New research from scientists at Huntsman Cancer Institute (HCI) at the University of Utah and collaborators at University of Utah Health (U of U Health) sheds light on the complex process that occurs in the development of
human sperm stem cells.
Using single cell RNA sequencing analysis, the Cairns lab profiled cells individually, establishing the gene expression profile in
human sperm stem cells.
Not exact matches
Newcastle University and the NorthEast England
Stem Cell Institute are aware that the research paper «Derivation of
Human Sperm from Embryonic
Stem Cells» by a group led by Professor Karim Nayernia has been withdrawn from the academic journal
Stem Cells and Development.
In June Italian scientists announced the first
human embryonic
stem cells derived from parthenotes — embryo - like structures formed when an egg starts to divide on its own, with no
sperm involved.
They prohibit breeding animals in which
human stem cells might have become
sperm or eggs, and they rule out primate -
human experiments.
Ralph Brinster, part of the team at the University of Pennsylvania in Philadelphia that first cultured
sperm stem cells in the lab, has written that culturing
stem cells from
human sperm is not far off —
humans and mice, like other mammals, he says, require similar growth factors.
The germ cells made from
stem cells stopped differentiating in the mice before they produced mature
sperm (likely because of the significant differences between the reproductive processes of
humans and mice) regardless of the fertility status of the men from whom they were derived.
In 2009, Reijo Pera showed that it is possible to generate functional,
sperm - producing germ cells from
human embryonic
stem cells grown under certain conditions in the laboratory.
Scientists have shown how the precursors of egg and
sperm cells — the cells that are key to the preservation of a species — arise in the early embryo by studying pig embryos alongside
human stem cells.
Dr Harris normally took a libertarian stand on bioethical issues and was a forceful and reliable supporter of
human embryonic
stem cell research, abortion, euthanasia, anonymous
sperm donation, IVF for lesbians and single parents and so on.
Human sperm created from
stem cells.