Researchers at the Fund for the Replacement of Animals in Medical Experiments (FRAME) in Nottingham, have just finished the first stage of development, which draws on research showing that
human skin cells produce chemicals called cytokines when exposed to chemicals that are irritants.
Not exact matches
In May 2013, Mitalipov was the first scientist in the world to demonstrate the successful use of somatic
cell nuclear transfer, or SCNT, to
produce human embryonic stem
cells from an individual's
skin cell.
In the study,
human melanocytes — the
cells that
produce the
skin pigment melanin — were exposed to estrogen levels usually seen during pregnancy.
The health of the
human vagina depends on a symbiotic / mutually beneficial relationship with «good» bacteria that live on its surface feeding on products
produced by vaginal
skin cells.
In their paper, publishing today in Biofabrication, the team show how they utilise 3D bioprinting to control the distribution of melanin -
producing skin cells (melanocytes) on a biomimetic tissue substrate, to
produce human - like
skin pigmentation.
Indeed, when the researchers engineered connective tissue
cells from mouse and
human skin to
produce PRDM16 and C / EBP - beta, they became fully functional brown fat.
One team in Japan, and another in the US, have independently shown it is possible to
produce embryonic - like stem
cells directly from a patient's own
skin cells without having to create and destroy a cloned
human embryo first.
The epithelial stem
cells, when implanted into immunocompromised mice, regenerated the different
cell types of
human skin and hair follicles, and even
produced structurally recognizable hair shaft, raising the possibility that they may eventually enable hair regeneration in people.
Humans have many
cell types - nerve
cells, blood
cells,
skin cells, to name a few - and while each
cell contains the same genetic instructions, different parts of the genetic information are used to
produce proteins in each type of
cell.
A strain of bacteria that commonly lives on the
human skin produces 6 - HAP that can kill cancer
cells without harming other
cells.
These
cells, first described in
humans in November 2007, are
produced by inserting certain stem -
cell - associated genes into regular adult
cells (like
skin cells).
Gladstone scientist Dr. Sheng Ding has exposed more chameleon - like qualities of the
human skin cell, using chemical cocktails to turn
skin cells into fully functional brain, heart, liver, and insulin -
producing pancreas
cells.
Researchers at the University of North Carolina at Chapel Hill School of Medicine have transformed
cells from
human skin into
cells that
produce insulin, the hormone used to treat diabetes.
Yamanaka's group used
human adult
skin cells and induced them to become iPS
cells by having them
produce the same protein factors that the mouse iPS
cells had.
«Scientists Turn
Human Skin Cells Into Insulin -
producing Cells.»
Human skin cells have also been directly converted into neurons that can be used to study and find treatments for diseases in the brain, as well as liver
cells and insulin -
producing cells of the pancreas.
Sheng Ding, PhD, has discovered how to turn
human skin cells into insulin -
producing pancreatic
cells.
Only a year after he
produced the first iPS
cells from adult mouse
skin cells, Yamanaka generated iPS
cells from adult
human skin cells, employing
human versions of the same four genes that he had used in the mouse work.
Human Growth Hormone: Produced in the anterior pituitary and regulated from hypothalamus by growth hormone releasing hormone and growth hormone inhibiting hormone (aka somatostatin), human growth hormone (hGH, aka somatotrophin) enters the circulation and is delivered to the liver where it is converted to growth factors that initiate muscle, bone, and cartilage production; improve kidney function, skin elasticity, and cell repair and regenera
Human Growth Hormone:
Produced in the anterior pituitary and regulated from hypothalamus by growth hormone releasing hormone and growth hormone inhibiting hormone (aka somatostatin),
human growth hormone (hGH, aka somatotrophin) enters the circulation and is delivered to the liver where it is converted to growth factors that initiate muscle, bone, and cartilage production; improve kidney function, skin elasticity, and cell repair and regenera
human growth hormone (hGH, aka somatotrophin) enters the circulation and is delivered to the liver where it is converted to growth factors that initiate muscle, bone, and cartilage production; improve kidney function,
skin elasticity, and
cell repair and regeneration.
The
human skin produces approximately one million
skin cells every 40 minutes.