There's an ongoing debate over how much mice can mirror
human psychiatric diseases, ranging from autism to depression.
«These are strong evidence that cave fish could be a good model for
human psychiatric disease.»
Not exact matches
«There are a lot of naturally occurring dog
diseases — especially
psychiatric diseases — that are very similar to
human diseases,» Hyun Ji Noh, a geneticist at the Broad Institute and the lead author on the study, told Business Insider.
Of the thousands of ancestral variants reintroduced into modern
humans, only 41 have been linked in genetic studies to
diseases, such as skin conditions and neurological and
psychiatric disorders, he said.
The newly discovered vessels, which were also identified in
human samples, could explain the long - standing conundrum of how the immune system manages to contribute to neurological and
psychiatric disease.
The new study — published October 18, 2016 in the journal Molecular Psychiatry — combined genetic analysis of more than 9,000
human psychiatric patients with brain imaging, electrophysiology, and pharmacological experiments in mutant mice to suggest that mutations in the gene DIXDC1 may act as a general risk factor for
psychiatric disease by interfering with the way the brain regulates connections between neurons.
The European Union's $ 1.1 billion
Human Brain Project, for example, aims to understand the brain as a single system, integrating multiple levels of organisation — surely a key step towards preventing or curing
psychiatric diseases.
There is just one snag: Many
psychiatric diseases in
humans may well result from circuitry found only in
humans.
For the last decade, neuroscientists have been using the non-invasive brain - mapping technique functional called magnetic resonance imaging or fMRI to examine activity patterns in
human and animal brains in the resting state in order to figure out how different parts of the brain are connected and to identify the changes that occur in neurological and
psychiatric diseases.
On the negative side, the researchers found that many of the genes whose activity is unique to modern
humans are linked to
diseases like Alzheimer's
disease, autism and schizophrenia, suggesting that these recent changes in our brain may underlie some of the
psychiatric disorders that are so common in
humans today.
«We discovered associations between Neandertal DNA and a wide range of traits in modern
humans, including immunological, dermatological, neurological,
psychiatric, and reproductive
diseases,» said senior author John Capra, assistant professor of biological sciences at Vanderbilt University.
The researchers» strategy — generating
disease - specific nerve cells, identifying a causative gene for developmental defects, validating the gene - specific defect in animal models, and then investigating interactions with other genes both in animal models and in
humans — represents a promising new approach for understanding the mechanisms underlying some of the most intractable
psychiatric illnesses.
psychiatry (adj.
psychiatric) A field of medicine where doctors study and treat
diseases of the
human mind.
Since they confer regulation on the majority of
human genes, it is not surprising that microRNAs are involved in numerous biological processes, including cardiovascular, immunological, neurodegenerative, and
psychiatric diseases and cancer.
Based on their effect on neurons, as well as their locations in the genome, the researchers think that many of the HARs guide genes involved in brain development, as well as
psychiatric diseases that are uniquely
human, such as autism and schizophrenia.
Differentiation from
human pluripotent stem cells of cortical neurons of the superficial layers amenable to
psychiatric disease modeling and high - throughput drug screening.
By reprogramming
human skin cells and other cells from patients with neurologic and
psychiatric diseases into induced pluripotent stem cells (iPSCs) and induced neurons (iN), his work seeks to decipher the progression and mechanisms that lead to brain cell dysfunction.
As of June 2015, there were 116 clinical trials evaluating the possible anti-disease effect of curcumin in
humans, including studies on cancer, gastrointestinal
diseases, cognitive disorders, and
psychiatric conditions.
«If I contributed something to this conversation, I think it is looking beyond [animal - to -
human] infection to some of these really intriguing areas that are hiding in plain site, beyond cancer and beyond heart
disease to a shared overlap in
psychiatric illnesses,» said Natterson - Horowitz, an organizer of the event.