Sentences with phrase «human receptors»
Finally, the GLIC system was exploited to solve the structure of human receptors through the generation of functional chimeras.
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Cat taste receptors respond in a unique way to bitter compounds compared with human receptors, according to research published in the open access journal BMC Neuroscience.
«Identification of the H5N1 viruses with the ability to recognize human receptors would bring us one step closer to a pandemic strain,» Kawaoka says.
In their work, Cohen and Brady engineered gut bacteria to produce specific ligands, N - acyl amides, that bind with a specific human receptor, GPR 119, that is known to be involved in the regulation of glucose and appetite, and has previously been a therapeutic target for the treatment of diabetes and obesity.
They characterized the set of HA mutations required to increase the preference of the viruses for human receptors, discovering that only a single amino acid change in the HA sequence is necessary for this to occur.
She is interested in understanding how malaria parasites interact with the human host, and is currently working on identifying novel extracellular interactions between Plasmodium falciparum surface proteins and human receptor proteins.
Tsibane T, Ekiert DC, Krause JC, Martinez O, Crowe JE, Wilson IA, Basler CF. Influenza human monoclonal antibody 1F1 interacts with three major antigenic sites and residues mediating human receptor specificity in H1N1 viruses.
«Recognition of human receptors can serve as molecular markers for the pandemic potential of the [isolated strains].»
Unlike the human receptors, which respond to odour molecules, the snakes» thermal receptors respond directly to heat, triggering nerve impulses that their brain interprets as an image.
H5N1 can bind to human receptors, for example, but H5N1 proved receptor specificity is not enough to be highly transmissible.
Several forms with mutations in three amino acids bound far more strongly to human receptors; they had switched specificity from bird to human.
The cat receptor was less sensitive to aloin and more sensitive to denatonium than the human receptor.
But the new protein structure suggests that the 1918 strain, despite its avianlike sequence, had a shape that helped it bind tightly to the human receptor and infect cells, Skehel says — which helps explain why the 1918 strain spread so well in the human population.
«Luckily, H7N9 viruses just don't yet seem well adapted for binding to human receptors,» said Ian A. Wilson, the Hansen Professor of Structural Biology and chair of the Department of Integrative Structural and Computational Biology at TSRI.
«Because publications to date have implied that H7N9 has adapted to human receptors, we felt we should make a clear statement about this,» said James C. Paulson, chair of TSRI's Department of Cell and Molecular Biology.
The human receptors were biologically functional in the mice, but the real question was whether the mice could use the new visual information.