Sentences with phrase «human psychiatric disorders»

Using a nonhuman primate model, their findings provide insight into the mechanisms of human psychiatric disorders associated with emotion dysregulation, such as PTSD (post-traumatic stress disorder) and schizophrenia.

Now, one researcher is studying them for another reason: Their behavior may provide clues to the genetic basis of some human psychiatric disorders.

Not exact matches

Of the thousands of ancestral variants reintroduced into modern humans, only 41 have been linked in genetic studies to diseases, such as skin conditions and neurological and psychiatric disorders, he said.

«Now that we've confirmed the human relevance of our findings, our future goal is to better understand the roles of the different cell types in psychiatric and neurological disorders, and to determine if targeting these cells can actually help treat seizures,» concluded Paz.

The authors suggest that the intricate balance between the signaling of neurons in these three brain regions may be crucial for normal social behavior in humans, and that disruption may contribute to various psychiatric conditions, including autistic spectrum disorders.

An idea that has gained credibility is that these disorders reflect extremes of the normal spectrum of human behaviour, rather than a distinct psychiatric illness.

In the new study, the researchers discovered that during the second trimester of human brain development, oRG cells express genes related to a fundamental signaling pathway called mTOR, defects in which have previously been implicated in autism and several other psychiatric disorders.

The inability to watch living human brain cells in action has hampered scientists in their efforts to understand psychiatric disorders.

On the negative side, the researchers found that many of the genes whose activity is unique to modern humans are linked to diseases like Alzheimer's disease, autism and schizophrenia, suggesting that these recent changes in our brain may underlie some of the psychiatric disorders that are so common in humans today.

These findings could have implications for understanding the genetic basis of methamphetamine addiction in humans and the development of novel therapeutics for prevention and treatment of substance abuse and possibly other psychiatric disorders.

The limited genetic diversity of dog breeds facilitates identification of genes, functional variants and regulatory pathways underlying complex psychiatric disorders that are mechanistically similar in dogs and humans.

We are especially interested in understanding how signaling is regulated in identified neuronal circuits that are important for these human neurological and psychiatric disorders.

Cognition and behaviour / Animal cognition and behaviour; Neurological and psychiatric conditions / Developmental disorders; Neurological and psychiatric conditions / Psychiatric disorders; Cognition and behaviour / human cognition and behaviour

As of June 2015, there were 116 clinical trials evaluating the possible anti-disease effect of curcumin in humans, including studies on cancer, gastrointestinal diseases, cognitive disorders, and psychiatric conditions.

John Medina is a developmental molecular biologist with special research interests in the isolation and characterization of genes involved in human brain development and the genetics of psychiatric disorders.

It advocates for those with psychiatric disorders and is fighting for equality, human rights, and social justice.

As they age, they may become suicidal, addicted to alcohol or other drugs, enmeshed in violent relationships, and unable to care for their children.64, 76 Delinquent females also engage in sexual activity at an earlier age than nonoffenders, placing them at greater risk for unwanted pregnancy and human immunodeficiency virus.78 Understanding psychiatric morbidity and associated risk factors among delinquent females could help us to improve treatment and reduce the cycle of disorder and dysfunction.

The importance of considering GxE interactions in understanding the aetiology of complex psychiatric disorders has become more widely acknowledged (Caspi & Moffitt 2006; Canli & Lesch 2007; Munafo et al. 2009), yet the association between specific cultural and genetic factors underlying affective disorders across human populations has been largely unexplored until now.

[3] That is, estimates of shared environmental effects (c 2 -LCB- \ displaystyle c ^ -LCB- 2 -RCB--RCB--RRB- in human studies are small, negligible, or zero for the vast majority of behavioural traits and psychiatric disorders, whereas estimates of non-shared environmental effects (e 2 -LCB- \ displaystyle e ^ -LCB- 2 -RCB--RCB--RRB- are moderate to large.