Sentences with phrase «hydroxylase gene»

Further evidence for the association between attention - deficit / hyperactivity disorder and the dopamine - beta - hydroxylase gene

Eat broccoli, for instance, and the vitamin B6 it contains will spur the tryptophan hydroxylase gene to produce L - tryptophan, an amino acid used in the synthesis of serotonin, a neurochemical mood stabilizer.

Not exact matches

In a series of cell - based studies, they showed that it both blocked a family of iron - containing, oxygen - sensing enzymes called hypoxia - inducible factor prolyl - hydroxylases (HIF - PHD) and, critically, protected neurons by activating genes that protect them from oxidative stress.

Woo's technique may one day be used to treat the metabolic disorder phenylketonuria (PKU), in which the gene for the hepatic enzyme known as phenylalanine hydroxylase (PAH) is defective.

Genetic analysis revealed that eight people who got relief from the placebo had a particular version of a gene that regulates serotonin production called the tryptophan hydroxylase - 2 promoter (TPH2), the researchers report tomorrow in the Journal of Neuroscience.

The first genes expressed in monocytes exposed to a Mycobacterium antigen were the genes for the vitamin D receptor and vitamin D 1 - α - hydroxylase.

Abbreviations: ACVR2A, activin A receptor type IIA; BMP, bone morphogenetic protein; BMPR, BMP receptor, type II; CNS, Central nervous system; DA, dopaminergic; DMEM / F12, Dulbecco's modified Eagle's medium nutrient mixture F - 12; E, embryonic day; GDF, growth differentiation factor; GO, gene ontology; KEGG, Kyoto encylopedia of genes and genomes; MAPK, Mitogen - activated protein kinase; mDA, midbrain dopaminergic; PD, Parkinson's disease; RIPA, radioimmunoprecipitation assay; SN, Substantia nigra; TGF - β, transforming growth factor - β; TH, tyrosine hydroxylase; VM, ventral midbrain / mesencephalon; Zeb2, Zinc finger E-box-binding homoeobox 2

To explore the possibility of common genetic pathways within the respective pathophysiologies, nine ADHD candidate single nucleotide polymorphisms (SNPs) in seven genes were tested for association with PD in 5333 cases and 12,019 healthy controls: one variant, respectively, in the genes coding for synaptosomal - associated protein 25 k (SNAP25), the dopamine (DA) transporter (SLC6A3; DAT1), DA receptor D4 (DRD4), serotonin receptor 1B (HTR1B), tryptophan hydroxylase 2 (TPH2), the norepinephrine transporter SLC6A2 and three SNPs in cadherin 13 (CDH13).

He developed a Quebec - wide database tracking the incidence of genes that cause metabolic disorders, and his laboratory hosted the online phenylalanine hydroxylase locus knowledgebase, or PAHdb, a resource for scientists and clinicians.

Calcitriol, the hormonally active form of vitamin D, accumulates in the adrenals, and this stimulates the production of the gene for tyrosine hydroxylase, which is involved in serotonin production.

This test shows whether or not there is a mutation in the CYP21A2 gene coding for the 21 - Hydroxylase Enzyme.

Genes encoding the serotonin 2a receptor (HTR2A) and tryptophan hydroxylase 1 (TPH1) have been associated with antisocial personality disorder (ASPD) in adult males [21].