«Scientists tissue - engineer functional part
of human stomach in laboratory: Researchers can grow functional stomach and intestinal tissues to study diseases, new drugs.»
«We couldn't engineer
human stomach tissue in a petri dish until we first identified how the stomach normally forms in the embryo,» explains Wells.
This confocal microscopic image shows tissue -
engineered human stomach tissues from the corpus / fundus region, which produce acid and digestive enzymes.
This is the first preclinical model of stomach cancer that repeats the pattern of
human stomach cancer development, that involves progression from chronic stomach inflammation through to fully invasive cancer,» Dr Putoczki said.
A research group at Cincinnati Children's Hospital Medical Center used human pluripotent stem cells (hPSCs) to
grow human stomach tissue (paywall)-- and, notably, the part of the organ that produces digestive enzymes.
Immunohistochemical staining of paraffin embedded
human stomach with purified ab32518 at a working dilution of 1 in 100.
Human stomachs make hydrochloric acid instead, and that's designed to break down protein, not starch.
The findings, in mice and in
human stomach cells, also raise questions about how cancer cells may evade treatment.
Researchers now plan to study the ability of tissue - engineered
human stomach organoids to model human gastric diseases by transplanting them into mouse models.
Researchers have managed to get stem cells in the lab to grow
into human stomachs smaller than a single pea.
Scientists report in Nature using pluripotent stem cells to
generate human stomach tissues in a petri dish that produce acid and digestive enzymes.
A
typical human stomach can actually hold all those eggs, as demonstrated in an episode of the Food Network's «Food Detectives.»
I disagree with Dr. Greger and the conventional wisdom (the majority of probiotic supplement makers) that it's better to make an effort to increase the survival of lactobacilli and bifidobacteria through the highly
acidic human stomach.
Scientists soon were concocting tiny facsimiles
of human stomachs, livers, kidneys, lungs and more (SN: 12/28/13, p. 20).
Aug. 8, 2017 — Using bioinformatics approaches, Vanderbilt investigators have identified gene expression networks that are deregulated in mouse and
human stomach cancers.
Just this past summer, Starbucks unveiled the 31 - ounce Trenta, which the National Post noted was larger than
the human stomach.
Thirty to fifty percent of all food produced never reaches
a human stomach.
With millions of pounds of 1080 - treated baits on Western lands, one ponders the issue of how much of this poison is absorbed by grazing livestock from contaminated grasses, and subsequently transferred to
human stomachs in a leg of lamb or roast of beef.»
The lumps of living tissue, which are no bigger than a sesame seed, have a gland structure that is similar to
human stomachs and can even harbour gut bacteria.
Helicobacter pylori sets up shop in
the human stomach and can reside there for years or decades.
Among the 1.6 million base pairs in H. pylori's circular chromosome are some 1590 genes, many of which code for molecules that help the bacterium colonize
the human stomach, reports TIGR molecular biologist Jean - François Tomb.
The abomasum is the actual stomach and is similar in anatomy and function to
the human stomach.
Helicobacter pylori is a spiral bacterium that can colonize
the human stomach — sometimes with fatal consequences.
In order to ensure permanent survival in
the human stomach, Helicobacter pylori must attach to the epithelial cells in the gastric mucosa.
His version of the cry of a tyrannosaurus resembles the noise made by
a human stomach after a bad night in a cheap restaurant — not the fierce sound of the creature in Jurassic Park.
Most bacteria can not survive in the acidic environment of
the human stomach, but Helicobacter pylori, a major cause of ulcers, thrives under such circumstances.
The discovery means investigators now can grow both parts of
the human stomach to study disease, model new treatments and understand human development and health in ways never before possible.
The current study caps a series of discoveries since 2010 in which research teams led or co-led by Wells used human pluripotent stem cells (hPSC)-- which can become any cell type in the body — to engineer regions of
the human stomach and intestines.
Since the mouse stomach has a slightly higher pH than
the human stomach, the researchers believe it will be even more effective in the greater acidity of the human stomach, Chen said.
In a series of studies published since 2009, researchers in Wells» laboratory used human pluripotent stem cells (hPSCs) to grow embryonic - stage small intestines with a functioning nervous system, and the antrum and fundus regions of
the human stomach.
This was no parasite but a rare view of the inside of
a human stomach as it performed rhythmic peristalsis, crushing and churning solid foods into particles one tenth of an inch (2.5 millimeters) in diameter.
The effect of colonization of cdrA (cell division - related gene)- disrupted Helicobacter pylori to host response in
human stomach.
Gastric adenocarcinoma is the second leading cause of cancer - related death in the world, and Helicobacter pylori, a bacterial species that persistently colonizes
the human stomach and induces chronic gastritis, is the strongest known risk factor for this malignancy.
That view began to change in 1982, when two Australian scientists, Robin Warren and Barry Marshall, found spiral - shaped bacteria called Helicobacter pylori in
human stomachs.
The human stomach is a pear - shaped chamber filled with a highly noxious cocktail of hydrochloric acid and protein - cleaving digestive enzymes called peptidases.
However, the researchers say they've identified an enzyme called EP - B2 that successfully digested gluten in an acidic environment similar to that of
a human stomach.
Grains contain phytases (enzymes that break down phytate) and if these have not been inactivated by extrusion (breakfast cereals) or heat treatment there is appreciable degradation of phytates in
the human stomach and intestines.
The research team took various proteins (WPC, micellar casein and the new micellar whey) and incubated them while they were digesting via protease activity at a pH of 2 (which matches the pH of
the human stomach).
Parietal cells are mainly present in the gastric corpus and fundus, although complete mapping in
the human stomach is not fully known.
The thiosulphanate compound allicin digests into sulfenic acid upon reaching
the human stomach, and according to this study, sulfenic acid deactivates free radicals faster than any other antioxidant known to science.
The human stomach has a limited capacity for digestion.
Cancer Flavonoids — a phytonutrient with anti-cancer properties abundant in spinach — have been shown to slow down cell division in
human stomach and skin cancer cells.
A year and a half ago, I read, «Wheat Belly» by cardiologist Dr. William Davis, who gives scientific evidence that
human stomachs were NOT made to digest grains like ruminant animals.