Researchers are trying to pin down the origins of both HIVs to understand how often new
human viruses emerge.
Not exact matches
An international team of influenza researchers in China, the United Kingdom and the United States has used genetic sequencing to trace the source and evolution of the avian H7N9 influenza
virus that
emerged in
humans in China earlier this year.
Ebola
virus causes severe hemorrhagic fever in
humans and nonhuman primates with high mortality rates and continues to
emerge in new geographic locations, including West Africa, the site of the largest outbreak to date.
The
virus «
emerges» when
human activity, such as habitat destruction, causes host -
human contact.
Haddow, who studies how pathogens survive in the jungle and
emerge when
humans encroach, had a great personal interest in Zika: His grandfather, Alexander Haddow, was one of three scientists who had isolated the
virus from a rhesus monkey in the Zika Forest near Entebbe, Uganda, in 1947 and described it in a paper in 1952.
So H1N1 in itself is a, you know, broad category of
viruses that circulate in
humans, even now; they are not as fearsome as the original strain when it first
emerged.
A new study has found that a novel avian - origin H7N9 influenza A
virus, which has recently
emerged in
humans, attaches moderately or abundantly to the epithelium of both the upper and lower respiratory tracts.
«These characteristics fit with increased virulence of these
emerging avian H7
viruses compared to that of
human influenza
viruses,» says Dr. Kuiken.
Scientists at Dana - Farber Cancer Institute have identified natural
human antibodies against the
virus that causes Middle East Respiratory Syndrome (MERS), a step toward developing treatments for the newly
emerging and often - fatal disease..
Using
virus histochemical analysis, the investigators looked at the pattern of attachment of two genetically engineered
emerging H7
viruses (containing the hemagglutinin (HA) of either influenza
virus A / Shanghai / 1 / 13 or A / Anhui / 1 / 13) to fixed
human respiratory tract tissues and compared the findings to attachment patterns seen with
human influenza
viruses with high transmissibility but low virulence (seasonal H3N2 and pandemic H1N1) and highly pathogenic avian influenza (HPAI)
viruses with low transmissibility and high virulence (H5N1 and H7N7).
«However, the fact that the
emerging H7N9
virus has caused infection mainly in individual
human cases suggests that it has not acquired all the necessary properties for efficient transmission among
humans,» notes Dr. Kuiken.
The report, published in the October issue of The American Journal of Pathology, suggests that the
emerging H7N9
virus has the potential to cause a pandemic, since it may transmit efficiently in
humans and cause severe pneumonia.
«Our results indicate that based just on the pattern of
virus attachment the H7N9 currently
emerging in China has the potential both to cause severe pulmonary disease and to be efficiently transmitted among
humans,» says Dr. Kuiken.
With the emergence of Ebola
virus from bats and hantaviruses from rodents, investigators say identifying the other species infected with HAV provides novel insight into the evolution of HAV and how it spread to
humans, and highlights the utility of analyzing animal reservoirs for risk assessment of
emerging viruses.
Researchers found 53 existing drugs that may keep the Ebola
virus from entering
human cells, a key step in the process of infection, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and the National Institutes of Health (NIH), and published today in the Nature Press journal
Emerging Microbes and Infections.
We will continue to assess the transmissibility of H5N1 influenza
viruses that
emerge in nature and pose a continuing threat to
human health.»
A new study has found that nearly half of camels in parts of Kenya have been infected by the
virus that causes Middle East Respiratory Syndrome (MERS) and calls for further research into the role they might play in the transmission of this
emerging disease to
humans.
Both kill upwards of a third of people infected and, like many
viruses,
emerged from animals — bats and camels in the case of MERS — after mutating into a form capable of infecting
human cells.
HIV, which is thought to have first
emerged in
humans in the 1930s, is another kind of
virus, known as a retrovirus.
More to the point, by genetically stripping dengue
virus of its ability to bind 14 -3-3 epsilon, Gack has generated a crippled
virus that can elicit a strong
human immune response, providing a framework for rational vaccine design against
emerging infectious diseases.
Gack says her goal is to continue to unravel molecular mechanisms that might someday yield antiviral vaccines and drugs not only for
emerging and re-
emerging viruses but also tumor - inducing
viruses, such as certain herpesviruses and
human papillomaviruses.
Further, a newly
emerging African flavivirus, Bagaza
virus [18], both causes
human illness [4], [19] and infects birds in Africa [20], [21].
As recent advances in scientific understanding of Parkinson's disease and cancer immunotherapy have shown, our gut microbiomes — the trillions of bacteria,
viruses and other microbes that live within us — are
emerging as one of the richest untapped sources of insight into
human health.
The long - time focus of the Simmons lab has been on
emerging and reemerging
human viruses, from Ebolavirus and SARS - CoV through to the current Zika
virus epidemic.
«Since Zika
virus has
emerged as a global health emergency, most research has focused on the
virus and its effects on
humans.
A recent estimate suggests over 320,000 mammalian
viruses are still to be discovered but haven't yet
emerged in
humans.
Several interventions have been demonstrated to be effective in reducing the prevalence of behaviors that place adolescents at risk for acquisition of
human immunodeficiency
virus (HIV).1 — 6 These programs have in common a small - group and face - to - face method of delivery, an emphasis on skills development referent to decision making, communication, negotiation and condom use, use of a wide variety of instructional formats and approaches to intervention delivery, and grounding in social learning theory.2 — 6 Despite the encouraging results that accompany these studies with reference to adolescent risk reduction, new challenges have
emerged.
Last century, a
virus called
human immunodeficiency
virus (HIV)
emerged, and it found a weak spot in our immune system's armor.