Sentences with phrase «hydroxylase known»
Lack of oxygen is sensed directly by a prolyl hydroxylase known as EGL - 9 in worms and EGLN2 in mammals.
http://science.sciencemag.org/ Not exact matches
Woo's technique may one day be used to treat the metabolic disorder phenylketonuria (PKU), in which the gene for the hepatic enzyme known as phenylalanine hydroxylase (PAH) is defective.
Phenylketonuria: Phenylketonuria (PKU) is a genetic metabolic disorder in which a baby is born without an important enzyme known as phenylalanine hydroxylase (PAH).
The activity of HIF is therefore strictly regulated by a set of oxygen sensors known as the HIF - prolyl hydroxylases (PHDs).