The specificity for coupling to the stimulatory guanine nucleotide regulatory protein lies within a region extending from the amino terminus of the fifth
hydrophobic domain to the carboxyl terminus of the sixth.
The two receptors are homologous with each other, rhodopsin, and other receptors coupled to guanine nucleotide regulatory proteins and they contain seven
hydrophobic domains, which may represent transmembrane spanning segments.
Not exact matches
One
domain is functionized with hydrophilic organic ligands and the other with
hydrophobic ones.
We are focusing on PDZ
domains, recognizing
hydrophobic C - termini, and WW and SH3
domains, recognizing proline rich motifs.