On the logistics end, it is easier to manufacture certain stem - cell therapies, which will be key for
human trials like the heart - muscle - regeneration program.
Not exact matches
Shorn of
human weaknesses
like the need to eat or sleep, computers are now speed - reading through not only the vast academic literature but also CT scans, electronic medical records, and mountains of data from clinical
trials and genomic studies.
By
human courts,
like the OJ or Judy Arias
trials where they were proven not guilty because of the reasonable doubt that they are innocent.
This summer when a Lake Katrine man was on
trial for using a civilian drone outside a Town of Ulster medical building, Ulster County Assistant District Attorney Tom Colonna summed up «drone anxiety» by telling the jury that the machines «put
human eyes in a place,
like 30 feet in the air outside an exam room window, where
human eyes normally wouldn't be.»
Cameron will have had to be sensitive as he raised the UK's
human rights concerns -
like the
trial of punk protest group Pussy Riot and Russia's rough treatment of foreign businesses, including the branding of non-governmental organisations in Russia as «foreign agents».
«If you don't use as close to the total physiological system that you can, you're likely to run into troubles,»
like being surprised by side effects later on in clinical
trials, says William Haseltine, founder and former chairman and CEO of Rockville, Md. — based
Human Genome Sciences.
«Computational models
like this one might one day be able to predict the clinical course of a disease or injury, as well as make it possible to do less expensive testing of experimental drugs and interventions to see whether they are worth pursuing with
human trials,» he said.
Next, researchers would
like to study how the two - drug approach works in
humans, although no clinical
trials have yet been designed or scheduled.
«At the same time, small - scale
trials have shown that consuming antioxidant - rich foods
like virgin olive oil, tomatoes and berries improved HDL function in
humans.
Through the multiple
trials, they confirmed that the spintronic devices have a learning ability with which the developed artificial neural network can successfully associate memorized patterns from their input noisy versions just
like the
human brain can.
«However, while these encouraging results in mice mean that the zinc finger looks
like a good candidate to take forward to
human trials, we still need to do a lot of work first to answer important questions around the safety of the intervention, whether repeat treatments are effective, whether there might be longer - term side effects, and whether we can extend and increase the benefits beyond six months.
Jiang estimates that
human clinical
trials could begin within a decade: «At first, the cells could be used to treat diseases with single missing or malfunctioning cell types,
like hemophilia, diabetes, Parkinson's disease, and muscular dystrophy.
Advisory committee members say they'd
like more animal data on mitochondrial replacement techniques, but don't rule out allowing
human trials
Ross says that because the hyperactivity and decreased anxiety might be interpreted as «mania -
like» symptoms, the researchers fed the mice either lithium or valproic acid (an anti-seizure drug, also used to treat mania) over a two week period, as is often done in
human therapeutic
trials.
«I
like the idea, but I wouldn't want to rush into
human trials yet,» he says.
Like other parts of the GI tract grown by the researchers, the
human colon organoids also create a potential new platform for testing new drugs before the start of clinical
trials.
In response to similar concerns about
human studies, the U.S Food and Drug Administration (FDA) in 2007 mandated that researchers conducting
human clinical
trials preregister the details in an online database
like ClinicalTrials.gov.
«But
human trials of sitagliptin have been limited to date because they have lacked important tools
like a placebo arm and allocation concealment (in which researchers do not know what the next treatment allocation will be, further preventing selection bias in testing),» said Loomba.
Promote
human clinical
trials of repurposed drugs, in collaboration with medical centers (
like UC San Francisco) and pharmaceutical companies in the US and abroad.
How would this development (and whatever drug or therapy they devise for
humans) move from the lab and into
trials, without it taking decades,
like the author here proposes?
Human challenge
trials like this one are an extremely efficient way for scientists to tell whether a particular vaccine is effective, but they are rarely conducted because of the ethical dilemma of the risk it places on volunteers who are purposely exposed to a virus.
The
human like T cell epitopes may contribute to the delayed, low titer of H7N9 hemagglutination inhibiting antibody responses and diminished seroconversion rates that have been observed in
human infections and unadjuvanted H7 HA vaccination clinical
trials.
In recent years, researchers have developed so - called «senolytic» drugs that wipe out senescent cells in aging mice and mouse models of age - related disease, exploiting the high dependence of these cells on specific biochemical survival pathways.9, 10 In these studies, senolytic drugs have restored exercise capacity9 and formation of new blood and immune precursor cells11 in aging mice to near youthful norms, and prevented or treated mouse models of diseases of aging
like osteoarthritis, 12 fibrotic lung disease, 13 hair loss, 14 atherosclerosis, 15,16 and age - related diseases of the heart itself.9 UNITY Biotechnology is leading a growing charge toward the clinic, with
human clinical
trials expected to begin in 2019.
Extensive
human clinical
trials have shown medicinal mushrooms
like shiitake, maitake and coriolus to have potent and powerful immune stimulating properties and many people report much lower rates of illness when they are used regularly.
Playing up a younger Lara's doubts and fears makes her feel more
human, but her physical
trials - impalement and bone - crunching drops, swimming through a literal river of blood - feel uncomfortably
like torture porn.
His life caromed
like few others: from the heights of football celebrity and corporate pitchdom to the lows of an infamous highway Bronco chase and a
trial that showed off the worst of
human nature.
To Lewis» knowledge, no other companies have created a network
like One Health's, nor have an eye to improving
human trials in the way the company does.
Dogs,
like their
human companions, can be susceptible to skin cancer, and the Oncology Service at Auburn University's College of Veterinary Medicine could use the help of man's best friend in launching a clinical
trial to test a new melanoma treatment drug.
If you do decide to treat your dog,
like in
human medicine, there are clinical
trials going on that may help your dog.
The system runs just
like human clinical
trials.
By attempting to give you
human -
like physics based game play fueled by
human -
like trial and error and
human -
like human - likeness.
At the urging of the American Board of
Trial Advocates and the State Bar of California, all incoming attorneys will have to pledge to act
like normal
human beings.
Appreciating just how difficult and challenging it is to work in the
human resource department of an organization, I would
like you to know that I am prepared for any
trials that may come my way.