Sentences with phrase «human stem cells derived»

While the human stem cells derived through conventional methods failed to integrate into the modified embryos, the human rsPSCs began to develop into early stage tissues.

Scientists at the University of Luxembourg have succeeded in turning human stem cells derived from skin samples into tiny, 3 - D, brain - like cultures that behave very similarly to cells in the human midbrain.

They then used human stem cells derived from bone marrow that would normally become bone cells to test the effects of the nanoparticles on stem cell proliferation and differentiation.

«Investigators create complex kidney structures from human stem cells derived from adults: New technique offers model for studying disease, progress toward cell therapy.»

Endocytosis in a human stem cell derived organoid.

Not exact matches

The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in human embryonic kidney cells, brain cell samples and neurons derived from the stem cells of healthy people and those with spinal muscular atrophy type I and II.

Researchers at Geron, meanwhile, had successfully derived neurons from human embryonic stem cells and were pursuing research that would eventually look to repair the damage caused by spinal - cord injuries, a possible use for embryonic stem cells that was much touted at the time.

But the factor that may make the discovery very significant is that umbilical cord blood can be saved, stored and multiplied without any of the ethical dilemmas facing embryonic stem cell use, which are derived from human fetuses.

For example, animal studies have shown that neurons derived in the lab from human embryonic stem cells improve Parkinson's symptoms; however, any residual stem cells associated with those neurons could form masses of unwanted cells.

Two weeks after the experimental myocardial infarctions, the Seattle researchers injected 1 billion heart muscle cells derived from human embryonic stem cells, called human embryonic stem cell - derived cardiomyocytes, into the infarcted muscle.

The results of the experiment appear in the April 30 advanced online edition of the journal Nature in a paper titled, «Human embryonic - stem cell derived cardiomyocytes regenerate non-human primate hearts.»

Another problem is that in its July 2009 Guidelines on Human Stem Cell Research, NIH spelled out specific requirements about embryo donation for newly derived lines, says Pilar Ossorio, a legal scholar who studies research ethics at the University of Wisconsin Law School.

This image shows an implanted graft of cardiac cells derived from human stem cells (green) meshed and beat with primates» heart cells (red).

The newly discovered human cells, named «cord - blood - derived embryonic - like stem cells» or CBEs, are not quite as primitive as embryonic stem cells, which can give rise to any tissue type of the body.

Currently, Deng's laboratory is conducting additional preclinical studies using the human - derived stem cells from Down syndrome patients and mouse models to determine whether cellular and behavioral abnormalities can be improved with minocycline therapy and other candidate drugs.

Human hematopoietic stem and progenitor cells (HSPCs), derived from bone marrow, have become a primary vehicle for efforts to replace or regenerate cells destroyed by a variety of diseases.

The stem cells, derived from human umbilical cord - blood and coaxed into an embryonic - like state, were grown without the conventional use of viruses, which can mutate genes and initiate cancers, according to the scientists.

Human parthenogenetic embryos are not viable — they run into developmental snags and can not give rise to a person — but the stem cells derived from these embryos could still have research or therapeutic value.

A person with spinal injuries today went down in history as the first to receive a treatment derived from human embryonic stem cells (hESCs).

Tufts University biomedical engineers recently published the first report of a promising new way to induce human mesenchymal stem cells (or hMSCs, which are derived from bone marrow) to differentiate into neuron - like cells: treating them with exosomes.

A company called Hematech is already breeding genetically engineered cattle (derived from cloned stem cells) that produce human antibodies to fight bacterial infections, and the animals» welfare is not compromised in any way.

In an advance touted as a way around current political logjams, scientists have said they can derive human embryonic stem (ES) cell lines without destroying an embryo.

In 1998, scientists figured out how to derive human embryonic stem cells (ESCs) for medical research, and the method kicked off an intense debate.

Researchers working to understand how to manipulate this powerful tool get their supply from stem cell lines, groups of stem cells derived from animal or human tissue that can reproduce themselves indefinitely.

So far only two Japanese groups have been authorized to derive human embryonic stem cells; one group has actually done so.

Attrition of novel drug candidates due to cardiovascular liabilities (including proarrhythmic risk due to delayed ventricular repolarization and Torsades - de-Pointes arrhythmia) remains a hurdle for drug discovery efforts, a hurdle which may be mitigated by the use of human induced pluripotent stem - cell derived (hiPSC)- cardiomyocytes.

The only field that is controversial is research using stem cells that are derived from human embryos.

The use of bone marrow - derived stem cells is well established in the treatment of human cancer patients, and veterinary applications for bone marrow - and adipose - derived stem cells are being evaluated.

To perform this lifesaving work, scien - tists use adult stem cells derived from the cells of mature or recently born humans or animals.

George Daley, speaking of potential therapeutic testing of parthenote - derived stem cells (the sort that his lab reported isolating last December), said it was «reasonable» to assume that the technology wouldn't be ready for human testing for another seven years.

This is an image of human stem cell - derived beta cells that have formed islet like clusters in a mouse.

In June Italian scientists announced the first human embryonic stem cells derived from parthenotes — embryo - like structures formed when an egg starts to divide on its own, with no sperm involved.

Human neural stem cells are derived via fluorescence - activated cell sorting (FACS) from donated fetal brain tissue.

But if homologous recombination could be worked out in human (embryonic) stem cells, then cardiomyocytes with mutations in ion channels could be derived, as well as a large number of other very useful disease models of other tissues.

Twelve months after being injected with brain - derived stem cells near the injury site, one of the three human participants has regained some feeling in the lowest portions of his spine.

«This work provides a proof of principle for using stem cell - derived human intestinal organoids in a therapeutic setting.»

One uses primary hepatocytes obtained from livers donated for transplant; the second uses stem cells derived from human skin samples and guided into hepatocyte - like cells, Bhatia says.

(Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts Nature Biotechnology)

Future research Because there are few salivary gland stem cells in the human mouth, the scientists plan to continue using rat salivary glands to refine the process, but eventually hope to use stem cells derived from human bone marrow or umbilical cord blood to regenerate salivary glands for humans.

In March, President Barack Obama lifted Bush's ban on using federal funds for research on human embryonic stem cells derived after August 2001.

In February 2004 Hwang and his research group reported the first embryonic stem cell line derived from a cloned human embryo.

One is using cells derived from human embryonic stem cells to treat spinal cord injury (although funding problems have stopped the trial enrolling new patients) and another is testing a treatment for age - related macular degeneration.

To address these limitations, investigators from Japan developed a strategy to derive functional platelets from human induced pluripotent stem cells.

He reported in May 2013 using the Dolly technique, known more formally as somatic cell nuclear transfer, to derive stem cells from cloned human embryos, including from a baby with an inherited disorder.

Months to years after transplantation, retinal cells derived from human embryonic stem cells appear healthy — and may have unexpectedly helped vision in some recipients

When a team of South Korean scientists announced in February that they had successfully derived stem cells from a cloned human embryo, they trumpeted the potential someday to treat disorders from diabetes to spinal cord injuries.

So - called induced pluripotent stem (iPS) cells, which are derived from adult human tissue, have the added advantage of producing tissues and organs genetically matched to a recipient, avoiding the problem of immune system rejection.

Rather than clone humans, researchers take the early stage embryos that result from SCNT and then derive stem cells (pictured above, fluorescently tagged red).

Still, many medical researchers insist that the cloning of human embryos continue because the tissue derived from stem cells might treat diseases ranging from diabetes to Parkinson's.

Previous research in rodent disease models has shown that transplanted oligodendrocyte precursor cells derived from embryonic stem cells and from human fetal brain tissue can successfully create myelin sheaths around nerve cells, sometimes leading to dramatic improvements in symptoms.