In fact the presence of good
humoral antibody levels blocks the anamnestic response to vaccine boosters just as maternal antibody blocks the response in some young animals.»
The development of CMI is the most crucial factor in determining the ultimate outcome of FIPV infection.4, 5,12 Cats that produce
humoral antibodies but fail to generate an effective CMI response develop effusive FIP.4, 5 Experimental evidence demonstrates that cats with non-effusive FIP often have preceding, transient effusive disease.4 Thus, noneffusive FIP is believed to result from a partially protective CMI response that is unable to wall off and contain the virus.4
Not exact matches
In the so - called
humoral response, B - cells begin to secrete specific
antibody proteins, which latch onto and neutralize pathogens in tissue or blood.
antibody - mediated immunity - protection provided by
antibodies (as opposed to cellular immunity) Also known as «
humoral immunity.»
A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both
humoral and cell - mediated immunity, leukopenia, and low or absent
antibody levels.
Although much is known regarding the specificity and efficacy of
antibody responses, our knowledge of the function, phenotype, and specificity of the antigen - specific B cells that are responsible for
antibody production, as well as for long - term
humoral memory, is inadequate.
SSI offers vaccination studies in mice including 1 - 2 control groups and full immunogenicity analysis including CMI and
humoral immunogenicity using Flow cytometry (B and T cells) and ELISA (cytokines and
antibodies).
For example, previous studies reported that only 23 % of immune sera examined contained specific serum IgG
antibodies against PFA0135w, suggesting that this protein does not normally elicit strong
humoral responses [59].
Th2 cytokines are involved in the
humoral response, leading to the production ofIgE
antibodies.
Production of these
antibodies against the BBB and other neural cell antigens from a cell - mediated and
humoral immune response may indicate a pathological alteration of the protective brain barrier.
In the lymph nodes, «B» type lymphocytes, through their derivative «plasma cells», make
antibodies to the antigens brought by the macrophages (
humoral immunity); and «T» type lymphocytes prepare themselves to attack the foreign antigens (cellular immunity).
It is only in those dogs that have no viral
antibody that the vaccine will booster the immune system, both the cellular and
humoral response to the virus.
It is only in those dogs that have no viral
antibody that the vaccine will boost the immune system, both the cellular and
humoral response to the virus.
Determination of serum
antibody titers is one method commonly used to assess host
humoral immune responses to a number of disease - causing organisms.
By measuring serum
antibody titers annually, one can assess the level of a given dog's
humoral immune response to CPV and CDV.
The rationale for selecting CPV and CDV for serum
antibody testing is based on the clinically important diseases they cause, combined with the usefulness of the host's
humoral immune response to these viruses for determining the need for revaccination.