Sentences with phrase «humans antibodies able»

A malaria vaccine that elicits in humans antibodies able to killPlasmodium falciparum.

Not exact matches

Weiner, Elliott and colleagues studied the DNA sequences for two human monoclonal antibodies — one able to broadly target influenza A viruses and one able to broadly target influenza B viruses — with collaborators at Inovio and MedImmune.

«We have followed a less potent neutralizing lineage in this particular individual before, but now we have found a far more potent antibody and have been able to study its development over six years,» said first author Mattia Bonsignori, M.D., of the Duke Human Vaccine Institute.

Professor Hayday added: «This is very significant because antibodies make up one of the largest sectors of the pharmaceutical market, and one of the great quests in the pharmaceutical industry is to be able to routinely generate antibodies against human proteins implicated in diseases.

To date, no immunization of humans or animals has elicited broadly neutralizing sera able to prevent HIV - 1 transmission; however, elicitation of broad and potent heavy chain only antibodies (HCAb) has previously been reported in llamas.

However, because they don't engage the immune system the way antibodies do, and because of questions of stability and potency, it was not clear whether they would be able to prevent infection in animals, or eventually, in humans.

The mouse TPO receptor is almost identical to human TPO receptor, so Zhang was able to test his antibody agonist in mice.

Using blood collected from elderly persons aged up to one hundred and demonstrating no cognitive impairment, the researchers isolated precisely those immune cells whose antibodies are able to identify toxic beta - amyloid plaques but not the amyloid precursor protein that is present throughout the human body and that presumably plays an important role in the growth of nerve cells.

Researchers have now been able to show that Aducanumab, a human monoclonal antibody, selectively binds brain amyloid plaques, thus enabling microglial cells to remove the plaques.

Human monoclonal antibodies induced during Ebola infection are able to neutralize related viral species, scientists show.