Deficiency of these compounds impairs both
humoral as well as cell - mediated immunity.
Not exact matches
During his postdoctoral training at the California Institute of Technology, he developed Vectored ImmunoProphylaxis (VIP)
as a means of engineering
humoral immunity, leading to successful demonstration of this approach
as a prophylaxis against HIV
as well
as influenza.
antibody - mediated immunity - protection provided by antibodies (
as opposed to cellular immunity) Also known
as «
humoral immunity.»
cellular immunity - protection provided by the cells of the body's immune system (
as opposed to
humoral immunity).
«In a stressed intestinal environment,» the authors note, «retinoic acid, which was thought to lessen inflammation in the intestine, acted
as an adjuvant that promoted rather than prevented inflammatory cellular and
humoral responses to fed antigen.»
Although much is known regarding the specificity and efficacy of antibody responses, our knowledge of the function, phenotype, and specificity of the antigen - specific B cells that are responsible for antibody production,
as well
as for long - term
humoral memory, is inadequate.
This led to the establishment of international collaborations aimed at preclinical identification, development and selection of HIV vaccine candidates, such
as NeutNet, a worldwide consortium dedicated to the standardisation of HIV neutralisation assays, and the
Humoral Immunity Platform of EUROPRISE.
The SPG cell layer, which is adjacent to the neurons of the brain, forms septate junctions, which function
as a barrier to separate the
humoral space and the brain, analogously to the mammalian tight junctions formed between endothelial cells.
In Stiff Person Syndrome, which is a rare autoimmune disease in the central nervous system with autoantibodies targeting glutamic acid decarboxylase (GAD65), the
humoral autoimmune response was shown to consist of a Rituximab - sensitive part rapidly cleared after treatment, and a Rituximab - resistant part from long - lived and persistent plasma cells acting
as a reservoir for secretion of autoantibodies.
In 2010, we formally demonstrated ADE by developing a mouse mode of ADE - mediated disease, and we began to dissect the contribution of
humoral vs. cellular immune components in dengue vaccine - mediated protection using model vaccine candidates
as tools to probe the mechanisms by which the vaccine - induced immune responses in mice contribute to protection vs. ADE.
Immunization with different Pf AMA1 alleles in sequence induces clonal imprint
humoral responses that are similar to responses induced by the same alleles
as a vaccine cocktail in rabbits.
Nonetheless, the inhibitory substance involved in this
humoral mechanism that may be linked to colonic fermentation is still putative, even though several observations led us to consider a possible involvement of incretins such
as polypeptide YY and glucagon - like peptides (25 — 27).
Recent research has identified that adenosine acts
as a homeostatic regulator of sleep and to be a link between the
humoral and neural mechanisms of sleep - wake regulation.
In fact the presence of good
humoral antibody levels blocks the anamnestic response to vaccine boosters just
as maternal antibody blocks the response in some young animals.»
Vitamin A and E have been shown to enhance immune function in small animals,
as the former can beneficially influence T - helper responses, and the latter is known to improve both cellular and
humoral immunity.
Dr Jean W Dodds, writing in US Dog World, March, 1995, (16) states: «Immune — suppressant viruses of the retrovirus and parvovirus classes have recently been implicated
as causes of bone marrow failure, immune - mediated blood diseases, haematologic malignancies (lymphoma and leukemia), dysregulation of
humoral and cell - mediated immunity, organ failure (liver, kidney) and autoimmune endocrine disorders — especially of the thyroid gland (thyroiditis), adrenal gland (Addison's disease) and pancreas (diabetes).
Nolan's works begin with the close scrutiny of individual literary or artistic works, or evolve out of consciously erratic enquiries into the aesthetics of diverse fields, such
as cosmology,
humoral theory, and illuminated manuscripts.
Nolan's works evolve out of consciously erratic investigations into the aesthetics of diverse fields such
as cosmology,
humoral theory and illuminated manuscripts.