Sentences with phrase «hydroxychloroquine in»

Combined autophagy and HDAC inhibition: a phase I safety, tolerability, pharmacokinetic, and pharmacodynamic analysis of hydroxychloroquine in combination with the HDAC inhibitor vorinostat in patients with advanced solid tumors.

Whereas, a phase I / II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme led to no significant improvement in overall survival, which could be due to inconsistent autophagy inhibition in patients treated with this regimen [29].

A phase I / II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme.

Not exact matches

The study shows there was no benefit in taking hydroxychloroquine to control debilitating pain when compared to a placebo (dummy substance).

So doctors have used hydroxychloroquine off - label, in a way that it was not licensed for, to try and control symptoms and pain.

The arms hold it in place while hydroxychloroquine, a malaria medication also shown to calm immune activation, is delivered and slowly absorbed by the walls of the vaginal tract.

Warhurst DC, Steele JC, Adagu IS, Craig JC, Cullander C. Hydroxychloroquine is much less active than chloroquine against chloroquine - resistant Plasmodium falciparum, in agreement with its physicochemical properties.

Distinct non-cancer drugs already investigated in clinical cancer trials comprise metformin, aspirin, hydroxychloroquine and thalidomide [3, 4].

It is also given in conjunction with methotrexate and hydroxychloroquine as part of a regimen of «triple therapy» which has been shown to provide benefits to patients who have had inadequate responses to methotrexate alone.

In preclinical trials, the effect of chloroquine and hydroxychloroquine on tumorigenesis has been extensively investigated in mouse cancer models, including genetic and xenograft models (summarized in Table 2In preclinical trials, the effect of chloroquine and hydroxychloroquine on tumorigenesis has been extensively investigated in mouse cancer models, including genetic and xenograft models (summarized in Table 2in mouse cancer models, including genetic and xenograft models (summarized in Table 2in Table 2).

Combined autophagy and proteasome inhibition: a phase 1 trial of hydroxychloroquine and bortezomib in patients with relapsed / refractory myeloma.

For mild cases, ibuprofen and naproxen can reduce pain and swelling in joints and muscles, and antimalarial drugs like Plaquenil (generic: hydroxychloroquine) have proven useful in preventing flares and controlling the diseases progression.