To overcome these hurdles, Bhatia and her team reprogrammed
human skin cells into induced pluripotent stem cells (iPSCs)-- embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease.
Sheng Ding, PhD, has discovered how to turn
human skin cells into insulin - producing pancreatic cells.
Scientists at the Gladstone Institutes have successfully converted
human skin cells into fully - functional pancreatic cells.
LA JOLLA — For the first time, scientists have turned
human skin cells into transplantable white blood cells, soldiers of the immune system that fight infections and invaders.
Two studies demonstrate the first direct, chemical reprogramming of mouse and
human skin cells into heart muscle and neural cells.
In the Science study, led by first author Nan Cao, PhD, a postdoctoral fellow in Ding's lab, the researchers used a cocktail of nine chemicals to change
human skin cells into beating heart cells.
They were created by injecting DNA derived from
human skin cells into eggs taken from cows ovaries which have had virtually all their genetic material removed.
Two teams of scientists have independently discovered a way to turn ordinary
human skin cells into stem cells with the same characteristics as those derived from human embryos, a breakthrough that could open the door for advanced medical therapies.
That's an impressive claim, and it's based on newly released data from his lab that shows the ability to turn
human skin cells into liver cells.
«Scientists Turn
Human Skin Cells Into Insulin - producing Cells.»
We are improving how we reprogram
human skin cells into heart cells, and are investigating the most rapidly evolving areas of the human genome to better understand human disease and evolution.
The advantages of this approach began to emerge in 2011, when Dr. Ding announced that he had used his «chemical reprogramming» method to convert
human skin cells into brain cells.
In 2007, scientists demonstrated that they could transform
human skin cells into iPS cells, bypassing the destruction of embryos.
SAN FRANCISCO, CA — Scientists at the Gladstone Institutes and the University of California, San Francisco (UCSF) have successfully converted
human skin cells into fully - functional pancreatic cells.
Past work by Yoo and his colleagues — then at Stanford University — showed that exposure to two short snippets of RNA turned
human skin cells into neurons.
The ability of scientists to convert
human skin cells into other cell types, such as neurons, has the potential to enhance understanding of disease and lead to finding new ways to heal damaged tissues and organs, a field called regenerative medicine.
Writing in the latest issue of the journal Nature, researchers in the laboratories of Gladstone Senior Investigator Sheng Ding, PhD, and UCSF Associate Professor Holger Willenbring, MD, PhD, reveal a new cellular reprogramming method that transforms
human skin cells into liver cells that are virtually indistinguishable from the cells that make up native liver tissue.
A new cellular reprogramming method has been revealed that transforms
human skin cells into liver cells that are virtually indistinguishable from the cells that make up native liver tissue.
«Pain and itch in a dish: Scientists convert
human skin cells into sensory neurons.»
Wells's team first turned
human skin cells into pluripotent stem cells, which can grow into any type of tissue.
Two teams independently discover a way to turn ordinary
human skins cells into stem cells with the same characteristics as those derived from human embryos, a breakthrough that could open the door for advanced medical therapies.
Not exact matches
To make the HSCs, the Harvard group used
human skin cells to create induced pluripotent stem
cells (iPSCs), adult
cells researchers genetically reprogram to an embryonic - stem -
cell state, where they can grow
into any kind of
cell.
Using viral gene insertion and regulatory proteins, researchers turned adult
human skin cells directly
into adult
human blood
cells, without first returning them to a fully pluripotent state.
Anand and his colleague Susan McKay started with
human skin cells, which they turned
into induced pluripotent stem
cells (iPSCs) using a tried - and - tested method.
To do this, the researchers coaxed three fluorescent molecules
into the mitochondria of living
human skin cells.
«We have converted
skin cells to stem
cells and developed a highly efficient process to convert these stem
cells into kidney structures that resemble those found in a normal
human kidney.
Scientists recently announced that they have found a way to turn
human skin into cells that have all the therapeutic potential of embryonic stem
cells.
By reprogramming
skin cells into nerve
cells, researchers at Karolinska Institutet are creating
cell models of the
human brain.
«You'd still have to ration the therapy,» cautions Robert Hariri, chief researcher at Anthrogenesis in Cedar Knolls, New Jersey, which announced this year that it had morphed
human placental stem
cells into nerve, blood, cartilage,
skin, and muscle
cells.
«We culture typical
skin cell of the epidermis, such as
human keratinocytes, in our dishes to form an artificial epidermis with all of its natural layers,» explained Sibylle Thude, the biologist who led the investigation
into the accreditation.
Last month, Shinya Yamanaka at Kyoto University showed he could transform adult
skin cells into cells akin to
human embryonic stem
cells.
Similarly, the three research teams that last week reported turning mouse
skin cells into embryolike
cells say they will have to study embryonic
cells to learn how to reprogram
human cells in the same way and to understand their potential.
One uses primary hepatocytes obtained from livers donated for transplant; the second uses stem
cells derived from
human skin samples and guided
into hepatocyte - like
cells, Bhatia says.
The swirling dislodged particles travel upward with the
human convection plume, or currents of warmed air that rise around any
human body, then get swept
into a filter that takes out contaminants like dust, lint, and
skin cells.
For the new study, the team used a
cell - reprogramming technique (similar to those used to reprogram
skin cells into stem
cells) to generate
human DRG - type sensory neurons from ordinary
skin cells called fibroblasts.
It is possible to force
human skin cells to turn back
into embryonic stem
cells in the lab, but this doesn't seem to be something we are able to achieve without intervention.
In an advance that could solve many of the ethical and technical issues involved in stem
cell research, two groups of scientists have independently converted
human skin cells directly
into stem
cells without creating or destroying embryos.
When they added cytokines IL - 4 and IL - 13 to cultured
human skin cells, the allergic immune response kicked
into high gear and lipids became shorter.
Another team, from Stanford University, converted
human skin cells directly
into neurons without first stopping at the stem
cell stage, potentially making the process more efficient.
The
skin was changed directly
into what appears to be functional adult
human blood
cells.
«We used
human skin cells that we obtained from patients affected with ALS and converted them
into neurons via a technology called induced pluripotent stem
cell production,» she explains.
Using a process called cellular reprogramming, the researchers take a patient's
skin cells, convert them
into so - called induced pluripotent stem (iPS)
cells, which can differentiate
into all the
cells within the
human body.
«
Human skin cells transformed directly
into motor neurons.»
Scientists have discovered a new way to convert
human skin cells directly
into motor neurons (above).
Scientists at the University of Luxembourg have succeeded in turning
human stem
cells derived from
skin samples
into tiny, 3 - D, brain - like cultures that behave very similarly to
cells in the
human midbrain.
Both teams successfully used these to reprogramme
skin cells in a lab dish
into cells resembling embryonic stem
cells, which have the ability to turn
into any tissue of the
human body.
The epithelial stem
cells, when implanted
into immunocompromised mice, regenerated the different
cell types of
human skin and hair follicles, and even produced structurally recognizable hair shaft, raising the possibility that they may eventually enable hair regeneration in people.
Human - associated bacteria disperse into and throughout the built environment by three primary mechanisms: (1) direct human contact with indoor surfaces; (2) bioaerosol particle emission from our breath, clothes, skin and hair; and (3) resuspension of indoor dust containing previously shed human skin cells, hair and other bacteria - laden parti
Human - associated bacteria disperse
into and throughout the built environment by three primary mechanisms: (1) direct
human contact with indoor surfaces; (2) bioaerosol particle emission from our breath, clothes, skin and hair; and (3) resuspension of indoor dust containing previously shed human skin cells, hair and other bacteria - laden parti
human contact with indoor surfaces; (2) bioaerosol particle emission from our breath, clothes,
skin and hair; and (3) resuspension of indoor dust containing previously shed
human skin cells, hair and other bacteria - laden parti
human skin cells, hair and other bacteria - laden particles.
Human embryonic stem
cells derived from affected embryos during a pre-implantation diagnostic (PGD), as well as the conversion of somatic
cells, such as
skin fibroblasts,
into induced pluripotent stem
cells by genetic manipulation, offer the unique opportunity to have access to a large spectrum of disease - specific
cell models.
The near - infrared light that causes the nanotubes to fluoresce can penetrate about eight centimeters
into human tissue, so physicians could potentially shine the light through
skin and flesh to look for fluorescence from nanotubes signaling the presence of cancer
cells.