The reprogramming of
human somatic cells into induced pluripotent stem cells (iPSCs) offers tremendous potential for cell therapy, basic research, disease modeling, and drug development.
Not exact matches
In
humans,
somatic cells — the generic
cells that grow
into muscle, bone, and organs — start off unisex.
Opponents said that the measure should have banned
somatic cell nuclear transfer; it criminalized only the «implantation» of an embryo
into a woman to create a
human clone.
But the favored reprogramming technique,
somatic cell nuclear transfer (SCNT), otherwise known as research cloning, is fraught with ethical pitfalls as well as technical difficulties because it entails creating a
human embryo by inserting an adult
cell nucleus
into an ooctye.
To sum up, we have seen that
somatic cells of various origins, including
human, can be lineage reprogrammed
into induced neurons.
Human embryonic stem
cells derived from affected embryos during a pre-implantation diagnostic (PGD), as well as the conversion of
somatic cells, such as skin fibroblasts,
into induced pluripotent stem
cells by genetic manipulation, offer the unique opportunity to have access to a large spectrum of disease - specific
cell models.
WIKIMEDIA, CSIROAfter
human somatic cells are reprogrammed
into induced pluripotent stem
cells (iPSCs), the resulting
cells retain both genetic and epigenetic indicators of the age of the person who donated the
somatic -
cell progenitors, scientists have found.
The advent of
human induced pluripotent stem
cells has been heralded as a major breakthrough in the study of pluripotent stem
cells, for these
cells have yielded fundamental insights
into the reprogrammability of
somatic cell fates, but also because of their seemingly great promise in applications, including potential uses in
cell therapy.
Human pluripotent stem cells derived from embryos (human Embryonic Stem Cells or hESCs) or generated by direct reprogramming of somatic cells (human Induced Pluripotent Stem Cells or hiPSCs) can proliferate almost indefinitely in vitro while maintaining the capacity to differentiate into a broad diversity of cell t
Human pluripotent stem
cells derived from embryos (human Embryonic Stem Cells or hESCs) or generated by direct reprogramming of somatic cells (human Induced Pluripotent Stem Cells or hiPSCs) can proliferate almost indefinitely in vitro while maintaining the capacity to differentiate into a broad diversity of cell t
cells derived from embryos (
human Embryonic Stem Cells or hESCs) or generated by direct reprogramming of somatic cells (human Induced Pluripotent Stem Cells or hiPSCs) can proliferate almost indefinitely in vitro while maintaining the capacity to differentiate into a broad diversity of cell t
human Embryonic Stem
Cells or hESCs) or generated by direct reprogramming of somatic cells (human Induced Pluripotent Stem Cells or hiPSCs) can proliferate almost indefinitely in vitro while maintaining the capacity to differentiate into a broad diversity of cell t
Cells or hESCs) or generated by direct reprogramming of
somatic cells (human Induced Pluripotent Stem Cells or hiPSCs) can proliferate almost indefinitely in vitro while maintaining the capacity to differentiate into a broad diversity of cell t
cells (
human Induced Pluripotent Stem Cells or hiPSCs) can proliferate almost indefinitely in vitro while maintaining the capacity to differentiate into a broad diversity of cell t
human Induced Pluripotent Stem
Cells or hiPSCs) can proliferate almost indefinitely in vitro while maintaining the capacity to differentiate into a broad diversity of cell t
Cells or hiPSCs) can proliferate almost indefinitely in vitro while maintaining the capacity to differentiate
into a broad diversity of
cell types.