Sentences with phrase «hydrogels as»

Review of «Delivery of Allogeneic Adipose Stem Cells in PEG - Fibrin Hydrogels as an Adjunct to Meshed Autografts After Sharp Debridement of Deep Partial Thickness Burns» from STEM CELLS Translational Medicine by Stuart P. Atkinson

Burmeister DM, Stone R, Wrice N, et al., Delivery of Allogeneic Adipose Stem Cells in Polyethylene Glycol ‐ Fibrin Hydrogels as an Adjunct to Meshed Autografts After Sharp Debridement of Deep Partial Thickness Burns.

Her lab is examining hydrogels as a scaffold for tissue engineering.

Specifically, she is examining hydrogels as a scaffold for tissue engineering and is working to develop an artificial cornea.

Functionalization, preparation and use of cell - laden gelatin methacryloyl - based hydrogels as modular tissue culture platforms.

«Photo - responsive protein hydrogels as agent for controlled stem cell / protein release.»

The therapeutic system will consist of the active agent itself, of a formulation containing the active agent, a hydrogel as carrier material for the formulation, and a suitable applicator for inserting the patch in the nose.

Not exact matches

Based on a 3D image such as an MRI scan, Aspect's machine builds relatively complex organic structures out of a «hydrogel» embedded within cells taken from the body and grown in a cell culture.

The use of hydrogels dressings is a concept stolen from disciplines such as geriatrics, where patients suffer bed wounds and these water - based polymer matrix dressings are applied to maintain moisture, inhibit scab or crust formation, reduce pain, and enhance epithelial migration for wound repair.

Medela Hydrogel Pads provide instant relief from sore nipples by attaching to the skin as a protective, cooling cushion.

In the meantime, USP modified lanolin such as Medela's Tender Care ™ Lanolin and Hydrogel pads are safe and soothing.

You can use warm, wet compresses as a way to soothe the irritated tissue, or use hydrogel to coat your nipples and keep them from scabbing.

«Injectable hydrogels are promising materials for achieving hemostasis in case of internal injuries and bleeding, as these biomaterials can be introduced into a wound site using minimally invasive approaches,» said Gaharwar.

The study uses a commonly used thickening agent known as kappa - carrageenan, obtained from seaweed, to design injectable hydrogels.

Poly - HEMA is a transparent hydrogel that allows the patient to see as drugs from the degrading PLGA layer leak through it onto the eye's surface.

The research team, led by bioengineering professor Adam Engler, also found that a protein binding the stem cell to the hydrogel is not a factor in the differentiation of the stem cell as previously suggested.

For example, researchers are developing «smart» biomaterials such as temperature - sensing hydrogels that can respond biologically to environmental conditions by changing their biomechanical or drug - releasing properties, says Seeram Ramakrishna, a professor of mechanical engineering and director of the Center for Nanofibers & Nanotechnology at the National University of Singapore.

The researchers designed the four hydrogels» chemical makeup so that as soon as all the gels of a single cell touched, their positively charged sodium atoms surged toward one end of the lineup and negative chloride atoms flooded toward the other.

The presented approach uses untethered magnetic micro-robotic coding for precise construction of individual cell - encapsulating hydrogels (such as cell blocks).

Tests showed that subcutaneous implants, left, of a hydrogel developed at Rice University encouraged blood vessel and cell growth as new tissue replaced the degrading gel.

Weaver studied the animal models for as long as 100 days, and found that the islet clusters transplanted with the hydrogel and VEGF developed many blood vessels and engrafted into their new locations.

Mechanical constraints such as soft wire, or glass substrate which chemically binds with the gel, can also be used to manipulate the self - assembly and formation of hydrogels into complex structures.

As expected, the hydrogel material disappeared and was replaced by new tissue which grew around the islets.

The team's findings, published in Proceedings of the National Academy of Sciences today, suggest new applications in areas such as tissue engineering and soft robotics where hydrogel is commonly used.

Researchers in the Rice lab of chemist and bioengineer Jeffrey Hartgerink had just such an experience with the hydrogels they developed as a synthetic scaffold to deliver drugs and encourage the growth of cells and blood vessels for new tissue.

That, Hartgerink said, indicates the hydrogel appears to harness the body's innate capacity to heal as it transitions from a pro-inflammatory to a pro-healing environment.

As more hydrogels were stacked on top of each other, the greater the voltage increase.

The research results are also promising for the potential application of tough hydrogel materials as cartilages.

Engineers at Rutgers - New Brunswick and the New Jersey Institute of Technology worked with a hydrogel that has been used for decades in devices that generate motion and biomedical applications such as scaffolds for cells to grow on.

The resin consists of the hydrogel, a chemical that acts as a binder, another chemical that facilitates bonding when light hits it and a dye that controls light penetration.

These micropatterned elastic hydrogels can one day be used as cardiac patches.

Sun is currently conducting collaborative research with hydrogels for applications and efficiency with anticancer drugs screening and delivery, stem cells and wound healing, as well as being used in vaccines for H1N1 influenza and animal diseases, such as the porcine reproductive and respiratory syndrome virus, or PRRS.

The hydrogel was created as a spinoff of a separate project — a protein - based glue that can be used in outer space and other extremely dry environments that Sun developed with Kansas State University's John Tomich, professor of biochemistry.

Dr Wenxin Wang is trying to uncover therapies for diseases such as diabetic ulcers and Epidermolysis Bullosa, which causes chronic skin conditions: «We are currently investigating the use of these new materials for biomedical applications such as drug / gene delivery, cross linkable hydrogel materials and skin adhesives.

To create that trigger, the researchers followed a process known as molecular evolution to develop an antibody that could be attached to the hydrogel particles to change their form when they encounter thrombin - activated fibrin.

Hartgerink and lead author Vivek Kumar, a postdoctoral researcher at Rice, viewed clotting as a good avenue of investigation for practical application of KOD, a synthetic protein made of 36 amino acids that self - assemble into triple - helix nanofibers and hydrogels.

The team also found that they could control how much the material swelled as well its strength, finding that the ELP hydrogel could withstand more stretching than experienced by arterial tissue in the body.

The new material, known as a photocrosslinkable elastin - like polypeptide - based (ELP) hydrogel, offers several benefits.

The authors used the engineered hydrogels to create a 3D growth environment — known as a matrix — which provides optimal physical and biochemical support for organoid growth.

As next steps, the researchers would like to test their hydrogel matrix in animals with normal immune systems and in disease models.

Hydrogels are materials that are commonly used in everyday objects such as contact lenses or diapers, in order to control humidity.

The idea is that the drug, being within the nano - hydrogels, is transported directly to cancer cells where it can be released without damaging other parts of the body, because hydrogels offer the possibility of dosing a myriad of active substances on the site desired and can be administered as dry or swollen hydrogels by different routes: oral, nasal, buccal, rectal, transdermal, vaginal, ocular and parental.

However, chemical engineers at the University of Guadalajara (UdeG), in Mexico, developed a new technology based on thermosensitive nanoparticles (nano - hydrogels) to use these materials in the field of biomedicine, as an alternative to achieve controlled release of anticancer drugs.

«Since the initial hydrogel's transition temperature was very close to the temperature of the human eye, we had to modify its properties to ensure that it would form a solid seal as soon as the gel was applied to the eye by a soldier or medic,» says lead author Niki Bayat, a doctoral candidate in the Mork Family Department of Chemical Engineering and Materials Science at the USC Viterbi School.

These cells contract and expand — just as they would inside an actual rat heart to make it beat — causing the underlying hydrogel to shrink and stretch too.

To that end, the team made a significant discovery two years ago when it created a revolutionary way to manufacture soft materials using 3D printing and microscopic hydrogel particles as a medium.

Standard tissue engineering involves seeding types of cells, such as those that form ear cartilage, onto a scaffold of a polymer material called a hydrogel.

The hydrogels, which mimic the natural tissues of the body, are specially designed to have an additional feature that's vital to the repair process; they degrade and disappear before the body interprets them as foreign bodies and begins a defense response that could compromise the healing process.

«This makes it problematic for many room temperature biofabrication systems, which are compatible with only a narrow range of hydrogel viscosities and which must generate products that are as uniform as possible if they are to function properly.»

Hydrogels, noted for their biomimetic properties, are the leading materials for biomedical applications, such as drug delivery and stem cell therapy.