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Human skin pigmentation recreated — with a 3 - D bioprinter.»
«This is the same trend we see on an intra-species level for
human skin pigmentation around the globe.»
Not exact matches
For example, since
skin color has no demonstrable relation to intellectual ability, esthetic sensitivity, or character, it follows that no significant conclusions about a person's characteristically
human behavior can be drawn from the nature of his
pigmentation.
The combined data allowed the team to find eight sites in the
human genome that are particularly associated with the level of
skin pigmentation.
Changes to
skin pigmentation pathways probably reflect selective pressures related to sunlight exposure that
humans experienced as they spread out from humanity's origins in Africa to other parts of the world and adapted to local environments.
Variation in
pigmentation among
human populations may reflect local adaptation to regional light environments, because dark
skin is more photoprotective, whereas pale
skin aids the production of vitamin D. Although genes associated with
skin pigmentation have been identified in European populations, little is known about the genetic basis of
skin pigmentation in Africans.
Despite the wide range of
skin pigmentation in
humans, little is known about its genetic basis in global populations.
The discovery sheds new light on our understanding of the genetic complexity underpinning variations in
human pigmentation, and could advance our knowledge of conditions linked to
pigmentation, such as
skin, testicular, prostate and ovarian cancers.
Analysis of the genetics of
skin pigmentation in Africans informs upon melanocyte biology and the evolution of
skin pigmentation in
humans.
This study sheds light on the evolutionary history, and adaptive significance, of
skin pigmentation in
humans.
«We've been trying to track down the genetic and molecular basis of naturally occurring traits — such as hair and
skin pigmentation — in fish and
humans to get insight into the general principles by which traits evolve,» said David Kingsley, PhD, professor of developmental biology.
We show that both dark and light
pigmentation alleles arose before the origin of modern
humans and that both light and dark pigmented
skin has continued to evolve throughout hominid history.
iSAFE identified identical mutations in multiple non-African populations in 5 regions associated with
skin pigmentation, suggesting an early response to the onset of selection as
humans migrated out of Africa.
«Our aim with this project was to use this method to demonstrate the feasibility of making 3D in - vitro pigmented
human skin constructs, with uniform
skin pigmentation.»
A new method for controlling
pigmentation in fabricated
human skin has been developed by researchers from A * STAR's Singapore Institute of Manufacturing Technology (SIMTech) and the Singapore Centre for 3D Printing (SC3DP) at Nanyang Technological University.
In their paper, publishing today in Biofabrication, the team show how they utilise 3D bioprinting to control the distribution of melanin - producing
skin cells (melanocytes) on a biomimetic tissue substrate, to produce
human - like
skin pigmentation.
Those markers can tell the story of
human adaptation as early man moved from equatorial Africa into lower - light regions, and may explain changes in
skin pigmentation to metabolize more sunlight, or how indoor living has silently damaged
human health.
Scientists at deCODE genetics and colleagues in Iceland and Holland today report the discovery of variations in the
human genome that influence
pigmentation of hair, eyes and
skin.
Approximately 15 genes have been directly associated with
skin pigmentation variation in
humans, leading to its characterization as a relatively simple trait.
By considering diverse, under - studied African populations, we show how the architecture of
skin pigmentation can vary across
humans subject to different local evolutionary pressures.
Indeed, a likely reason that melanin
pigmentation devolved was to permit
humans who migrated north and south of the equator to make enough vitamin D in their
skin to satisfy their requirement (96).
Albino dogs as well as
humans are predisposed to a variety of
skin problems due to total lack of
skin pigmentation.