Sentences with phrase «human proteome»

CDI utilizes its HuProt ™ Human Proteome Microarray for validating the specificity of the final product.
In order to localize the whole human proteome on a subcellular level in one specific cell line a third cell line, U-2 OS, is always chosen.
The CDI HuProt human proteome microarray is a powerful tool to examine these interactions on an unprecedented scale.
Microarray Analysis: Anti-Human SMAD4 (clone R516.2.1 D12) specificity was evaluated using CDI HuProt ™ Human Proteome Microarray and subsequently analyzed with GenePix Pro Image Acquisition and Analysis Software, the benchmark tool for the acquisition and analysis of microarray images.
He is leading the international effort to create the Human Protein Atlas with the aim of systematically mapping the entire human proteome.
This NCI funding has allowed me to enter into an exciting collaboration with Steve Carr's lab at the Broad Institute in Boston to do a pilot project testing the feasibility of developing targeted mass spectrometry — based assays to all human proteins, starting with about 1 percent of the basic unmodified human proteome.
«We think this approach has the potential to substantially expand the map of the druggable human proteome,» Cravatt said.
Congratulations to Pacific Northwest National Laboratory's Dr. Richard D. Smith, who received the 2009 Human Proteome Organisation (HUPO) Discovery Award for Proteomic Sciences.
Syed P et al. (2016) Autoantibody Profiling of Glioma Serum Samples to Identify Biomarkers Using Human Proteome Arrays Sci Rep2015 Sep 15; 5:13895.
Microarray Analysis: Test antibody specificity was evaulated using CDI HuProt ™ Human Proteome Microarray and subsequently analyzed with GenePix Pro Image Acquisition and Analysis Software, the benchmark tool for the acquisition and analysis of microarray images.
Hu C et al. (2015) Autoantibody Profiling on Human Proteome Microarray for Biomarker Discovery in Cerebrospinal Fluid and Sera of Neuropsychiatric Lupus.
The Human Protein Atlas (HPA) program is a scientific research program with the goal to explore the entire human proteome.
The CDI HuProt human proteome microarray is a powerful tool that permits examination of the specificity of small molecule and drug substrates on an unprecedented scale.
Learn about the intricacies of the subcellular proteome and how it helps us to understand the complex organization of the human proteome
The human proteome contains more than 30,000 distinct proteins that have been identified so far.
In this webinar, three of the researchers involved in this program will provide their insights regarding the lessons learned from this intensive effort to map the human proteome.
Gain a deeper understanding of the classification of the human proteome, including the tissue - specific proteome, the house - keeping proteome, and the druggable proteome
A decade on from the completion of the Human Genome, the Human Protein Atlas, a multinational research project supported by the non-profit Knut and Alice Wallenberg Foundation, recently launched (November 6, 2014) an open source tissue - based interactive map of the human proteome.
Resolving the spatial distribution of the human proteome at a subcellular level greatly increases our understanding of human biology and disease.
Her research is at the interface between bioimaging and proteomics, and aims to define the spatiotemporal organization of the human proteome at a subcellular level in an effort to understand how variations and deviations in localization contribute to cellular function as well as disease.
In this webinar, we will introduce the new Human Cell Atlas, outlining how it is being used to define the spatiotemporal organization of the human proteome at a subcellular level.
Dr. Lundberg is currently the director of the Cell Atlas, part of the Swedish Human Protein Atlas program, and an elected member of the executive committee of the Human Proteome Organization.
Universities had devolved into degree factories; the fabulous pharaonic government and commercial projects, deploying hundreds of scientists and big - ticket equipment to map the human proteome, catalog the zoo of fundamental particles, or develop the next Ritalin or Viagra, had gone the way of the gorilla and the dodo.
BEIJING — Hoping to create an encyclopedia of proteins in the human body, China's Ministry of Science and Technology today kicked off a $ 40 million effort to map the human proteome — the full complement of proteins — of 10 major organs and tissues, including the heart and liver, in healthy and diseased states.
Chinese researchers contributed just 1 % of data to the global Human Genome Project, but Qin hopes China can play a more significant role in the ongoing Human Proteome Project, a global effort that published a draft map of the human proteome online in Nature on 28 May.
Aurelie Tomczak (Pisabarro, TUD)-- «Discovery of novel chemokines in the human proteome with computational structure - based methods» (2011)
The article, Tissue - based map of the human proteome, is one of 340 papers published by researchers in the Human Protein Atlas project, led by Mathias Uhlén at KTH Royal Institute of Technology / SciLifeLab.
These antibodies have been screened for cross-reactivity against thousands of human proteins (~ 75 % of the human proteome).
Microarray Analysis: Test antibody specificity was evaulated using CDI HuProt ™ Human Proteome Microarray (~ 75 % of the human proteome) and subseqently analyzed with GenePix Pro Image Acquisition and Analysis Software, the benchmark tool for the acquisition and analysis of microarray images.
The largest content microarray in the world is now larger with 81 % of the human proteome on a slide, combining state - of - the - art manufacturing, quality assurance and reproducibility.
The Human Protein Atlas project, funded by the Knut and Alice Wallenberg Foundation, has been set up to allow for a systematic exploration of the human proteome using antibody - based proteomics.
Microarray Analysis: Test antibody specificity was evaulated using CDI HuProt ™ Human Proteome Microarray (19,394 human proteins) and subseqently analyzed with GenePix Pro Image Acquisition and Analysis Software, the benchmark tool for the acquisition and analysis of microarray images.
He receives the Forska!Sverige award for his work on mapping the human proteome.
Protein fragments representing 94 % of the human proteome has been printed on two glass slides at SciLifeLab's facility Protein and Peptide Arrays making it the largest array ever printed world wide.
Using the HuProt microarray array, the binding of fluorescently labeled or biotinylated sample proteins to proteins on the HuProt human proteome microarray — the largest collection of human proteins in the world — can be analyzed simultaneously.
At that time researchers had only just begun to understand the 58 tyrosine kinases in the human proteome, of which EGFR is one.
canSAR contains information on the entire human proteome — the protein equivalent of the human genome - as well as linking to information on more than 1,000 cancer cells lines, used by researchers to study the effect of new drugs in the lab.
It comprises a collection of the human proteome represented by 42 000 unique protein fragments from the Human Protein Atlas resource, covering 19 000 protein coding genes.
Now with ~ 81 % of the human proteome.
About 30 percent of the human proteome is intrinsically disordered.
In fact intrinsically disordered proteins (IDPs) comprise nearly 25 % of the human proteome.
The Human Protein Atlas project, funded by the Knut and Alice Wallenberg Foundation, has been set up to allow for a systematic exploration of the human proteome using Antibody - Based Proteomics.
A comprehensive collection of topics relating to the handling, content, use and applications of the HuProt Human Proteome Microarray.
With ~ 81 % of the human proteome on a single slide, ImmuneProfiler represents a more comprehensive and high - throughput alternative to other assay platforms for the development of predictive early diagnostic tests.
The HuProt ™ human proteome microarray v3.1 contains > 20,000 unique, newly resequenced and individually purified human proteins encompassing 16.152 genes (~ 81 % of the human proteome; see figure, right) and 124 unique mouse gene symbols.
Antibody Cross-Reactivity Testing Using the HuProt ™ Human Proteome Microarray Analysis of several commercially available antibodies against nearly 75 % of the human proteome.
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