In this instance, researchers added a new analytical «layer» obtained through new spectrometry technology developed at ETH Zürich, making it possible to quantify the presence of
hundreds of proteins from a single sample and establish what experts call each individual's «proteome.»
An amount of
just hundreds of protein molecules will be sufficient to determine a crucial value, called the iso - electric point (pI): this is the pH - value at which the protein has net zero electric charge.
As I had mentioned earlier, it's a very, very complicated process
involving hundreds of proteins, a thousand or so genes, and we really need to delineate exactly all of the changes that are occurring.
Rules - Based Medicine's biomarker testing service provides clinical researchers, physicians and healthcare providers with reproducible, quantitative, multiplexed data
for hundreds of proteins to advance drug development and patient care.
There, he and his team were involved in purifying, characterizing and
crystallizing hundreds of proteins as well as developing novel methods of protein purification and characterization (1999 - 2003).
When a virus invades a cell, one of the body's first signals that it's under attack comes from type I interferon proteins, which then rev up the production
of hundreds of proteins that fight the virus.
Among
the hundreds of proteins modulated by nitrogen starvation, the synthesis ROC40 was the most induced when the cells made the most oil.
Like many viruses, MERS works by hijacking the ubiquitin system in human cells composed of
hundreds of proteins that rely on ubiquitin to keep the cells alive and well.
With those methods, they have successfully revealed the druggability of
hundreds of proteins, many of which had previously been thought un-druggable.