Sentences with phrase «hyperactivation in»

In males, corticosterone levels were elevated only in response to the 40 % CR diet, whereas in females corticosterone levels were significantly elevated in response to all three energy - restriction diets, suggesting a relative hyperactivation in females of the adrenal stress response to reduced energy availability.

Pilar received her PhD in 2017 at the Complutense University of Madrid, where she studied immune cell dysfunction and hyperactivation in HIV / HCV coinfected patients, as well as the in vitro and in vivo activity of nanoparticles against HIV - 1 and HSV - 2 infections to prevent their transmission in humans as a topical microbicide.

Not exact matches

By studying human cancer cells and animal models of cancer in the lab, our researchers have shown that loss of PTEN leads to high levels of PI (3,4) P2, which could result in hyperactivation of AKT.

«The human genes and pathways that Tat manipulates correlate well with symptoms observed in these patients, such as immune system hyperactivation, then weakening, and accelerated aging,» Dr. D'Orso said, describing the situation in which HIV infection leads to AIDS.

The analysis revealed that while performing working memory tasks, the young patients with concussion had initial activation that was greater than normal, known as hyperactivation, compared to young controls in the right precuneus and right inferior parietal gyrus of the brain, whereas the older patients had hypoactivation (less than normal) compared to older controls in the right precuneus and right inferior frontal gyrus.

In line with our in vitro data, Pkn1 — / — mice showed AKT hyperactivation, elevated NeuroD2 levels, and reduced expression of PF - PC synaptic markers during stages of PF maturation in vivIn line with our in vitro data, Pkn1 — / — mice showed AKT hyperactivation, elevated NeuroD2 levels, and reduced expression of PF - PC synaptic markers during stages of PF maturation in vivin vitro data, Pkn1 — / — mice showed AKT hyperactivation, elevated NeuroD2 levels, and reduced expression of PF - PC synaptic markers during stages of PF maturation in vivin vivo.

These unexpected findings may be related to the epileptic phenotype of many pedigrees of patients with early - onset familial AD and to the hyperactivation of neuronal networks in patients with sporadic AD and amyloid - positive nondemented subjects.

These findings are probably related to the epileptic phenotype of many pedigrees of patients with early - onset familial AD and to the hyperactivation of neuronal networks in patients with sporadic AD and amyloid - positive nondemented subjects.

Catalase abrogates ß - lapachone - induced PARP1 hyperactivation - directed programmed necrosis in NQO1 - positive breast cancers.

Brain functional correlates of working memory: reduced load - modulated activation and deactivation in aging without hyperactivation or functional reorganization.

ST2 contributes to T - cell hyperactivation and fatal hemophagocytic lymphohistiocytosis in mice.

In addition, many cancer cells express insulin receptors (IRs) and show hyperactivation of the IGF1R - IR pathway.

Often, living in a pernicious environment leads to hyperactivation of our immune gut cells and what would normally not cause an immune response, now does.

This hyperactivation results in threats detected in nearly every interpersonal transaction.

Furthermore, this hyperactivation intensifies negative emotional responses to these threats and results in excessive rumination about threats (Mikulincer et al. 2003).