Sentences with phrase «hydroxylase enzymes»

While the metal copper was found to inhibit the hydroxylase enzymes from converting the procollagen, mercury was found to inhibit every step of the process beginning at the assembling of glycine and proline.

Next the procollagen is catalysed with two hydroxylase enzymes which react with proline and also lysine.

This test shows whether or not there is a mutation in the CYP21A2 gene coding for the 21 - Hydroxylase Enzyme.

In the Classical form of CAH, the 21 hydroxylase enzyme (21 - OH) is severely deficient with resulting low cortisol levels.

Not exact matches

The most recent study report described in these same regions decreased tissue levels of 5 - HT and tryptophan hydroxylase, the synthesizing enzyme for serotonin, and no evidence of excessive serotonin degradation as assessed by levels of 5 - hydroxyindoleacetic acid (the main metabolite of serotonin) or ratios of 5 - hydroxyindoleacetic acid to serotonin.30 A recent article described a significant association between a decrease in medullary 5 - HT1A receptor immunoreactivity and specific SIDS risk factors, including tobacco smoking.40 These data confirm results from earlier studies in humans39, 41 and are also consistent with studies in piglets that revealed that postnatal exposure to nicotine decreases medullary 5 - HT1A receptor immunoreactivity.42 Animal studies have revealed that serotonergic neurons located in the medullary raphe and adjacent paragigantocellularis lateralis play important roles in many autonomic functions including the control of respiration, blood pressure, heart rate, thermoregulation, sleep and arousal, and upper airway patency.

Dopamine - β - hydroxylase is an enzyme that is localized to catecholamine - containing vesicles in sympathetic nerves and the adrenal medulla, and is also found in the serum.

In a series of cell - based studies, they showed that it both blocked a family of iron - containing, oxygen - sensing enzymes called hypoxia - inducible factor prolyl - hydroxylases (HIF - PHD) and, critically, protected neurons by activating genes that protect them from oxidative stress.

To shift into red pigment production, the enzyme flavonoid 3», 5» - hydroxylase (F3» 5 «h) is functionally inactivated in the 13 red - flowered species they examined by mutations that abolish enzyme activity.

Woo's technique may one day be used to treat the metabolic disorder phenylketonuria (PKU), in which the gene for the hepatic enzyme known as phenylalanine hydroxylase (PAH) is defective.

TH or tyrosine hydroxylase is an enzyme in the dopamine synthesis.

Phenylketonuria: Phenylketonuria (PKU) is a genetic metabolic disorder in which a baby is born without an important enzyme known as phenylalanine hydroxylase (PAH).

He did a post-doc in the lab of Professor Chris Schofield working on the Hypoxia - inducible - factor hydroxylase Factor - Inhibiting - HIF and enzymes involved in biosynthesis of clavulanic acid.

Drosophila tyrosine hydroxylase (DTH) is the rate limiting enzyme for DA biosynthesis.

He went on to medical, and graduate neuroscience training at Harvard Medical School to write his PhD thesis on the neurochemistry of tyrosine hydroxylase, the enzyme controlling dopamine biosynthesis.

Dop is converted to norepinephrine by the enzyme dopamine - B hydroxylase with vitamin C as the cofactor.

But these Clostridia species, they create an enzyme, and it's called Dopamine beta - hydroxylase that causes the Dopamine not to break down properly.

In the Non-Classical form however, the 21 hydroxylase (21 - OH) enzyme is still working fairy well with only a slight reduction in activity, and cortisol levels are usually normal, while testosterone levels may be elevated to a variable degree.

Koch discusses the enzyme deficiency: «Phenylketonuria (PKU) is caused by an autosomal recessive defect in the enzyme phenylalanine hydroxylase, which is required for converting phenylalanine to tyrosine.

[1] For those with phenylketonuria, however, a severe deficiency in the enzyme phenylalanine hydroxylase prevents conversion of phenylalanine to tyrosine, making tyrosine an essential amino acid for this population.

Tryptophan hydroxylase may be the oldest enzyme to attach oxygen to other molecules.

The primary structure of human dopamine - beta - hydroxylase: insights into the relationship between the soluble and the membrane - bound forms of the enzyme