Sentences with phrase «hydrogel matrices»

Osteogenic induction of human bone marrow - derived mesenchymal progenitor cells in novel synthetic polymer - hydrogel matrices.

The implant has two main sections: an outer bone - like structure and an inner marrow, both engineered from a hydrogel matrix.

As next steps, the researchers would like to test their hydrogel matrix in animals with normal immune systems and in disease models.

«We have shown that the hydrogel matrix helps the human intestinal organoids (HIOs) engraft into the intestinal tissue, that they differentiate and accelerate the healing of the wound,» said Andrés J. García, Regents» Professor in Georgia Tech's Woodruff School of Mechanical Engineering.

The hydrating mask is made of a hydrogel matrix that releases its ingredients by melting — or «cocooning» — into the skin.

The hydrating mask is made of a hydrogel matrix that releases its ingredients by melting

Not exact matches

The use of hydrogels dressings is a concept stolen from disciplines such as geriatrics, where patients suffer bed wounds and these water - based polymer matrix dressings are applied to maintain moisture, inhibit scab or crust formation, reduce pain, and enhance epithelial migration for wound repair.

Cells grown on hydrogels of the same stiffness all display fat cell markers and deform the underlying matrix material the same way.

By creating fibrous hydrogels with different levels of crosslinks, the team was able to show that cells surrounded by matrices with fewer crosslinks were better able to draw in fibers and increase the number of focal adhesions around them.

Hartgerink is a pioneer in the development of self - assembling multidomain peptide (MDP) hydrogels, which mimic the body's extracellular matrix to encourage the growth of cells and vascular systems for tissue repair.

The nanofiber size and pore size of the hydrogel are in the similar range of a natural extracellular matrix in the biological system.

The authors used the engineered hydrogels to create a 3D growth environment — known as a matrix — which provides optimal physical and biochemical support for organoid growth.

The synthetic hydrogel had disappeared, replaced by natural extracellular matrix produced by the cells themselves.

The team's design for the matrix layer includes calcium ions that are bound to the alginate hydrogel via ionic bonds.

This, says NIST materials scientist Carl Simon, has led to a large and rapidly expanding collection of possible 3D scaffolds, ranging from relatively simple gels made of collagen, the body's natural structural matrix, to structured or unstructured arrangements of polymer fibers, hydrogels and many more.

Matrix engineering: Decellularized or reconstituted biopolymer matrices and modular, biofunctional hydrogels are designed to create cell - instructive microenvironments and morphogenetic matrices for regenerative therapies.

Next - generation «designer matrices» such as hybrid polyethylene glycol hydrogels or microengineered collagen scaffolds, combined with a well - defined set of laminins, may better fulfill the niche requirements of organoids and may be customized for a specific type of tissue / organoid (2,6).

We present here a microfluidic device that generates sub-millimetric hollow hydrogel spheres, encapsulating cells and coated internally with a layer of reconstituted extracellular matrix (ECM) of a few microns thick.