Sentences with phrase «human telomerase»
Human telomerase refers to an enzyme found in our cells called telomerase. It plays a crucial role in protecting and maintaining the ends of our chromosomes, known as telomeres. Telomeres act like protective caps to prevent damage to our DNA during cell division. Without telomerase, telomeres would shorten each time cells divide, leading to aging and deterioration. Human telomerase helps extend the length of our telomeres, ensuring the stability and health of our DNA, which is vital for our overall well-being. Full definition
Dendritic cells reconstituted with human telomerase gene induce potent cytotoxic T - cell response against different types of tumors.
asteriasbiotherapeutics.com
Tocotrienols also inhibited protein kinase C activity, which caused down - regulation of human telomerase reverse transcriptase (hTERT) expression, thereby reducing telomerase activity.
A single nucleotide incorporation step limits human telomerase repeat addition activity.
Greider and Ariel Avilion, a grad student working in her lab toward a Ph.D. from the State University of New York, Stony Brook, were attempting to find and isolate the gene for the RNA portion — dubbed hTR — of human telomerase.
The mouse telomerase RNA component was cloned and contained only 65 percent sequence identity with the human telomerase RNA.
The shorter template regions of the mouse and other rodent telomerase RNAs could account for the shorter distribution of products (processivity) generated by the mouse enzyme relative to the human telomerase.
This catalytic cycle determines the ability of the human telomerase enzyme to synthesize DNA «repeats» (specific DNA segments of six nucleotides) onto chromosome ends, and so afford immortality in cells.
Rs 2736089 is located in the gene encoding the human telomerase reverse transcriptase (TERT), which directs the addition of repeat DNA sequences to the ends of chromosomes.