In addition, chronic oral administration of gabapentin (from day 24 — day 44) also reversed paclitaxel - induced mechanical
hyperalgesia when administered at 100mg / kg but not 50 mg / kg.
Researchers already knew that even without opioids, some people with chronic pain from nerve damage or fibromyalgia, for example, experience
hyperalgesia when normal pain signaling gets reinforced and amplified over time.
Not exact matches
«
When I go to work every day, I don't think about opioid - induced
hyperalgesia,» says Gary Bennett, a pain researcher at the University of California in San Diego.
He believes the risk of
hyperalgesia should motivate doctors to try tapering patients off their opioids
when their pain worsens without an obvious cause.
Neuropathic pain develops
when damaged or dysfunctional nerves send inappropriate signals to the brain.7 Neuropathic pain can result from diabetic neuropathy,
hyperalgesia syndrome, previous trauma, and onychectomy.