Sentences with phrase «hydrogel scaffolds»

Professional Duties & Responsibilities Biomedical and biotechnology engineer with background in design of biomaterials, biosensors, drug delivery devices, microfrabrication, and tissue engineering Working knowledge of direct cell writing and rapid prototyping Experience fabricating nanocomposite hydrogel scaffolds Proficient in material analysis, mechanical, biochemical, and morphological testing of synthetic and biological materials Extensive experience in bio-imaging processes and procedures Specialized in mammalian, microbial, and viral cell culture Working knowledge of lab techniques and instruments including electrophoresis, chromatography, microscopy, spectroscopy, PCR, Flow cytometery, protein assay, DNA isolation techniques, polymer synthesis and characterization, and synthetic fiber production Developed strong knowledge of FDA, GLP, GMP, GCP, and GDP regulatory requirements Created biocompatible photocurable hydrogels for cell immobilization Formulated cell friendly prepolymer formulation Performed surface modification of nano - particle fillers to enhance their biocompatibility Evaluated cell and biomaterial interaction, cell growth, and proliferation Designed bench - top experiments and protocols to simulate in vivo situations Designed hydrogel based microfluidic prototypes for cell entrapment and cell culture utilizing computer - aided robotic dispenser Determined various mechanical, morphological, and transport properties of photocured hydrogels using Instron, FTIR, EDX, X-ray diffraction, DSC, TGA, and DMA Assessed biocompatibility of hydrogels and physiology of entrapped cells Evaluated intracellular and extracellular reactions of entrapped cells on spatial and temporal scales using optical, confocal, fluorescence, atomic force, and scanning electron microscopies Designed various biochemical assays Developed thermosensitive PET membranes for transdermal drug delivery application using Gamma radiation induced graft co-polymerization of N - isopropyl acylamide and Acrylic acid Characterized grafted co-polymer using various polymer characterization techniques Manipulated lower critical solution temperature of grafted thermosensitive co-polymer Loaded antibiotic on grafted co-polymer and determined drug release profile with temperature Determined biomechanical and biochemical properties of biological gels isolated from marine organisms Analyzed morphological and mechanical properties of metal coated yarns using SEM and Instron Performed analytical work on pharmaceutical formulations using gas and high performance liquid chromatography Performed market research and analysis for medical textile company Developed and implement comprehensive marketing and sales campaign

The cells showed good viability and demonstrated spreading and other phenotypic behavior consistent with cells interacting with collagen hydrogel scaffolds.

The researchers then conducted experiments to have the hydrogel scaffold form at the surgical site after removal of primary tumours.

Not exact matches

Researchers in the Rice lab of chemist and bioengineer Jeffrey Hartgerink had just such an experience with the hydrogels they developed as a synthetic scaffold to deliver drugs and encourage the growth of cells and blood vessels for new tissue.

The researchers reported the natural inflammatory response when a foreign substance like a hydrogel is introduced into a system and draws cells that secrete proteins involved in cellular infiltration, scaffold degradation, vascularization and innervation.

The principle component of the new panel, hydrogel — a polymer network filled with water — is safe to use in and on the human body, having already found use in applications ranging from drug delivery to creating scaffolds for tissue engineering and wound healing.

Engineers at Rutgers - New Brunswick and the New Jersey Institute of Technology worked with a hydrogel that has been used for decades in devices that generate motion and biomedical applications such as scaffolds for cells to grow on.

I found that culturing cardiac valve cells on synthetic hydrogels preserves their normal properties better than the traditional plastic plates do, and I discovered a signaling pathway connecting the stiffness of the supporting scaffold to the cells» cytoskeletal structure.

The injection is made up of a mixture of VentriGelTM, a hydrogel derived from scaffolding protein that is extracted naturally from the heart.

Standard tissue engineering involves seeding types of cells, such as those that form ear cartilage, onto a scaffold of a polymer material called a hydrogel.

Traditional hydrogels made up of either synthetic polymers or natural biomolecules often serve as passive scaffolds for molecular or cellular species, which render these materials unable to fully recapitulate the dynamic signaling involved in biological processes, such as cell / tissue development.

This, says NIST materials scientist Carl Simon, has led to a large and rapidly expanding collection of possible 3D scaffolds, ranging from relatively simple gels made of collagen, the body's natural structural matrix, to structured or unstructured arrangements of polymer fibers, hydrogels and many more.

Next - generation «designer matrices» such as hybrid polyethylene glycol hydrogels or microengineered collagen scaffolds, combined with a well - defined set of laminins, may better fulfill the niche requirements of organoids and may be customized for a specific type of tissue / organoid (2,6).

The three - dimensional vascularization of growth factor - releasing hybrid scaffold of poly (e -LCB- open -RCB-- caprolactone) / collagen fibers and hyaluronic acid hydrogel.

Development of a pre-vascularized 3D scaffold - hydrogel composite graft using an arterio - venous loop for tissue engineering applications.

Hydrogel can be used as a scaffold for engineering artificial brain tissue and promotes the development of neurons...

Specifically, she is examining hydrogels as a scaffold for tissue engineering and is working to develop an artificial cornea.

Landers, R., Hübner, U., Schmelzeisen, R. & Mülhaupt, R. Rapid prototyping of scaffolds derived from thermoreversible hydrogels and tailored for applications in tissue engineering.

Her lab is examining hydrogels as a scaffold for tissue engineering.

In addition, said Zhang, «It is believed that the peptide scaffold hydrogel is generally useful for a wide range of cell / tissue types for regenerative biology and medicine.»