We suggest correct identification of the origin of these cells (using
human specific markers, which define cell membranes) is essential in order to distinguish viable donor cells from host inflammatory cells which have engulfed transplanted cells.
(E) Rhodopsin - positive material (red) is present within the cell membrane of
human specific marker (HSM)- labelled iPS - RPE (green) 8 days post-transplantation and in the tips of the host outer segment (OS) layer.
Not exact matches
Milestones are important
markers of normal
human development and they are often achieved within a
specific age range.
One of their goals at the conference was to pinpoint
specific markers of these expressions, and then use them to identify the emergence of
humans within the paleoanthropological record.
The results showed that, when applied, a long - term inhibition of Rho - kinase signaling increased the expressions of chondrocyte -
specific genes and differentiation
markers in
human chondrosarcoma 2/8 cells.
The use of cell surface
markers to isolate
specific cell populations is one common method for separating cells; however, isolating live cells based on their RNA expression is a powerful new way enabling the study of small cell niches in nongenetically modified animal models and
human tissue.
Researchers at Karolinska Institutet have identified cell surface
markers specific for the very earliest stem cells in the
human embryo.
Expanding from their previous studies with mice, the researchers first established that under
specific conditions, culturing
human embryonic stem cells with fibroblast growth factor 2 (FGF2) leads to neural differentiation particular to the midbrain / hindbrain region — the location of the cerebellum — within three weeks, and the expression of
markers for the cerebellar plate neuroepithelium — the part of the developing nervous system
specific for the cerebellum — within five.
This molecular slingshot could «shoot» and deliver drugs at precise locations in the
human body once triggered by
specific disease
markers.
Asialoglycoprotein receptor 1 is a
specific cell - surface
marker for isolating hepatocytes derived from
human pluripotent stem cells.
Cells were stained with antibodies
specific for
human cell surface
markers: CD326 / ESA - FITC, CD24 - PE, and CD44 - PE - Cy7 (BD Pharmingen, San Jose, CA, USA).
(A) Retinal section obtained from a P150 eye immunostained with
human -
specific nuclear
marker.
We can envision that DAXX can serve as a precise prognostic
marker in PCa and that tissue -
specific shRNA delivery targeted against DAXX can be employed in the treatment of metastatic prostate cancer in patients, in particular if we discover, through additional studies, that DAXX is a
marker for lethal PCa in
humans.
The antibodies listed above in the immunocytochemistry section were also used on eye sections together with a cocktail of antibodies generated against
human -
specific markers (HSM) to identify
human cells (the Oka blood group antigen, mouse TRA -1-85, 1 ∶ 10 (a kind gift from Peter Andrews, University of Sheffield, Sheffield, UK) together with mouse
human nuclear antigen, 1 ∶ 1000, Millipore).
The success of
marker - based approaches for dissecting haematopoiesis in mouse and
human is reliant on the presence of well - defined cell surface
markers specific for diverse progenitor populations.
Germ cell
specific markers are also expressed in embryoid bodies derived from
human ES suggesting the presence of PGC's, so I am developing methods to enhance their formation and isolation.
Drs. Nordone and Birkenheuer are investigating a newly discovered molecule (TREM - 1) that is a
specific marker of sepsis in mice and
humans to determine whether it could indicate sepsis in dogs.
Sauer, E. P., J. L. VandeWalle, M. J. Bootsma, and S. L. McLellan, 2011: Detection of the
human specific Bacteroides genetic
marker provides evidence of widespread sewage contamination of stormwater in the urban environment.
Detection of the
human specific Bacteroides genetic
marker provides evidence of widespread sewage contamination of stormwater in the urban environment
Performed FACS for characterizing MSC by using
markers specific for
human, pigs and rats respectively.