV identified: Targeting
human proteins may be more effective than the
use of «HIV cocktails» to maintain health.»
The researchers
used «bait»
proteins from over two dozen known autism genes, fishing in a pool of
human DNA for other
proteins that would interact with the baits.
Chemical biologists hope a new Internet portal will improve information on small, druglike molecules that are
used to study
protein vital to
human health and disease.
The study «unambiguously shows that you can achieve a robust [
protein decrease] in
humans using RNAi therapeutics,» Kay sats.
To see whether cancer stem cell renewal involves a chain of events similar to that
used by embryonic stem cells, and whether the process was affected by oxygen levels, Semenza and graduate student Chuanzhao Zhang focused their studies on two
human breast cancer cell lines that responded to low oxygen by ramping up production of the
protein ALKBH5, which removes methyl groups from mRNAs.
In 2016, Collins and colleagues published evidence of
proteins on ostrich shells that were almost 4 million years old — the connection to
human evolution may not be readily apparent, but such shells have been
used by hominins for millions of years to transport water and other resources.
Mathias Uhlen, director of the
Human Protein Atlas project and co-author of the paper, says: «I am extremely pleased that the resource created through the
Human Protein Atlas effort has been
used in the analysis of clinical data obtained from liver disease patients and that this analysis has led to the identification of liver - specific drug targets that can be
used for treatment of this clinically important patient group.»
To track down the location of
proteins inside
human tissues, Uhlén's team of about 100 scientists breaks the problem into two parts — finding antibodies that target individual
proteins and then
using those antibodies to hunt for
proteins inside tissues.
Mardinoglu says the team's network modeling approach, which relied on data from the Sweden - based
Human Protein Atlas project and The Genotype - Tissue Expression (GTEx) project consortia, can be
used in the identification of drug targets and eventually in the development of efficient strategies for treating a number of chronic liver diseases.
Additional experiments
using a combination of maraviroc and a drug that blocks the VEGF
protein suggest that the treatment duo could be an effective way to prevent metastatic disease in
human breast cancer patients, according to the researchers.
While previous investigations into the
protein's effects have
used either mice in which gene expression was knocked out or transgenic animals that expressed
human gene variants throughout their lifetimes, the MGH - MIND - led study
used a different approach to investigate the effects of introducing the variant forms of the
protein into brains in which plaque formation had already begun.
Unique
protein markers in hair could be
used alongside DNA profiling for
human identification, according to a study published September 7, 2016 in the open - access journal PLOS ONE by Glendon Parker from Lawrence Livermore National Laboratory, USA, and colleagues.