Sentences with phrase «human stem cells as»

The self - renewable capacity of these cells, their ability to differentiate into several tissue progenitors (neural, mesenchymal stem cells...), and the possibility to work with mutated cell lines define human stem cells as a good basis for screening compounds libraries in order to discover new potential drugs for monogenic diseases.

This is exciting because we can begin to draft a roadmap charting the molecular routes that are available to human stem cells as they navigate their way between the two states.»

Not exact matches

Benedict argued that non-conjugal reproduction such as in vitro fertilization had created «new problems» ¯ the freezing of human embryos, for instance, and the selective abortion of medically implanted embryos, together with pre-implantation diagnosis, embryonic stem - cell research, and attempts at human cloning.

The difficulties associated with obtaining nerve tissue at the correct stage of development and differentiation from aborted embryos means that foetal tissue transplantation is no longer in favour, but the creation of human embryos specifically as sources of stem cells, and the push to use «spare» embryos from IVF treatments is gatheringmomentum.

research; since most of the reports have concentrated on justifying the creation of cloned human embryos for research into and treatment of neurodegenerative diseases such as Parkinson's, «stem - cells» has become synonymous with «embryonic stem - cells» in the public imagination.

Proponents of human cloning assert that this is the only method of producing pluripotent stem cells with the same genetic make - up as adult patients.

Human cloning has been proposed as a means of generating human embryos that can be destroyed to obtain embryonic stem cHuman cloning has been proposed as a means of generating human embryos that can be destroyed to obtain embryonic stem chuman embryos that can be destroyed to obtain embryonic stem cells.

As we read this history, the furor over stem cells was fueled by numerous factors: the near - universal human desire for magic; patients» desperation in the face of illness and their hope for cures; the belief that biology can now do anything; the reluctance of scientists to accept any limits (particularly moral limits) on their research; the impact of big money from biotech stocks, patents, and federal funding; the willingness of America's elite class to use every means possible to discredit religion in general; and the need to protect the unlimited abortion license by accepting no protections of unborn human life.

Whilst acknowledging that many questions remain unanswered in the debate between those who would advocate the use of stem cells taken from human embryos, and those experimenting on stem cells drawn from tissues of the adult human body, there is a lengthy discussion of the moral status of the human embryo as being a crucial matter in this regard.

Stem cells have also been identified in human milk, and have the potential to differentiate into mammary epithelial lineages under mammary differentiation conditions in vitro, as well as other cell types in corresponding microenvironments, including bone cells, brain cells, liver cells, pancreatic beta cells and heart cells.

As well as allowing the use of stem cells grown from established cell lines, the technology could enable the creation of improved human tissue models for drug testing and potentially even purpose - built replacement organAs well as allowing the use of stem cells grown from established cell lines, the technology could enable the creation of improved human tissue models for drug testing and potentially even purpose - built replacement organas allowing the use of stem cells grown from established cell lines, the technology could enable the creation of improved human tissue models for drug testing and potentially even purpose - built replacement organs.

Former Senator Rick Santorum (R — PA) is a strong backer of adult stem - cell research, and opposed to embryonic stem - cell research because he views destruction of embryos as destruction of human life.

Since the first human brain organoids were created from stem cells in 2013, scientists have gotten them to form structures like those in the brains of fetuses, to sprout dozens of different kinds of brain cells, and to develop abnormalities like those causing neurological diseases such as Timothy syndrome.

On Thursday, the United Nations» member states will consider two resolutions: One resolution would ban all human cloning methods, including efforts to use cloned embryonic stem cells to try and generate healthy tissues, or to treat degenerative diseases such as Parkinson's.

The ability of SIF - seq to use reporter assays in mouse embryonic stem cells to identify human embryonic stem cell enhancers that are not present in the mouse genome opens the door to intriguing research possibilities as Dickel explains.

Human embryonic stem cells are at last being tested in common, potentially fatal diseases such as heart failure and diabetes

Decades after they were discovered, human embryonic stem cells are being trialled as a treatment for two major diseases: heart failure and type 1 diabetes

Induced pluripotent stem cells (known as iPSCs) are similar to human embryonic stem cells in that both cell types have the unique ability to self - renew and have the flexibility to become any cell in the human body.

When Gupta's team added salinomycin to cultured human breast - cancer cells, it was about 100 times as effective at killing the cancer stem cells as popular anti-cancer drug, paclitaxel.

A team of researchers at the Stanford University School of Medicine has used a gene - editing tool known as CRISPR to repair the gene that causes sickle cell disease in human stem cells, which they say is a key step toward developing a gene therapy for the disorder.

Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human cell types, including normal and cancerous colon, lung and liver cells, as well as brain, skin, blood and embryonic stem cells.

Several studies have supported a role for cancer stem cells in the aggressive brain tumors called glioblastoma, but those studies involved inducing human tumors to grow in mice, and as such their relevance to cancer in humans has been questioned.

«These results provide the basis for the potential implementation of 5 - LO - inhibitors as stem cell therapeutic agents for a sustained AML cure, although this must be investigated further in preclinical and clinical studies in humans,» explains Dr. Ruthardt.

The newly discovered human cells, named «cord - blood - derived embryonic - like stem cells» or CBEs, are not quite as primitive as embryonic stem cells, which can give rise to any tissue type of the body.

Scientists headed by Dr. Stevens Rehen differentiated human induced pluripotent stem (iPS) cells into neural stem cells and into further complex tridimensional structures, known as neurospheres and brain organoids.

After an earlier stint as a senior writer at Science, where she was widely known for her coverage of the Human Genome Project, Leslie returned as a deputy news editor in 2000, specializing in public health, infectious diseases, stem cells, and ecology.

The researchers reprogrammed the cells to create induced pluripotent stem cells in an FDA - compliant facility at the Broad Stem Cell Research Center; the use of this facility is an important step in the process as preclinical research moves toward human clinical tristem cells in an FDA - compliant facility at the Broad Stem Cell Research Center; the use of this facility is an important step in the process as preclinical research moves toward human clinical triStem Cell Research Center; the use of this facility is an important step in the process as preclinical research moves toward human clinical trials.

A person with spinal injuries today went down in history as the first to receive a treatment derived from human embryonic stem cells (hESCs).

More recently, researchers have induced stem cells from diseased human somatic cells, which may serve as new model systems for various illnesses.

Exosomes had not previously been studied as a way to induce human stem cell differentiation.

The study was supported by a Science of Human Appearance Career Development Award from the Dermatology Foundation and by grants from the Medical Research Council of the UK, the Empire State Development's Division of Science, Technology and Innovation (NYSTAR), New York Stem Cell Science (NYSTEM), and the Biotechnology and Biological Sciences Research Council in the UK (BBSRC), as well as earlier support from the Steven and Michele Kirsch Foundation.

Scientists, with practice, have now been able to make nuclear transfer nearly routine to produce cattle, cats, mice, sheep, goats, pigs, and — as a Korean team announced in May — even human embryonic stem (ES) cells.

«There are still many questions left to answer but we now know that oxygen poor environments, like those often found in advanced human breast cancers serve as nurseries for the birth of cancer stem cells,» says Gregg Semenza, M.D., Ph.D., the C. Michael Armstrong Professor of Medicine and a member of the Johns Hopkins Kimmel Cancer Center.

When the researchers injected human umbilical stem cells behind the retinas of these rats, the Müller glia remained healthy, as did the neural synapses.

In this way they act like embryonic stem cells and share their revolutionary therapeutic potential — and as such, they could eliminate the need for using and then destroying human embryos.

As Nature detailed last week, one Italian science agency recently sent out a call for stem cell grant proposals but specifically excluded human ES cell research, leading three Italian scientists to sue the government.

The vlincRNAs were shown to be present in cancerous cells as well as stem cells and normal human tissues.

The study, «VlincRNAs controlled by retroviral elements are a hallmark of pluripotency and cancer» found that novel non-coding parts of the human genome known as vlincRNAs (very long intergenic, non-coding RNAs) triggered by ancient viruses, participate in the biology of stem cells, and in the development of cancer.

«Having identified this important protein molecule in fruit flies, we can test whether the human version of the protein is important for stem cells and their daughters as well,» said Montell.

In an advance touted as a way around current political logjams, scientists have said they can derive human embryonic stem (ES) cell lines without destroying an embryo.

TOKYO — Research involving human embryonic stem (ES) cells will become easier in Japan as a result of new ethical review requirements that take effect today.

In lab experiments, the researchers isolated exosomes from specialized human cardiac stem cells and found that exosomes alone had the same beneficial effects as stem cells.

Human lungs, like all organs, begin their existence as clumps of undifferentiated stem cells.

Lamberth granted a preliminary injunction on this research after hearing a petition from a group of advocates who argued that, contrary to the U.S. government's view, research on embryonic stem cells does in fact destroy embryos — action that is prohibited by legislation known as the «Dickey - Wicker Amendment» to the bill that funds the Department of Health and Human Services.

The human brain consists of thousands of different types of nerve cells that are all formed out of what in simple terms can be described as immature stem cells.

These stem cells — known as induced pluripotent stem cells or iPS cells — can be turned into almost any specialised cell type of the human body, including the cells we need to see.

• News of Embryonic Stem Cells • A University of Wisconsin team used human embryonic cells to form cells that manufacture platelets as well as red and white blood cCells • A University of Wisconsin team used human embryonic cells to form cells that manufacture platelets as well as red and white blood ccells to form cells that manufacture platelets as well as red and white blood ccells that manufacture platelets as well as red and white blood cellscells.

The reprogrammed skin cells that have led to this enthusiasm seem to have the same properties as the embryonic stem cells (ESCs) found in human embryos just a few days old.

One possibility is that it's just random events during development, that as a few neural stem cells in a fetus give rise to a hundred billion nerve cells in an adult human brain, a lot of stuff happens.

Mindful of public sensitivities, Daley opted to pursue experiments using what he considers the least controversial human materials to create new nonpresidential stem cell lines — poor quality embryos and oocytes that, in his words, «otherwise would have been disposed of as medical waste.»