Not exact matches
Whereas the first is explained by H -
bond with the proteins, the retarded
hydrogen bond dynamics around hydrophobic residues is at first glance surprising and can be explained by the additional imposed steric constraints on the water molecules at hydrophobic
sites.
Integral to the polymer's design are electron - withdrawing fluorine atoms that create
sites on the polymer with more positive
hydrogen atoms leading to stronger
hydrogen -
bonding interactions and more sensitive sensors.
The
hydrogen -
bond latch that holds the jaws together protects its active, or catalytic
site.
It has also been suggested for serine proteases and other enzymes that binding interactions away from the
site of chemical transformation position the substrate such that active
site hydrogen bonds are prevented from achieving their optimal length in the ground state.