The unique property of
the hydrogel developed by the RIKEN team is that it acts like an artificial muscle, which does not contract equally in all directions.
«Flare - responsive
hydrogel developed to treat arthritis: Researchers develop a better delivery system for anti-inflammatory therapies.»
Tests showed that subcutaneous implants, left, of
a hydrogel developed at Rice University encouraged blood vessel and cell growth as new tissue replaced the degrading gel.
Researchers in the Rice lab of chemist and bioengineer Jeffrey Hartgerink had just such an experience with
the hydrogels they developed as a synthetic scaffold to deliver drugs and encourage the growth of cells and blood vessels for new tissue.
Not exact matches
For example, researchers are
developing «smart» biomaterials such as temperature - sensing
hydrogels that can respond biologically to environmental conditions by changing their biomechanical or drug - releasing properties, says Seeram Ramakrishna, a professor of mechanical engineering and director of the Center for Nanofibers & Nanotechnology at the National University of Singapore.
In related work for drug - release systems built from biocompatible and biodegradable polymers, IMRE has
developed injectable
hydrogels to deliver drugs.
Weaver studied the animal models for as long as 100 days, and found that the islet clusters transplanted with the
hydrogel and VEGF
developed many blood vessels and engrafted into their new locations.
University of Illinois researchers have
developed a new technique to create a cell habitat of squishy fluids, called
hydrogels, which can realistically and quickly recreate microenvironments found across biology.
Her team
developed an earlier bacterial
hydrogel made with the algae - produced polymer alginate, but did not cast it into functional products.
«Electric eel - inspired device reaches 110 volts: Using ion gradients across
hydrogels, researchers
developed a «soft power» source that they hope can one day power implantable devices.»
In an effort to create a power source for future implantable technologies, a team led by Michael Mayer from the University of Fribourg, along with researchers from the University of Michigan and UC San Diego,
developed an electric eel - inspired device that produced 110 volts from gels filled with water, called
hydrogels.
The
hydrogel was created as a spinoff of a separate project — a protein - based glue that can be used in outer space and other extremely dry environments that Sun
developed with Kansas State University's John Tomich, professor of biochemistry.
To create that trigger, the researchers followed a process known as molecular evolution to
develop an antibody that could be attached to the
hydrogel particles to change their form when they encounter thrombin - activated fibrin.
The lab of Matthias Lütolf at EPFL's Institute of Bioengineering has
developed a synthetic «
hydrogel» that eschews the limitations of conventional, naturally derived gels.
In experiments carried out in the lab, BWH bioengineers have
developed a
hydrogel — a soft, flexible material that can be loaded with arthritis drugs and injected locally into an inflamed joint.
Compared to other types of
hydrogels being
developed (left), a new
hydrogel (right) can form crosslinks after injection into the heart, making the material stiffer and longer - lasting.
For instance, his group
developed a
hydrogel that forms additional crosslinks between the polymer chains after injection.
However, chemical engineers at the University of Guadalajara (UdeG), in Mexico,
developed a new technology based on thermosensitive nanoparticles (nano -
hydrogels) to use these materials in the field of biomedicine, as an alternative to achieve controlled release of anticancer drugs.
The research, focused on
developing thermosensitive nano -
hydrogels which, through a polymerization technique, mixes substances with different chemical and physical characteristics, achieving a chemical reaction and forming a set of small spheres called polymers.
The research team also
developed a special syringe for the
hydrogel that would be easy to use on the front lines and capable of quickly cooling the
hydrogel before application.
Mooney and his team decided to mimic the viscoelasticity of living tissue by
developing hydrogels with different stress relaxation responses.
However, the team observed that the microenvironment around bone fractures is very similar to the fastest - relaxing
hydrogel the team
developed in the lab.
Vemula, now affiliated with the Institute for Stem Cell Biology and Regenerative Medicine in Bangalore, India,
developed the
hydrogel with Karp while a postdoc in the Karp laboratory.
Developing a three dimensional in vitro cell culture model for studying breast and prostate cancer using starPEG - heparin
hydrogels.
Now, Mooney and colleagues have
developed new void - forming
hydrogels that help in bone regeneration, or osteogenesis.
We are currently
developing clinical good manufacturing practice (GMP) grade QuickGel
hydrogel.
A few years later, Karl Deisseroth's lab
developed CLARITY, which is a
hydrogel - based method that also allows antibody penetration for immunohistochemical labeling in whole tissue (15).
Specifically, she is examining
hydrogels as a scaffold for tissue engineering and is working to
develop an artificial cornea.
The lab is currently focused on
developing synthetic - biological
hydrogels with highly controlled physical properties and biological function.
REU participants will conduct original research via specially designed student projects within three main foci: 1) Microgel and
Hydrogel Nanoparticles: Designing environmentally sensitive nanoparticles for a variety of applications and fundamental studies of volume phase transitions; 2) Anisotropic Soft Matter Thin Films: Driving self - assembly of soft matter to
develop thin films with unique properties tied to the shape anisotropy of the materials; and 3) Soft Matter Fluid Flow: Striving to better understand and to improve mixing in liquid soft matter systems and use liquid flow to test and understand biological phenomena.
A team of MIT researchers has
developed a new, self - healing
hydrogel that doesn't require surgical implantation, but can be injected using a syringe.
Our Green Tea Water Bomb Mask will deeply replenish while you kick back, infusing your dermis with its carefully
developed «
hydrogel» formula, composed of 95 % organic aloe water and 5 % plant cellulose to intensely hydrate.
Professional Duties & Responsibilities Biomedical and biotechnology engineer with background in design of biomaterials, biosensors, drug delivery devices, microfrabrication, and tissue engineering Working knowledge of direct cell writing and rapid prototyping Experience fabricating nanocomposite
hydrogel scaffolds Proficient in material analysis, mechanical, biochemical, and morphological testing of synthetic and biological materials Extensive experience in bio-imaging processes and procedures Specialized in mammalian, microbial, and viral cell culture Working knowledge of lab techniques and instruments including electrophoresis, chromatography, microscopy, spectroscopy, PCR, Flow cytometery, protein assay, DNA isolation techniques, polymer synthesis and characterization, and synthetic fiber production
Developed strong knowledge of FDA, GLP, GMP, GCP, and GDP regulatory requirements Created biocompatible photocurable
hydrogels for cell immobilization Formulated cell friendly prepolymer formulation Performed surface modification of nano - particle fillers to enhance their biocompatibility Evaluated cell and biomaterial interaction, cell growth, and proliferation Designed bench - top experiments and protocols to simulate in vivo situations Designed
hydrogel based microfluidic prototypes for cell entrapment and cell culture utilizing computer - aided robotic dispenser Determined various mechanical, morphological, and transport properties of photocured
hydrogels using Instron, FTIR, EDX, X-ray diffraction, DSC, TGA, and DMA Assessed biocompatibility of
hydrogels and physiology of entrapped cells Evaluated intracellular and extracellular reactions of entrapped cells on spatial and temporal scales using optical, confocal, fluorescence, atomic force, and scanning electron microscopies Designed various biochemical assays
Developed thermosensitive PET membranes for transdermal drug delivery application using Gamma radiation induced graft co-polymerization of N - isopropyl acylamide and Acrylic acid Characterized grafted co-polymer using various polymer characterization techniques Manipulated lower critical solution temperature of grafted thermosensitive co-polymer Loaded antibiotic on grafted co-polymer and determined drug release profile with temperature Determined biomechanical and biochemical properties of biological gels isolated from marine organisms Analyzed morphological and mechanical properties of metal coated yarns using SEM and Instron Performed analytical work on pharmaceutical formulations using gas and high performance liquid chromatography Performed market research and analysis for medical textile company
Developed and implement comprehensive marketing and sales campaign