Sentences with phrase «hydroxyurea in»
Jeremie Estepp, MD, said the papers» findings underscore the need to improve and expand access to hydroxyurea in the U.S. and internationally.
https://www.stjude.org/ Not exact matches
In an accompanying editorial, Debra L. Weiner and Carlo Brugnara of Harvard Medical School call for increased use of hydroxyurea.
«This is because while both cell types show hydroxyurea - induced gene expression, collision with replication occurs differentially because replication forks have progressed to different extent in these cells,» said Feng.
«Using the anti-cancer drug and a replication inhibitor, hydroxyurea, in the model organism Saccharomyces cerevisiae, we observed that double strand breaks preferentially occurred at hydroxyurea - induced genes,» said Feng.
St. Jude pioneered the use of hydroxyurea to treat sickle cells in children.
Rather than calculating a standard dose of hydroxyurea based on patients» weight, researchers used a dose - escalation approach to determine the maximum tolerated dose for each of the 230 St. Jude patients enrolled in the study.
Alpha - synuclein functions in the nucleus to protect against hydroxyurea - induced replication stress in yeast.