Sentences with phrase «hydrogels with»

The lab is currently focused on developing synthetic - biological hydrogels with highly controlled physical properties and biological function.

ANN ARBOR, Mich — By combining engineered polymeric materials known as hydrogels with complex intestinal tissue known as organoids — made from human pluripotent stem cells — researchers have taken an important step toward creating a new technology for controlling the growth of these organoids and using them for treating wounds in the gut that can be caused by disorders such as inflammatory bowel disease (IBD).

The bioactivity of agarose — PEGDA interpenetrating network hydrogels with covalently immobilized RGD peptides and physically entrapped aggrecan.

Mooney and his team decided to mimic the viscoelasticity of living tissue by developing hydrogels with different stress relaxation responses.

The researchers first prepared the anesthetic hydrogels with a polymer to help it stick to the lining of the mouth.

But his team has gone a step further by identifying properties that would be useful in treating heart attack patients and then designing hydrogels with those properties.

So Ke Cheng, Hu Zhang, Jinying Zhang and colleagues wanted to see whether placing stem cells in inexpensive hydrogels with designed tiny pores that are made in the laboratory would work.

By creating fibrous hydrogels with different levels of crosslinks, the team was able to show that cells surrounded by matrices with fewer crosslinks were better able to draw in fibers and increase the number of focal adhesions around them.

To test this idea, the researchers made a hydrogel with A. xylinum.

To demonstrate the technique, the team printed a pattern of hydrogel with cells in the shape of a tree on an elastomer layer.

After an extensive search, a hydrogel with pluronic acid was found to be the most compatible material.

First, it interweaves a gooey, cell - friendly hydrogel with a stiffer substance that offers structural support.

Vemula, now affiliated with the Institute for Stem Cell Biology and Regenerative Medicine in Bangalore, India, developed the hydrogel with Karp while a postdoc in the Karp laboratory.

Not exact matches

There's things you can put into your bra that can reduce the friction of your nipples on your bra: so hydrogel pads, sew dies, these are both really great products that just put a barrier between your nipples and your bra with the pads that you are wearing.

Hydrogel Pads — These gel nipple pads are around the nipple between feeds to provide you with relief for pain between feeds.

The World Health Organization expresses concern with the primary ingredients in hydrogels — the acrylic acid and acrylamide, also called sodium polyacrylate.

Hydrogel Pads: For breastfeeding mothers with nipple discomfort, ComfortGel Extended - Use Hydrogel pads provides relief from soreness by soothing, cooling, and protecting nipples.

Finally, some of the concerns in the media about hydrogels are a case of mistaken identity: Polyacrylate, used in diapers, is sometimes confused with polyacrylamide, a different hydrogel used in horticulture and gardening.

Aqualia Thermal Eyes is a de-puffing, soothing hydrogel that is formulated with a unique combination of carefully selected active ingredients that include beet sugar and horse - chestnut extract.

Hydrogel particles barcoded with unique fluorescent signatures enable detection of multiple biomarkers simultaneously.

In the study, the researchers loaded a hydrogel — a half - inch disc made of a biodegradable sugar naturally found in the human body — with drugs that activate dendritic cells.

To mimic this versatile substance, Joke Bouwstra and Robert Rissman at Leiden University in the Netherlands mixed a range of fatty compounds including lanolin, fatty acids, ceramides and cholesterol with particles made of a water - storing hydrogel (International Journal of Pharmaceutics, DOI: 10.1016 / j.ijpharm.2009.01.013).

Working with Burdick and Chen, who have experience in creating custom three - dimensional hydrogels and fibrous networks with varied crosslinking, the research team ran physical experiments to validate their computer model.

To make a wearable device that can cope with the jostling of everyday life, the team used a water - rich, polyacrylamide hydrogel and added lithium chloride to make it conduct electricity.

The lab reported in the Elsevier journal Biomaterials that a particular hydrogel, a self - assembling multidomain peptide (MDP) with the amino acid sequence K2 (SL) 6K2, is indeed bioactive.

Weaver studied the animal models for as long as 100 days, and found that the islet clusters transplanted with the hydrogel and VEGF developed many blood vessels and engrafted into their new locations.

After that, human clinical trials would be required to show whether the combination of hydrogel material and protein will benefit patients with type 1 diabetes.

Mechanical constraints such as soft wire, or glass substrate which chemically binds with the gel, can also be used to manipulate the self - assembly and formation of hydrogels into complex structures.

Her team developed an earlier bacterial hydrogel made with the algae - produced polymer alginate, but did not cast it into functional products.

Combining a new hydrogel material with a protein that boosts blood vessel growth could improve the success rate for transplanting insulin - producing islet cells into persons with type 1 diabetes.

Researchers in the Rice lab of chemist and bioengineer Jeffrey Hartgerink had just such an experience with the hydrogels they developed as a synthetic scaffold to deliver drugs and encourage the growth of cells and blood vessels for new tissue.

In an effort to create a power source for future implantable technologies, a team led by Michael Mayer from the University of Fribourg, along with researchers from the University of Michigan and UC San Diego, developed an electric eel - inspired device that produced 110 volts from gels filled with water, called hydrogels.

«Modifications of the treatment regimens, additional optimization of the delivery methods via the use of hydrogels, and structural modifications of the compounds via medicinal chemistry could ensure even better results with CDK2 inhibitors in treating hearing loss in humans.»

A tiny chess king, 3D - printed with a temperature - responsive hydrogel, in cold water.

The principle component of the new panel, hydrogel — a polymer network filled with water — is safe to use in and on the human body, having already found use in applications ranging from drug delivery to creating scaffolds for tissue engineering and wound healing.

The 4D printing approach here involves printing a 3D object with a hydrogel (water - containing gel) that changes shape over time when temperatures change, said Howon Lee, senior author of a new study and assistant professor in the Department of Mechanical and Aerospace Engineering at Rutgers University - New Brunswick.

The chitosan and polyvinyl alcohol composite hydrogel containing hTGFβ - 1 gene modified BMSCs was injected into rabbits with defective articular cartilage.

Engineers at Rutgers - New Brunswick and the New Jersey Institute of Technology worked with a hydrogel that has been used for decades in devices that generate motion and biomedical applications such as scaffolds for cells to grow on.

The objects they can create with the hydrogel range from the width of a human hair to several millimeters long.

Sun is currently conducting collaborative research with hydrogels for applications and efficiency with anticancer drugs screening and delivery, stem cells and wound healing, as well as being used in vaccines for H1N1 influenza and animal diseases, such as the porcine reproductive and respiratory syndrome virus, or PRRS.

The hydrogel was created as a spinoff of a separate project — a protein - based glue that can be used in outer space and other extremely dry environments that Sun developed with Kansas State University's John Tomich, professor of biochemistry.

«Hydrogel: Patent issued for substance with medical benefits.»

This hydrogel patent, along with several other patent pending applications, are licensed by the startup company PepGel LLC, which was co-founded by Sun and Huang to make their technology available for research use and medical device applications.

The team reports that ELP hydrogel can be digested overtime by naturally - occurring enzymes and does not appear to have toxic effects when tested with living cells in the lab.

The cells showed good viability and demonstrated spreading and other phenotypic behavior consistent with cells interacting with collagen hydrogel scaffolds.

To test this type of communication in a 3 - D structure, they printed a thin sheet of hydrogel filaments with «input,» or signal - producing bacteria and chemicals, overlaid with another layer of filaments of an «output,» or signal - receiving bacteria.

The researchers then came up with a recipe for their 3 - D ink, using a combination of bacteria, hydrogel, and nutrients to sustain the cells and maintain their functionality.

They choose a model, the K / BxN serum transfer model, in which disease severity can be precisely controlled, which allowed them to test the hydrogel in animals with different degrees of arthritis severity.

When the gel was incubated in synovial fluid from a healthy human joint, drug release was minimal, but when incubated in synovial fluid from a patient with rheumatoid arthritis, the drug was readily released from the hydrogel.

Based on those findings, a handful of labs are now experimenting with hydrogel treatments, including two materials that are in clinical trials.