Not exact matches
The biopharma world went into a bit of a frenzy on Tuesday
as Nature reported that a team of Chinese scientists had become the first in the world to launch
human trials of the groundbreaking CRISPR gene - editing technology.
«That Sudan continues to prosecute these men, and without even allowing them free access to their legal team, makes a mockery of the judicial process and is a clear violation of fair
trial principles,
as articulated in Article 7 of the African Charter on
Human and Peoples Rights (ACHPR) and Article 14 of the International Covenant on Civil and Political Rights (ICCPR), to which Sudan is a party.
The
trial set modernists, who said evolution was consistent with religion, against fundamentalists who said the word of God
as revealed in the Bible took priority over all
human knowledge.»
In 1841, defending African men on
trial for rebelling against slavetraders who had abducted them, John Quincy Adams said: «In the Declaration of Independence, the Laws of Nature are announced and appealed to
as identical with the laws of Nature's God» and
as the foundation of all obligatory
human laws.»
The incongruities themselves illustrate the manner in which through
trial and error men came to apprehend the truth; and the defects and limitations of which we are aware serve
as background to the growing light which,
as if evoked by them, shone upon the
human scene.
Jane, Buddhism is one of the great religions of the world, in panthrotheism it is one of all religions that God had willed to serve
humans who believes on its doctrine.But since we are all
humans, we have to experience all the
trials of life so that in the future when His Will shall be implemented by us, the wisdom of experience of all religions will be the basis of our decisions.Thats why genocides, wars,, pestilence, natural calamities, and all what we percieve
as injustices, such
as tyranny, persecutions and all the negative events in history is part of His will, because in panthrotheism, there is no devil or satan.everything has a reason.and we have to accept it, Remember that He is not faith selective but performance appreciative, it is the good things you do that He wills.
Professor Metcalf testified at the real
trial, «It is impossible for a normal
human being, cognizant of the facts, to have the slightest doubt about the fact of evolution,» and the fictional Drummond argues, «What Bertram Cates spoke quietly one spring afternoon in the Hillsboro High School is... incontrovertible
as geometry in every enlightened community of minds.»
Nor does it stop them from destroying field
trials designed to address questions around environmental impact, performance, and effectiveness
as a
human food.
«Previous research, including
human clinical
trials, supports that diet beverages are an effective tool
as part of an overall weight management plan.
The
human trials are limited —
as is often the case with food research — but the anecdotal evidence of chia's positive health effects include boosting energy, stabilizing blood sugar, aiding digestion, and lowering cholesterol.
We are
human, and
as humans we learn by doing, by experiencing, by exercising our free will
as we stretch and grow and discover and make mistakes and overcome life and are overcome by life, each
trial and failure and success a learning experience.
Schanler R.J., Lau, C., Hurst, N.M., & Smith, E.O. Randomized
trial of donor
human milk versus preterm formula
as substitutes for mothers» own milk in the feeding of extremely premature infants.
Further well designed
human trials are required before its potential efficacy
as a galactagogue can be established.
The PhD course focuses on various aspects of
human (donor) milk, with
as main study a randomized clinical
trial towards the effects of
human donor milk in very low birth weight infants (the Early Nutrition Study).
«The Chinese authorities» list of
human rights abuses is
as long
as your arm - torture, forced labour, internet repression, unfair
trials, and of course the death penalty.
The Geneva Convention allows them to be «detained or prosecuted under the domestic law of the detaining state for such action; subject of course to international treaties on justice and
human rights such
as everyone's right to a fair
trial.»
Suswam, by his suit filed before the Federal High Court in Abuja, is asking the court to declare his detention in the custody of the DSS since February 25, 2017, without
trial,
as a violation of his fundamental rights, to personal liberty, freedom of movement, and dignity of
human person.
Cameron will have had to be sensitive
as he raised the UK's
human rights concerns - like the
trial of punk protest group Pussy Riot and Russia's rough treatment of foreign businesses, including the branding of non-governmental organisations in Russia
as «foreign agents».
If the qualification were narrowed to comments made by the MP in question, the
trial could be deemed to be unfair under the European Convention on
Human Rights
as the MP could not defend themselves by referring to the comments of other MPs.
While this is the first
trial in the US, there is competition with China
as to who will be able to demonstrate this technology in
humans first.
«If you don't use
as close to the total physiological system that you can, you're likely to run into troubles,» like being surprised by side effects later on in clinical
trials, says William Haseltine, founder and former chairman and CEO of Rockville, Md. — based
Human Genome Sciences.
The results, published online in the journal Brain, Behavior and Immunity, strengthen the case that transgenic Huntington's disease monkeys could be used to evaluate emerging treatments (such
as this) before launching
human clinical
trials.
IHR will test their operation
as hearing aids, including
human trials of the new designs.
The team plans to move the CAR - T treatment into
human clinical
trials, but will build
as many safeguards
as possible into the
trial to minimize risks to people who participate, Monje said.
Ishii notes that if the clinical
trial begins
as planned, it would be the latest in a series of firsts for China in the field of CRISPR gene editing, including the first CRISPR - edited
human embryos, and the first CRISPR - edited monkeys.
«Data from this study serves
as rationale to now include dogs with spontaneous cancers in the advancement and optimization of PMed for
human patients,» according to the study, Prospective molecular profiling of canine cancers provides a clinically relevant comparative model for evaluating personalized medicine (PMed)
trials.
«Computational models like this one might one day be able to predict the clinical course of a disease or injury,
as well
as make it possible to do less expensive testing of experimental drugs and interventions to see whether they are worth pursuing with
human trials,» he said.
It typically takes many years to initiate such
trials because of the stringent safety testing that must be done before testing in
humans begins, but Reynolds said it may be possible to move faster
as the therapy only involves modifying a patient's dietary intake and supplementing with a medium - chain triglyceride oil, both of which have no known side effects.
«We know that urate has neuroprotective properties in animal models, and an unusual convergence of
human studies suggested its possible use
as a disease - modifying strategy in Parkinson's; so the positive results of this
trial are very encouraging.»
These techniques include:
human tissue created by reprogramming cells from people with the relevant disease (dubbed «patient in a dish»); «body on a chip» devices, where
human tissue samples on a silicon chip are linked by a circulating blood substitute; many computer modelling approaches, such
as virtual organs, virtual patients and virtual clinical
trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in
humans, safely and with unsurpassed accuracy.
In the newly reconstituted Scientific Responsibility,
Human Rights, and Law Program, the missions of the CSFR and NCLS continue to complement one another
as staff pursue projects such
as continuing seminars for judges on neuroscience and the law, personalized medicine, the state and future of clinical
trials, advocacy in science, understanding responsible research practices in changing research environments, and joint AAAS - China Association of Science and Technology workshops on science and ethics.
The researchers reprogrammed the cells to create induced pluripotent stem cells in an FDA - compliant facility at the Broad Stem Cell Research Center; the use of this facility is an important step in the process
as preclinical research moves toward
human clinical
trials.
Sharpe highlights several hurdles on the route to a
human equivalent of the drug, such
as creating an oral version rather than the injectable form used in the rodent
trials.
In the
human trial saturated fat was replaced by polyunsaturated fat in key food items such
as spread on bread, fat for cooking, cheese, bread and cereals.
Science Immunology publishes original research in all areas of immunology, including new tools and techniques
as well
as human trials.
Niklason hopes that other simple engineered tissues, such
as the blood vessels she has been working on, will be ready for
human trials within a year.
Samuel Weiss, PhD, Professor and Director of the HBI, and Research Assistant Professor Artee Luchman, PhD, and colleagues, published their work today in Clinical Cancer Research, which is leading researchers to start a
human phase I / II clinical
trial as early
as Spring 2015.
In February, Todd Kuiken and colleagues at the Rehabilitation Institute of Chicago announced promising results from the first
human trials of prosthetic limbs based on an approach known
as targeted muscle re-innervation.
AAV1 is considered safe
as a viral vector and is already in use in
human gene therapy
trials for blindness, heart disease, muscular dystrophy and other conditions.
But cognitive studies suggest primates use tools mainly by
trial and error, whereas
humans understand the principles at work — such
as gravity and force — and exploit them to make novel tools.
They are also reaching out to drug industry partners to investigate the potential of initiating
human trials to test glutamate blockers
as PTSD therapeutics, which may take several years to assemble.
Today, preparations are being made to begin phase IIa
human trials on this promising compound
as a single - dose cure.
Since L - arginine can be given to women
as a simple, safe, and inexpensive food supplement, (in peanuts, for example) in pregnancy, Dr. Kain and Dr. McDonald are now planning
human clinical
trials to assess its impact on
human birth outcomes.
But sometime within the next few years, Min and Rhee plan to run clinical
trials in
humans to see whether FlaB - enhanced bacteria could work
as a safe, effective anticancer therapy.
If THI continues to show promise
as a nutraceutical or food - based drug, medical scientists will head into pre-clinical studies of effectiveness and safety before advancing to
human trials.
As she and her colleague wrote in their 2016 paper, they consider nonpublication a «violation of the ethical imperative to share results of
trials that involve
human subjects.»
Bristol - Myers Squibb won its citation «for extending and enhancing
human life through innovative pharmaceutical research and development, and for redefining the science of clinical study through groundbreaking and extremely complex clinical
trials that are now recognized
as industry models.»
Flake's team has patented the device and is in consultation with the Food and Drug Administration to plan a preclinical
trial in animals
as a prelude to doing a
trial in
humans.
As they develop
human clinical
trials, Wargo and colleagues also are conducting lab and mouse model research to better understand the mechanisms that connect bacteria and the immune system.
Further testing and
human clinical
trials are needed to determine if favipiravir, also known
as T - 705 and Avigan, could effectively treat Lassa virus infection in people.